(4-甲酰基-2-甲氧基苯基)十三烷酸酯 | 765298-71-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 中文名称: (4-甲酰基-2-甲氧基苯基)十三烷酸酯
• 英文名称: Tridecanoic acid 4-formyl-2-methoxy-phenyl ester
• 英文别名: Tridecanoic acid, 4-formyl-2-methoxyphenyl ester；(4-formyl-2-methoxyphenyl) tridecanoate
• CAS: 765298-71-3
• 化学式: C₂₁H₃₂O₄
• 分子量: 348.483
• InChiKey: VKGXCDKSKWQZCD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  25
• 可旋转键数：
  15
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,2-丙二醇 、 (4-甲酰基-2-甲氧基苯基)十三烷酸酯 在 FIBAN K-1 cation exchanger 作用下， 以 苯 为溶剂， 以80%的产率得到
  参考文献：
  名称：

  Synthesis of 1,3-dioxolanes from substituted benzaldehydes of the vanillin series

  摘要：

  Condensation of substituted benzaldehydes of the vanillin series with propane-1,2-diol and 3-chloropropane-1,2-diol in boiling benzene in the presence of FIBAN K-1 sulfonated cation exchanger as catalyst gave the corresponding substituted 1,3-dioxolanes.

  DOI：

  10.1134/s1070363212090149
• 作为产物：
  描述：

  十三酸 在 吡啶 、 氯化亚砜 作用下， 以 二氯甲烷 、 苯 为溶剂， 反应 1.0h， 生成 (4-甲酰基-2-甲氧基苯基)十三烷酸酯
  参考文献：
  名称：

  Preparative Synthesis of Vanillin and Vanillal Alkanoates

  摘要：

  制备香草醛及其烷酸酯的工艺流程被开发出来。

  DOI：

  10.1007/s11167-005-0242-y

文献信息

• Synthesis of 3,4-Substituted Phenylmethylene-(2-carboxyphenyl)amines and Their Antitumor Activity
  作者：E. A. Dikusar、N. G. Kozlov、V. I. Potkin、V. M. Zelenkovskii、A. A. Malama、S. V. Dubovik

  DOI：10.1007/s10600-005-0112-0

  日期：2005.3

  Previously unknown azomethines 3a-z and 4a-j were prepared in methanol by condensation of anthranilic acid 1 with vanillin, vanillal, and esters of these compounds 2.

  通过将蚁酸 1 与香兰素、香草醛以及这些化合物的酯 2 缩合，在甲醇中制备出了之前未知的偶氮甲烷 3a-z 和 4a-j。
• Vanillin Esters of Aliphatic Acids in the Synthesis of 4,7-Phenanthroline Derivatives
  作者：N. G. Kozlov、K. N. Gusak、A. B. Tereshko、E. A. Dikusar

  DOI：10.1023/b:rujo.0000043718.23826.ac

  日期：2004.5

  Condensation of vanillin esters of aliphatic acids with 6-aminoquinoline and cyclic c-diketones (1,3-cyclohexanedione and dimedone) afforded new 2-methoxy-4-(11-oxo-7,8,9,10,11,12-hexahydrobenzo[b][4,7]phenanthrolin-12-yl)phenyl esters of carboxylic acids.
• Synthesis of 2-R-1,3-dioxanes, derivatives of functionally substituted aldehydes of vanillin series
  作者：E. A. Dikusar、V. I. Potkin、T. D. Zvereva、N. A. Zhukovskaya、S. K. Petkevich、A. S. Pavlyuchenkova、M. Yu. Murashova、A. P. Polikarpov、A. A. Shunkevich、A. P. Yuvchenko、R. M. Zolotar’

  DOI：10.1134/s1070428013020085

  日期：2013.2

  By the condensation of substituted aldehydes of vanillin series with 1,3-propanediol in boiling benzene in the presence of sulfo cation exchanger FIBAN K-1 as catalyst functionally 2-R-substituted 1,3-dioxanes were synthesized.
• Reaction of Long-Chain Vanillyl Esters with CH-Acids and 2-Naphthylamine
  作者：N. G. Kozlov、L. I. Basalaeva、E. A. Dikusar

  DOI：10.1023/b:conc.0000025473.93772.9e

  日期：2004.1

  The previously unknown 4-(alkyl-1-oxo-7,8,9,10,11,12-hexahydrobenzo[a]actidin-12-yl)- and 4-(alk-yl-],8'-dioxo-2,3,4,5,6,7,8,9-octahydro-]1H-xanthen-9-yl)-2-methoxyphenyl esters of aliphatic (C-5-C-7, C-12) carboxylic acids were synthesized via cascade heterocyclization of cyclohexane-1,3-dione and dimedone with 2-naphthylamine and long-chain vanillyl esters.
• Preparative synthesis of 4-hydroxy(alkyloyloxy, aryloyloxy)-3-methoxy(ethoxy)phenylmethylene(4-carboxyphenyl)amines
  作者：E. A. Dikusar、N. G. Kozlov、N. A. Zhukovskaya、V. I. Potkin、M. M. Ogorodnikova、V. M. Zelenkovskii

  DOI：10.1134/s1070428002120084

  日期：2006.2

  By reactions of vanillin, vanillal, and their esters with 4-aminobenzoic acid in methanol formerly unknown E-isomers of azomethines (Schiff's bases) were prepared.