(4-甲氧基苯基)甲基月桂酸酯 | 93980-79-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: (4-甲氧基苯基)甲基月桂酸酯
• 英文名称: 4-methoxybenzyl dodecanoate
• 英文别名: (4-Methoxyphenyl)methyl laurate；(4-methoxyphenyl)methyl dodecanoate
• CAS: 93980-79-1
• 化学式: C₂₀H₃₂O₃
• 分子量: 320.472
• InChiKey: DRMAPFJISUWUEF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  23
• 可旋转键数：
  14
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  月桂酸 、 2,2,2-三氯代亚氨逐乙酸-4-甲氧基苄酯 以 二氯甲烷 为溶剂， 反应 24.0h， 以89%的产率得到(4-甲氧基苯基)甲基月桂酸酯
  参考文献：
  名称：

  使用4-甲氧基苄基-2,2,2-三氯乙亚胺酸酯自发形成PMB酯

  摘要：

  在不存在酸催化剂的情况下，用4-甲氧基苄基-2,2,2-三氯乙亚氨酸酯将羧酸转化为相应的4-甲氧基苄基（PMB）酯。该操作简单的步骤是形成PMB酯的高效方法。羧酸本身以优异的产率（72–99％）促进了反应。与其他酰亚胺化合物提供较低收率的立体受阻羧酸，与反应性更强的PMB亚氨酸酯以较高的收率进行酯化。在带有α-立体中心的羧酸的情况下未观察到外消旋化，并且对于Z-α，β-不饱和酸未观察到异构化。因此，该方法可用于复杂或敏感底物的酯化反应中，其中更常见的技术会导致分解。

  DOI：

  10.1016/j.tetlet.2014.01.097

文献信息

• REVERSIBLY THERMOCHROMIC COMPOSITION
  申请人：Kabushiki Kaisha Pilot Corporation

  公开号：EP2772523A1

  公开（公告）日：2014-09-03

  [Object] To provide a reversibly thermochromic composition free from accidental discoloration by heat conducting from the opposite side writing surface or by self-heating due to quick writing; and also to provide a solid writing material and a writing ink composition comprising that composition. [Means to solve the problem] A reversibly thermochromic composition comprising a combination of: (a) a reversibly thermochromic component capable of being discolored or decolored by heat and (b) a component for controlling heat conducting to the reversibly thermochromic component; and also a solid writing material and a writing ink composition comprising that composition.

  [目的]提供一种可逆热致变色组合物，该组合物不会因反面书写面的热传导或快速书写导致的自热而意外变色；还提供一种固体书写材料和包含该组合物的书写墨水组合物。 [解决问题的方法] 一种可逆热致变色组合物，由以下物质组合而成：(a) 能够受热变色或脱色的可逆热致变色成分和 (b) 用于控制热量传导至可逆热致变色成分的成分；以及包含该成分的固体书写材料和书写墨水组合物。
• Thermochromic coloring color-memory composition and thermochromic coloring color-memory microcapsule pigment containing the same
  申请人：Ono Yoshiaki

  公开号：US20060112851A1

  公开（公告）日：2006-06-01

  A thermochromic coloring color-memory composition comprising a homogeneous solubilized mixture of (A) an electron donative coloring organic compound, (B) an electron accepting compound and (C) a compound represented by the specific formula as a reaction medium which controls color reactions of the components (A) and (B).

  一种热致变色着色-颜色记忆组合物，由以下物质的均相溶解混合物组成：(A) 一种电子供体着色有机化合物；(B) 一种电子受体化合物；(C) 一种由特定式子表示的化合物，作为反应介质，可控制组分(A)和(B)的颜色反应。
• Hydroalkylation of Olefins To Form Quaternary Carbons
  作者：Samantha A. Green、Tucker R. Huffman、Ruairí O. McCourt、Vincent van der Puyl、Ryan A. Shenvi

  DOI：10.1021/jacs.9b02844

  日期：2019.5.15

  Metal-hydride hydrogen atom transfer (MHAT) functionalizes alkenes with predictable branched (Markovnikov) selectivity. The breadth of these transformations has been confined to pi-radical traps; no sp(3) electrophiles have been reported. Here we describe a Mn/Ni dual catalytic system that hydroalkylates unactivated olefins with unactivated alkyl halides, yielding aliphatic quaternary carbons.
• Immobilization of lipase on biocompatible co-polymer of polyvinyl alcohol and chitosan for synthesis of laurate compounds in supercritical carbon dioxide using response surface methodology
  作者：Kirtikumar C. Badgujar、Bhalchandra M. Bhanage

  DOI：10.1016/j.procbio.2015.04.019

  日期：2015.8

  Biocompatible co-polymer matrix has great importance for enzyme immobilization and subsequent bio-catalytic applications to synthesize important organic moieties. Citronellyl laurate is a fatty-acid-ester having pleasant fruity aroma and widely used as/in emulsifier, lubricant in textile, paint or ink-additives, surfactants, perfumery and food-flavouring ingredient. In present study, Burkholderia cepacia lipase (BCL) was immobilized on biodegradable co-polymer of chitosan (CHI) and polyvinyl alcohol (PVA). The synthesized bio-catalyst PVA:CHI:BCL (6:4:2.5)} was characterized by SEM, TGA, lipase assay and protein-content analysis. This biocatalyst was applied to synthesize citronellyl laurate in supercritical carbon-dioxide (SC-CO2) using response surface methodology with five-factor-three-level Box-Behnken-design to optimize reaction parameters (citronellol: 8.5 mmol; vinyl laurate: 19.87 mmol; biocatalyst: 175.6 mg; temperature: 46.02 degrees C; pressure: 8.81 MPa) which provided 94 +/- 1.52% yield. The protocol is extended to synthesize various important 12 laurate compounds with excellent yield (90-98%) and noteworthy recyclability (upto studied 5 recycles). Interestingly, immobilized PVA/CHI/lipase biocatalyst showed 4-fold higher bio-catalytic activity than free lipase in SC-CO2. Moreover, the biocatalyst activity assessment study showed remarkable activity-stability of immobilized biocatalyst in SC-CO2 media as compared to free enzyme. Thus, present protocol demonstrated potential biocatalytic applications for synthesis of important laurate compounds with excellent recyclability in SC-CO2 as greener biocatalyst and reaction medium. (C) 2015 Elsevier Ltd. All rights reserved.
• Reversible thermochromic composition and microcapsules containing the same
  申请人：THE PILOT INK CO., LTD.

  公开号：EP1657073B1

  公开（公告）日：2008-02-27