(1-羟基-1H-吲哚-3-基)乙酸 | 3289-81-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 中文名称: (1-羟基-1H-吲哚-3-基)乙酸
• 中文别名: 氨甲酸,(1-乙基-3-丁烯基)-,乙基酯(9CI)
• 英文名称: N-Hydroxy-3-hydroxycarbonylmethyl-indole
• 英文别名: (1-hydroxy-indol-3-yl)-acetic acid；(1-Hydroxy-indol-3-yl)-essigsaeure；2-(1-Hydroxy-1H-indol-3-yl)acetic acid；2-(1-hydroxyindol-3-yl)acetic acid
• CAS: 3289-81-4
• 化学式: C₁₀H₉NO₃
• mdl: MFCD09751730
• 分子量: 191.186
• InChiKey: LPNFRIOADLYECN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  62.5
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 海关编码：
  2933990090

文献信息

• MOLECULES FOR DIAGNOSTICS AND THERAPEUTICS
  申请人：Incyte Genomics, Inc.

  公开号：EP1224275A2

  公开（公告）日：2002-07-24
• [EN] MOLECULES FOR DIAGNOSTICS AND THERAPEUTICS<br/>[FR] MOLECULES POUR LE DIAGNOSTIC ET LA THERAPEUTIQUE
  申请人：INCYTE GENOMICS INC

  公开号：WO2001021836A2

  公开（公告）日：2001-03-29

  The present invention provides purified human polynucleotides for diagnostics and therapeutics (dithp). Also encompassed are the polypeptides (DITHP) encoded by dithp. The invention also provides for the use of dithp, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing dithp for the expression of DITHP. The invention additionally provides for the use of isolated and purified DITHP to induce antibodies and to screen libraries of compounds and the use of anti-DITHP antibodies in diagnostic assays. Also provided are microarrays containing dithp and methods of use.