(2R)-2-氨基-3-(2,2-二氯乙烯基硫基)丙酸 | 3326-09-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: (2R)-2-氨基-3-(2,2-二氯乙烯基硫基)丙酸
• 英文名称: 3-[(2,2-Dichlorovinyl)thio]-L-alanine
• 英文别名: (2R)-2-amino-3-(2,2-dichloroethenylsulfanyl)propanoic acid
• CAS: 3326-09-8
• 化学式: C₅H₇Cl₂NO₂S
• 分子量: 216.08
• InChiKey: HTUPGSGHOGPTAF-VKHMYHEASA-N

物化性质

• 沸点：
  311.1±42.0 °C(Predicted)
• 密度：
  1.544±0.06 g/cm3(Predicted)
• 溶解度：
  甲醇

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  88.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Use of ascorbic acid and salts of ascorbic acid to promote cell repair and regeneration after injury
  申请人：——

  公开号：US20020019372A1

  公开（公告）日：2002-02-14

  Ascorbic acid is a known vitamin and antioxidant. The present invention demonstrated that ascorbic acid is a strong promoter of cell repair and regeneration after injury. The mechanism by which ascorbic acid produces this effect is not through its known antioxidant properties. The present invention thus provides a new medical use for ascorbic acid in that ascorbic acid or its salts can be used as a drug following injury to promote cell repair and regeneration, and ultimately return of normal organ function. In addition, ascorbic acid or its salts could be given prior to a planned injury (e.g. surgery) to enhance cell repair and regeneration.

  抗坏血酸是一种已知的维生素和抗氧化剂。本发明证明，抗坏血酸是损伤后细胞修复和再生的强大促进剂。抗坏血酸产生这种作用的机制并非通过其已知的抗氧化特性。因此，本发明为抗坏血酸提供了一种新的医疗用途，即抗坏血酸或其盐类可在损伤后作为药物使用，以促进细胞修复和再生，并最终恢复正常的器官功能。此外，抗坏血酸或其盐类还可在计划的损伤（如手术）之前给予，以促进细胞修复和再生。
• [EN] USE OF ASCORBIC ACID AND SALTS OF ASCORBIC ACID TO PROMOTE CELL REPAIR AND REGENERATION AFTER INJURY<br/>[FR] UTILISATION D'ACIDE ASCORBIQUE ET DE SELS D'ACIDE ASCORBIQUE POUR AMELIORER LA REPARATION ET LA REGENERATION CELLULAIRES POST-LESIONNELLES
  申请人：UNIV ARKANSAS

  公开号：WO2002001954A1

  公开（公告）日：2002-01-10

  Ascorbic acid is known vitamin and antioxidant. The present invention demonstrated that ascorbic acid is a strong promoter of cell repair and regeneration after injury. The mechanism by which ascorbic acid produces this effect is not through its known antioxidan properties. The present invention thus provides a new medical use for ascorbic acid in that ascorbic acid or its salts can be used as a drug following injury to promote cell repair and regeneration, and ultimately return of normal organ function. In addition, ascorbic acid or its salts could be given prior to a planned injury (e.g. surgery) to enhance cell repair and regeneration.