(4S)-4-[(1R)-2-叠氮-1-(苄氧基)乙基]-2,2-二甲基-1,3-二氧戊环 | 1228077-93-7

• 物质功能分类: 化学试剂 - 有机试剂 - 叠氮
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: (4S)-4-[(1R)-2-叠氮-1-(苄氧基)乙基]-2,2-二甲基-1,3-二氧戊环
• 英文名称: (4S)-4-[(1R)-2-Azido-1-(benzyloxy)ethyl]-2,2-dimethyl-1,3-dioxolane
• 英文别名: (4S)-4-[(1R)-2-azido-1-phenylmethoxyethyl]-2,2-dimethyl-1,3-dioxolane
• CAS: 1228077-93-7
• 化学式: C14H19N3O3
• 分子量: 277.32
• InChiKey: YWANFIYHLHBBCF-OLZOCXBDSA-N

物化性质

• 密度：
  1.116 g/mL at 25 °C(lit.)
• 闪点：
  218 °F

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  20
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  42
• 氢给体数：
  0
• 氢受体数：
  5

安全信息

• 危险品标志：
  Xn
• 安全说明：
  S36
• 危险类别码：
  R22
• WGK Germany：
  3

文献信息

• Methods of generating nanoarrays and microarrays
  申请人：NAUTILUS BIOTECHNOLOGY, INC.

  公开号：US11203612B2

  公开（公告）日：2021-12-21

  The methods described herein provide a means of producing an array of spatially separated proteins. The method relies on covalently attaching each protein of the plurality of proteins to a structured nucleic acid particle (SNAP), and attaching the SNAPs to a solid support.

  本文所述方法提供了一种生产空间分离蛋白质阵列的方法。该方法将多个蛋白质中的每个蛋白质共价连接到结构化核酸颗粒（SNAP）上，并将 SNAP 连接到固体支持物上。
• METHODS OF GENERATING NANOARRAYS AND MICROARRAYS
  申请人：NAUTILUS BIOTECHNOLOGY, INC.

  公开号：US20210101930A1

  公开（公告）日：2021-04-08

  The methods described herein provide a means of producing an array of spatially separated proteins. The method relies on covalently attaching each protein of the plurality of proteins to a structured nucleic acid particle (SNAP), and attaching the SNAPs to a solid support.
• METHODS AND SYSTEMS FOR COMPUTATIONAL DECODING OF BIOLOGICAL, CHEMICAL, AND PHYSICAL ENTITIES
  申请人：NAUTILUS BIOTECHNOLOGY, INC.

  公开号：US20210390705A1

  公开（公告）日：2021-12-16

  The present disclosure provides systems and methods for detecting components of an array of biological, chemical, or physical entities. In an aspect, the present disclosure provides a method for detecting an array of biological, chemical, or physical entities, comprising: (a) using one or more light sensing devices, acquiring pixel information from sites in an array, wherein the sites comprise biological, chemical, or physical entities that produce light; (b) processing the pixel information to identify a set of regions of interest (ROIs) corresponding to the sites in the array that produce the light; (c) classifying the pixel information for the ROIs into a categorical classification from among a plurality of distinct categorical classifications, thereby producing a plurality of pixel classifications; and (d) identifying one or more components of the array of biological, chemical, or physical entities based at least in part on the plurality of pixel classifications.
• METHODS AND SYSTEMS FOR INTEGRATED ON-CHIP SINGLE-MOLECULE DETECTION
  申请人：Nautilus Biotechnology, Inc.

  公开号：US20220050049A1

  公开（公告）日：2022-02-17

  The present disclosure provides methods and systems for performing single-molecule detection using fabricated integrated on-chip devices. In an aspect, the present disclosure provides a method for on-chip detection of an array of biological, chemical, or physical entities, comprising: (a) providing an array of light sensing devices; (b) immobilizing the array of biological, chemical, or physical entities on a substrate of the array of light sensing devices; (c) exposing the array of biological, chemical, or physical entities to electromagnetic radiation sufficient to excite the array of biological, chemical, or physical entities, thereby producing an emission signal of the array of biological, chemical, or physical entities; (d) using the array of light sensing devices, acquiring pixel information of the emission signal of the array of biological, chemical, or physical entities without scanning the array of light sensing devices across the array of biological, chemical, or physical entities; and (d) detecting the array of biological, chemical, or physical entities based at least in part on the acquired pixel information.