Vitamin L2

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 核苷和核苷酸类似物
• 英文名称: Vitamin L2
• 英文别名: 1-(6-amino-purin-7-yl)-S-methyl-5-thio-1-deoxy-pentofuranose；2-(6-Aminopurin-7-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol
• 化学式: C₁₁H₁₅N₅O₃S
• 分子量: 297.338
• InChiKey: CORUJUWTKCXKFP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  145
• 氢给体数：
  3
• 氢受体数：
  8

文献信息

• Verwendung von 5'-Desoxy-5'-methylthioadenosin in hautkosmetischen Mitteln
  申请人：BASF AKTIENGESELLSCHAFT

  公开号：EP1273285A2

  公开（公告）日：2003-01-08

  Die vorliegende Erfindung betrifft die Verwendung von 5'-Desoxy-5'-methylthioadenosin in hautkosmetischen Mitteln zur Verbesserung des Hautbildes, derartige Mittel und ein Verfahren zur kosmetischen Behandlung der Haut.

  本发明涉及 5'-脱氧-5'-甲硫基腺苷在改善皮肤外观的皮肤美容组合物中的使用、这类组合物以及一种皮肤美容方法。
• Method and apparatus for inactivation of biological contaminats using photosensitizers
  申请人：CaridianBCT Biotechnologies, LLC

  公开号：EP2174669A1

  公开（公告）日：2010-04-14

  Methods and apparatuses are provided for inactivation of microorganisms in fluids or on surfaces. Preferably the fluids contain blood or blood products and comprise biologically active proteins. Preferred methods include the steps of adding an effective, non-toxic amount of an endogenous photosensitizer to a fluid and exposing the fluid to photoradiation sufficient to activate the endogenous photosensitizer whereby microorganisms are inactivated. Other fluids, including juices, water and the like, may also be decontaminated by these methods as may surfaces of foods, animal carcasses, wounds, food preparation surfaces and bathing and washing vessel surfaces. Alloxazines and K- and L- vitamins are among the preferred photosensitizers. Systems and apparatuses for flow-through and batch processes are also provided for decontamination of such fluids using photosensitizers.

  提供了灭活液体或表面微生物的方法和装置。这些液体最好含有血液或血液制品，并包含生物活性蛋白质。优选的方法包括以下步骤：在流体中加入有效、无毒的内源性光敏剂，并将流体暴露于足以激活内源性光敏剂的光辐射中，从而灭活微生物。其他流体，包括果汁、水等，也可以通过这些方法进行净化，如食品表面、动物尸体、伤口、食品制备表面以及沐浴和清洗容器表面。烯噁嗪类和 K- 及 L- 维生素是首选的光敏剂。此外，还提供了用于流动和批量工艺的系统和装置，以便使用光敏剂对这些液体进行净化。
• Use of 5'-deoxy-5'-methylthioadenosine in skin cosmetic compositions
  申请人：——

  公开号：US20030068349A1

  公开（公告）日：2003-04-10

  The present invention relates to the use of 5′-deoxy-5′-methylthioadenosine in skin cosmetic compositions for improving the appearance of the skin, to such compositions and to a method for the cosmetic treatment of the skin.

  本发明涉及 5′-脱氧-5′-甲硫基腺苷在改善皮肤外观的皮肤美容组合物中的使用，涉及这种组合物和一种皮肤美容方法。
• PREPARATION OF VACCINES USING A PHOTOSENSITIZER AND LIGHT
  申请人：Goodrich P. Raymond

  公开号：US20070059791A1

  公开（公告）日：2007-03-15

  Methods are provided for treating a vaccine containing infectious particles which may be viral, bacterial, and/or cellular in nature. Preferred methods include the steps of adding an effective, non-toxic amount of an endogenous photosensitizer to the fluid and exposing the fluid to photoradiation sufficient to inactivate the infectious particles but not enough to damage the antigenic characteristics of the infectious particles.
• Preparation of Vaccines Using Photosensitizers and Light
  申请人：GOODRICH P. Raymond

  公开号：US20070212379A1

  公开（公告）日：2007-09-13

  Methods are provided for treating a vaccine containing infectious particles which may be viral, bacterial, and/or cellular in nature. Preferred methods include the steps of adding an effective, non-toxic amount of an endogenous photosensitizer to the fluid and exposing the fluid to photoradiation sufficient to inactivate the infectious particles but not enough to damage the antigenic characteristics of the infectious particles.