(2-羟基乙基)马来酸氢酯 | 26560-94-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: (2-羟基乙基)马来酸氢酯
• 英文名称: maleic acid mono-(2-hydroxy-ethyl ester)
• 英文别名: Maleinsaeure-mono-(2-hydroxy-aethylester)；(ethylene glycol) maleate；(2-Hydroxyethyl) hydrogen maleate；(Z)-4-(2-hydroxyethoxy)-4-oxobut-2-enoic acid
• CAS: 26560-94-1
• 化学式: C₆H₈O₅
• 分子量: 160.127
• InChiKey: MAIIXYUYRNFKPL-UPHRSURJSA-N

物化性质

• 沸点：
  248.5°C (estimate)
• 密度：
  1.2564 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  83.8
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  马来酸酐 、 乙二醇 生成 (2-羟基乙基)马来酸氢酯
  参考文献：
  名称：

  Uschakow et al., Zhurnal Prikladnoi Khimii, 1959, vol. 32, p. 667,670, 671; engl. Ausg. S. 697, 700

  摘要：

  DOI：

文献信息

• MONOMER COMPOSITION CONTAINING UNSATURATED POLYALKYLENE GLYCOL ETHER-BASED MONOMER, METHOD FOR PRODUCING COMPOSITION THEREOF, POLYMER OBTAINED USING COMPOSITION THEREOF, AND METHOD FOR PRODUCING POLYMER THEREOF
  申请人：Kawabata Hiroshi

  公开号：US20130184420A1

  公开（公告）日：2013-07-18

  To provide a monomer composition containing an unsaturated polyalkylene glycol ether-based monomer and having excellent stability. Provided is a monomer composition containing an unsaturated polyalkylene glycol ether-based monomer represented by the following chemical formula (1): YO(R 1 O) n R 2 (1) [in the formula, Y represents an alkenyl group having 2 to 7 carbon atoms; R 1 O represents one or two or more types of oxyalkylene groups having 2 to 18 carbon atoms; n represents an average addition mole number of oxyalkylene groups and is a number of 5 to 500; and R 2 represents a hydrogen atom or a hydrocarbon group having 1 to 30 carbon atoms], an organic acid, and water, and having a pH of 4 to 13.

  提供一种含有不饱和聚烯醚基单体并具有优异稳定性的单体组合物。提供的单体组合物包含以下化学式（1）所表示的不饱和聚烯醚基单体：YO(R1O)nR2（1）[在该式中，Y表示具有2至7个碳原子的烯基基团；R1O表示具有2至18个碳原子的一种或两种或更多种氧烷基团；n表示氧烷基团的平均加入摩尔数，为5至500之间的数字；R2表示氢原子或具有1至30个碳原子的碳氢基团]，有机酸和水，并且具有pH值为4至13。
• Solubilization and Targeted Delivery of Drugs With Self-Assembling Amphiphilic Polymers
  申请人：Diwan Anil

  公开号：US20100260743A1

  公开（公告）日：2010-10-14

  There are provided amphiphilic biodegradable copolymers comprising a hydrophilic backbone with pendant aliphatic groups as the hydrophobic component. The polymers form nanoscale molecular aggregates in aqueous environments, which have hydrophobic interiors that are capable of solubilizing insoluble organic compounds such as drugs, vitamins, dyes, and imaging agents. The polymers optionally feature reactive functional groups that provide attachment points for antibodies, ligands, and other targeting moieties useful for the targeted delivery of drugs and imaging agents.

  提供的两性可降解共聚物包括具有羟基亲水骨架和作为疏水组分的脂肪族侧链的共聚物。这些聚合物在水性环境中形成纳米级分子聚集体，具有疏水内部，能够溶解不溶于水的有机化合物，如药物、维生素、染料和成像剂。这些聚合物可选择性地具有反应性功能基团，提供与抗体、配体和其他靶向基团的结合点，有助于药物和成像剂的靶向传递。
• SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTI-CANCER AGENTS
  申请人：Diwan Anil R.

  公开号：US20100239659A1

  公开（公告）日：2010-09-23

  The invention provides amphiphilic biocompatible copolymers which have a hydrophilic backbone and pendant hydrophobic groups. The polymers form nanoscale molecular aggregates in aqueous environments, which have hydrophobic interiors within which anticancer drugs may be solubilized. The polymers optionally feature attached antibodies, receptor ligands, and other targeting moieties which mediate adherence of the drug-carrying aggregates to targeted cancer cells.

  本发明提供了一种两性亲水的生物相容性共聚物，其具有亲水性骨架和挂链疏水基团。这些聚合物在水性环境中形成纳米级分子聚集体，其中具有疏水性内部，可在其中溶解抗癌药物。这些聚合物可选地具有连接的抗体、受体配体和其他靶向基团，这些基团介导药物携带聚集体与靶向癌细胞的附着。
• ADHESIVE COMPOSITION
  申请人：ZEON CORPORATION

  公开号：US20150225618A1

  公开（公告）日：2015-08-13

  An adhesive composition containing a latex of a highly saturated nitrile rubber (A) which has α,β-ethylenically unsaturated nitrile monomer units 10 to 55 wt %, conjugated diene monomer units 25 to 89 wt %, and α,β-ethylenically unsaturated dicarboxylic acid monoester monomer units 1 to 20 wt % and has an iodine value of 120 or less and a polyvalent amine compound (B).

  一种黏合剂组合物，包含高度饱和丙烯腈橡胶（A）的乳液，其中α，β-乙烯基不饱和丙烯腈单体单位占10至55重量％，共轭二烯单体单位占25至89重量％，α，β-乙烯基不饱和二羧酸单酯单体单位占1至20重量％，并且具有碘值不超过120和多价胺化合物（B）。
• PASTE RESIN
  申请人：Allnex Austria GmbH

  公开号：US20150344720A1

  公开（公告）日：2015-12-03

  The invention relates to a paste resin A which is a mixture of at least two acrylic copolymer resins A, wherein the acrylic copolymer resin A1 comprises at least one basic acrylic comonomer, and the acrylic copolymer resin A2 comprises at least one acidic acrylic comonomer, and a method of use thereof for formulating both water-borne and solvent-borne tinted paints with a wide variety of pigments.

  本发明涉及一种粘合树脂A，它是至少两种丙烯酸共聚物树脂A的混合物，其中丙烯酸共聚物树脂A1包括至少一种碱性丙烯酸共聚单体，丙烯酸共聚物树脂A2包括至少一种酸性丙烯酸共聚单体，并且提供了一种使用该粘合树脂制备水性和溶剂型着色涂料的方法，该涂料可以使用多种颜料。