7,10-Diazatetracyclo[8.6.1.05,17.011,15]heptadeca-1(17),2,4-triene

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯二氮卓类
• 英文名称: 7,10-Diazatetracyclo[8.6.1.05,17.011,15]heptadeca-1(17),2,4-triene
• 化学式: C₁₅H₂₀N₂
• 分子量: 228.33
• InChiKey: PYMPWKOVVSCRAP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• 1,2,3,4,7,8-Hexahydro-6H-[1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents
  申请人：Wyeth

  公开号：US20040019040A1

  公开（公告）日：2004-01-29

  Compounds of Formula I or a pharmaceutically acceptable salt thereof are provided: 1 where R 1 through R 7 are defined herein. The compounds of Formula I are 5HT2c agonists or partial agonists, and are useful for treating a variety of disorders.

  提供的是公式I的化合物或其药用可接受的盐： 1 其中R 1 至R 7 在此处定义。公式I的化合物是5HT2c激动剂或部分激动剂，并且对于治疗多种疾病是有用的。
• 1,2,3,4,7,8-Hexahydro-6H-[1,4]diazepino[6,7,1-ij] quinoline derivatives as antipsychotic and antiobesity agents
  申请人：Ramamoorthy Sivaramakrishnan P.

  公开号：US20060154920A1

  公开（公告）日：2006-07-13

  Compounds of Formula I or a pharmaceutically acceptable salt thereof are provided: where R 1 through R 7 are defined herein. The compounds of Formula I are 5HT2c agonists or partial agonists, and are useful for treating a variety of disorders.

  提供公式I或其药学上可接受的盐的化合物：其中R1至R7在此定义。公式I的化合物是5HT2c激动剂或部分激动剂，可用于治疗各种疾病。
• 1,2,3,4,7,8-HEXAHYDRO-6 i H /i - 1,4 DIAZEPINO 6,7 ,1- i 1J /i QUINOLINE DERIVATIVES AS ANTIPSYCHOTIC AND ANTI OBESITY AGENTS
  申请人：Wyeth

  公开号：EP1497294A1

  公开（公告）日：2005-01-19
• US7071185B2
  申请人：——

  公开号：US7071185B2

  公开（公告）日：2006-07-04
• [EN] 1,2,3,4,7,8-HEXAHYDRO-6H-[1,4]DIAZEPINO[6,7,1-1J]QUINOLINE DERIVATIVES AS ANTIPSYCHOTIC AND ANTIOBESITY AGENTS<br/>[FR] DERIVES DE 1,2,3,4,7,8-HEXAHYDRO-6H-[1,4]DIAZEPINO[6,7,1-IJ]QUINOLINE SERVANT D'AGENTS ANTIPSYCHOTIQUES ET ANTI-OBESITE
  申请人：WYETH CORP

  公开号：WO2003091251A1

  公开（公告）日：2003-11-06

  Compounds of formula I or a pharmaceutically acceptable salt thereof are provided where R1 through R7 are defined herein. The compounds of formula I are 5HT2c agonists or partial agonists, and are useful for treating a variety of disorders.