对甲苯磺酸五氟苄酯 | 32974-36-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 对甲苯磺酸五氟苄酯
• 中文别名: 对甲苯磺酸五氟苄酯[用于无机阴离子的气相色谱的诱导试剂]
• 英文名称: 2,3,4,5,6-Pentafluorbenzyl-toluol-p-sulfonat
• 英文别名: Pentafluorobenzyl p-Toluenesulfonate；(2,3,4,5,6-pentafluorophenyl)methyl 4-methylbenzenesulfonate
• CAS: 32974-36-0
• 化学式: C₁₄H₉F₅O₃S
• mdl: MFCD06248628
• 分子量: 352.282
• InChiKey: BKNSDBYJUGNUDL-UHFFFAOYSA-N

物化性质

• 熔点：
  78°C
• 溶解度：
  溶于甲醇

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.142
• 拓扑面积：
  51.8
• 氢给体数：
  0
• 氢受体数：
  8

安全信息

• 危险等级：
  IRRITANT
• 危险品标志：
  Xi
• 安全说明：
  S26,S36
• 危险类别码：
  R36/37/38
• 海关编码：
  2906299090
• 储存条件：
  室温

SDS

Pentafluorobenzyl p-Toluenesulfonate [Derivatizing Revision number: 5
Reagent for GC of Inorganic Anions]
SAFETY DATA SHEET

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Section 1. IDENTIFICATION
Product name: Pentafluorobenzyl p-Toluenesulfonate [Derivatizing Reagent for GC of Inorganic
Anions]

Revision number: 5

---

Section 2. HAZARDS IDENTIFICATION
GHS classification
Not classified
PHYSICAL HAZARDS
HEALTH HAZARDS Not classified
Not classified
ENVIRONMENTAL HAZARDS
GHS label elements, including precautionary statements
Pictograms or hazard symbols None
Signal word No signal word
Hazard statements None
Precautionary statements: None

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Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance/mixture: Substance
Pentafluorobenzyl p-Toluenesulfonate [Derivatizing Reagent for GC of Inorganic
Components:
Anions]
>98.0%(T)
Percent:
CAS Number: 32974-36-0
PFB - Tosylate , p-Toluenesulfonic Acid Pentafluorobenzyl Ester
Synonyms:
Chemical Formula: C14H9F5O3S

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Section 4. FIRST AID MEASURES
Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention if you feel unwell.
Skin contact: Remove/Take off immediately all contaminated clothing. Rinse skin with
water/shower. If skin irritation or rash occurs: Get medical advice/attention.
Eye contact: Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Get medical advice/attention if you feel unwell. Rinse mouth.
Ingestion:
Protection of first-aiders: A rescuer should wear personal protective equipment, such as rubber gloves and air-
tight goggles.

---

Section 5. FIRE-FIGHTING MEASURES
Dry chemical, foam, water spray, carbon dioxide.
Suitable extinguishing
media:
Pentafluorobenzyl p-Toluenesulfonate
[Derivatizing Reagent for GC of Inorganic
Anions]

---

Section 5. FIRE-FIGHTING MEASURES
Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to
from the chemical: generate poisonous fume.
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protective When extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

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Section 6. ACCIDENTAL RELEASE MEASURES
Use personal protective equipment. Keep people away from and upwind of spill/leak.
Personal precautions,
protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
emergency procedures: roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

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Section 7. HANDLING AND STORAGE
Precautions for safe handling
Technical measures: Handling is performed in a well ventilated place. Wear suitable protective equipment.
Prevent dispersion of dust. Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Storage conditions: Keep container tightly closed. Store in a cool and dark place.
Store away from incompatible materials such as oxidizing agents.
Packaging material: Comply with laws.

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Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Install a closed system or local exhaust as possible so that workers should not be
Engineering controls:
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator. Follow local and national regulations.
Protective gloves.
Hand protection:
Eye protection: Safety glasses. A face-shield, if the situation requires.
Skin and body protection: Protective clothing. Protective boots, if the situation requires.

---

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C): Solid
Form: Crystal- Powder
White - Almost white
Colour:
Odour: No data available
pH: No data available
Melting point/freezing point:78°C
No data available
Boiling point/range:
Flash point: No data available
Flammability or explosive
limits:
Lower: No data available
Upper: No data available
Relative density: No data available
Solubility(ies):
No data available
[Water]
Pentafluorobenzyl p-Toluenesulfonate
[Derivatizing Reagent for GC of Inorganic
Anions]

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Section 9. PHYSICAL AND CHEMICAL PROPERTIES
[Other solvents]
Soluble: Methanol

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Section 10. STABILITY AND REACTIVITY
Stable under proper conditions.
Chemical stability:
Possibility of hazardous No special reactivity has been reported.
reactions:
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide, Hydrogen fluoride, Sulfur oxides
products:

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Section 11. TOXICOLOGICAL INFORMATION
Acute Toxicity: No data available
Skin corrosion/irritation: No data available
Serious eye No data available
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
IARC = No data available
NTP = No data available
Reproductive toxicity: No data available

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Section 12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: No data available
No data available
Crustacea:
Algae: No data available
Persistence / degradability: No data available
Bioaccumulative No data available
potential(BCF):
Mobility in soil
Log Pow: No data available
Soil adsorption (Koc): No data available
No data available
Henry's Law
constant(PaM3/mol):

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Section 13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.

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Section 14. TRANSPORT INFORMATION
Hazards Class: Does not correspond to the classification standard of the United Nations
UN-No: Not listed

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Section 15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.
Pentafluorobenzyl p-Toluenesulfonate
[Derivatizing Reagent for GC of Inorganic
Anions]

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  对甲苯磺酸五氟苄酯 在 potassium fluoride 、 sodium carbonate 作用下， 以 乙醇 、 N,N-二甲基甲酰胺 为溶剂， 生成 N-Methyl-N-pentafluorbenzyl-prop-2-inylamin
  参考文献：
  名称：

  多氟芳族化合物的新反应。第二部分 多氟芳烷基胺

  摘要：

  （±）-苯异丙胺和N-甲基-N-五氟苄基丙-2-炔胺的五氟-（1a）和4-甲氧基-2,3,5,6-四氟-（1b）类似物的制备（25）概述。描述了1-甲基-2-五氟苯基乙基肼（10）和（12）与2-五氟苯基环丙胺（19）的盐的合成。

  DOI：

  10.1039/j39710002062
• 作为产物：
  描述：

  五氟苯甲醇 、 对甲苯磺酰氯 在 sodium hydroxide 作用下， 生成 对甲苯磺酸五氟苄酯
  参考文献：
  名称：

  多氟芳族化合物的新反应。第二部分 多氟芳烷基胺

  摘要：

  （±）-苯异丙胺和N-甲基-N-五氟苄基丙-2-炔胺的五氟-（1a）和4-甲氧基-2,3,5,6-四氟-（1b）类似物的制备（25）概述。描述了1-甲基-2-五氟苯基乙基肼（10）和（12）与2-五氟苯基环丙胺（19）的盐的合成。

  DOI：

  10.1039/j39710002062

文献信息

• FILMS FOR ASSAYING PROTEASE ACTIVITY
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP1270736A1

  公开（公告）日：2003-01-02

  A thin membrane for measuring protease activity, which is formed on a support and, which comprises one or more kinds of substances selected from the group consisting of a transferrin derivative and an albumin derivative and is crosslinked and/or substantially water-insoluble. The membrane enables selective measurement of protease activity of a particular class of protease such as matrix metalloproteinase 7.

  一种用于测量蛋白酶活性的薄膜，它形成于一种支撑物上，由一种或多种物质组成，这些物质选自由转铁蛋白衍生物和白蛋白衍生物组成的组，并且是交联的和/或基本上不溶于水。该膜可选择性地测量特定类别蛋白酶（如基质金属蛋白酶 7）的蛋白酶活性。
• Thin membrane for measuring protease activity
  申请人：Fuji Photo Film Co. Ltd.

  公开号：EP1686188A1

  公开（公告）日：2006-08-02

  A thin membrane for measuring protease activity, which is formed on a support, which comprises an albumin derivative and is crosslinked and/or substantially water-insoluble. The membrane enables selective measurement of protease activity of a particular class of protease such as matrix metalloproteinase 7.

  一种用于测量蛋白酶活性的薄膜，它形成于一种由白蛋白衍生物组成的、交联的和/或基本上不溶于水的支持物上。该薄膜可选择性地测量特定类别蛋白酶（如基质金属蛋白酶 7）的蛋白酶活性。
• Film for assaying protease activity
  申请人：——

  公开号：US20030148399A1

  公开（公告）日：2003-08-07

  A thin membrane for measuring protease activity, which is formed on a support and, which comprises one or more kinds of substances selected from the group consisting of a transferrin derivative and an albumin derivative and is crosslinked and/or substantially water-insoluble. The membrane enables selective measurement of protease activity of a particular class of protease such as matrix metalloproteinase 7.

  一种用于测量蛋白酶活性的薄膜，它形成于一种支撑物上，由一种或多种物质组成，这些物质选自由转铁蛋白衍生物和白蛋白衍生物组成的组，并且是交联的和/或基本上不溶于水。该膜可选择性地测量特定类别蛋白酶（如基质金属蛋白酶 7）的蛋白酶活性。
• METHODS AND COMPOSITIONS OF PREPARATION FOR PROTEOME ANALYSIS
  申请人：Case Western Reserve University

  公开号：US20130172539A1

  公开（公告）日：2013-07-04

  A method of extracting a polypeptide from a biological sample includes contacting the biological sample with an extraction reagent to form a solution of the biological sample and the extraction reagent. The extraction reagent includes perfluorooctanoic and can be used at a concentration effective to solubilize the polypeptides in the biological sample.
• METHOD FOR DETECTING ORGANIC AND INORGANIC EXPLOSIVES
  申请人：1ST DETECT CORPORATION

  公开号：US20150330961A1

  公开（公告）日：2015-11-19

  Methods, devices, and systems are disclosed for releasing a sample from a carrier medium. A method of releasing a sample from a carrier medium comprises treating a sample on a carrier medium with a first organic reagent, wherein when the sample contains at least one inorganic salt, the first organic reagent binds to a cation of the inorganic salt to produce both a first volatile compound and an isolated anion of the inorganic salt; treating the sample on the carrier medium with a second organic reagent, wherein the second organic reagent reacts with the isolated anion to produce a second volatile compound; and releasing the treated sample from the carrier medium, wherein when the first and the second volatile compounds are produced, the releasing step releases at least one of the first and second volatile compounds from the carrier medium.