(2-羟基乙基)二甲基铵乳酸盐 | 56669-87-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羟基酸及其衍生物
• 中文名称: (2-羟基乙基)二甲基铵乳酸盐
• 英文名称: 2-hydroxyethyl dimethyl ammonium lactate
• 英文别名: N,N-dimethyl ethanolamine lactate；2-Hydroxyethyl(dimethyl)azanium;2-hydroxypropanoate；2-hydroxyethyl(dimethyl)azanium;2-hydroxypropanoate
• CAS: 56669-87-5
• 化学式: C₃H₆O₃*C₄H₁₁NO
• 分子量: 179.216
• InChiKey: QFQMQSNDWYRIAG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.01
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  81
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  N,N-二甲基乙醇胺 、 乳酸 以 甲醇 为溶剂， 反应 24.0h， 生成 (2-羟基乙基)二甲基铵乳酸盐
  参考文献：
  名称：

  Dual functions of N,N-dimethylethanolamnium-based ionic liquids for the Knoevenagel reactions at room temperature

  摘要：

  In this work, the hydrogen bond formation ability of cation and anion of the ILs was determined by using the solvatochromic method and was found to be responsible for their catalytic activity in the Knoevenagel reactions. The enhancement in the hydrogen bond donor ability of the cations and the hydrogen bond acceptor ability of the anions can both lead to the increase in the catalytic activity of the ILs. From the proposed reaction mechanism, it was deduced that the cations of the ILs can form hydrogen bond with aldehyde to activate the C=O bond as electrophile, and the anions of the ILs can promote active methylene compound to produce carboanion as nucleophile, showing dual function activation effect in the catalytic processes. In addition, the optimized N,N-dimethylethanolamnium acetate as dual function activator for the Koevenagel reactions benefits from wide substrates tolerance, ambient reaction temperature, easy work-up procedure, and easy reuse of the IL. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.cattod.2012.06.006

文献信息

• Ionic Liquids
  申请人：Walker Adam John

  公开号：US20080221361A1

  公开（公告）日：2008-09-11

  The invention provides ionic liquids and processes for their preparation. The liquids may either comprise a cation of the formula (I); N + HR 1 R 2 R 3 (I) wherein R 1 is a group —R 4 —O—R 5 ; R 2 and R 3 are each independently either hydrogen or hydrocarbyl, R 2 and R 3 may be joined together with the N to form a heterocyclic group; R 4 is a divalent hydrocarbyl radical; and R 5 is hydrocarbyl; or a cation of the formula (II), N+HR6R7R8 (II) wherein R 6 is an alkanolyl group; R 7 is a hydrocarbyl group; and R 8 is either hydrogen or hydrocarbyl, or R 7 and R 8 may be joined together with the N to form a heterocyclic group.

  本发明提供了离子液体及其制备方法。这些液体可以包括公式（I）的阳离子; N+HR1R2R3（I），其中R1是一个基团-R4-O-R5; R2和R3分别是氢或烃基，R2和R3可以与N结合形成杂环基团; R4是一个二价的烃基基团; R5是烃基; 或者是公式（II）的阳离子，N+HR6R7R8（II），其中R6是烷基醇基团; R7是烃基基团; R8是氢或烃基，或者R7和R8可以与N结合形成杂环基团。
• Ionic liquids comprising nitrogen containing cations
  申请人：Innovia Films Limited

  公开号：EP2322497A1

  公开（公告）日：2011-05-18

  The present invention relates to ionic liquid comprising an anion and a cation wherein the cation is a primary, secondary or tertiary ammonium ion containing a protonated nitrogen atom.

  本发明涉及由阴离子和阳离子组成的离子液体，其中阳离子是含有质子化氮原子的一级、二级或三级铵离子。
• Low temperature aminoplast curable cationic electrodepositable coating compositions
  申请人：PPG INDUSTRIES, INC.

  公开号：EP0125577B1

  公开（公告）日：1987-11-04
• ELEKTRISCH ABSCHEIDBARES ÜBERZUGSMITTEL
  申请人：BASF Coatings Aktiengesellschaft

  公开号：EP0859816B1

  公开（公告）日：2002-05-08
• DEANOL OR DERIVATIVES FOR THE TREATMENT OF SKIN IMPAIRMENTS AND BALDNESS
  申请人：Ghisalberti, Carlo

  公开号：EP1242044A2

  公开（公告）日：2002-09-25