2-[2-[2-[2-(Carboxymethylamino)ethylamino]ethylamino]ethylamino]acetic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[2-[2-[2-(Carboxymethylamino)ethylamino]ethylamino]ethylamino]acetic acid
• 化学式: C₁₀H₂₂N₄O₄
• 分子量: 262.31
• InChiKey: WNIBCFTVQSCFKW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -6.9
• 重原子数：
  18
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  123
• 氢给体数：
  6
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  2-[2-[2-[2-(Carboxymethylamino)ethylamino]ethylamino]ethylamino]acetic acid 、 无水氯化铜 生成 copper;2-[2-[2-[2-(carboxylatomethylamino)ethylamino]ethylamino]ethylamino]acetate
  参考文献：
  名称：

  JACKSON, GRAHAM E.;KELLY, MARK J., J. CHEM. SOC. DALTON TRANS,(1989) N2, C. 2429-2433

  摘要：

  DOI：

文献信息

• Efficacy enhancers for germicides
  申请人：ETHICON, INC.

  公开号：EP1547621A2

  公开（公告）日：2005-06-29

  Disclosed herein are germicidal compositions and methods of using the germicidal compositions for disinfection and sterilization. In one aspect, a germicidal composition includes a germicidal dialdehyde and an efficacy enhancing halide salt to enhance the efficacy of the dialdehyde. One such composition may include water, phthalaldehyde, and an alkali metal halide salt to enhance the efficacy of the phthalaldehyde. In another aspect, a germicidal composition may include a carbonated germicidal solution containing dissolved phthalaldehyde. A method of forming the carbonated solution may include introducing carbon dioxide into the composition.

  本文公开了杀菌组合物和使用杀菌组合物进行消毒和灭菌的方法。一方面，杀菌组合物包括杀菌二甲醛和增强二甲醛功效的卤化盐。其中一种组合物可包括水、邻苯二甲酸醛和碱金属卤化盐，以增强邻苯二甲酸醛的功效。另一方面，杀菌组合物可以包括含有溶解酞醛的碳酸杀菌溶液。形成碳酸化溶液的方法可包括将二氧化碳引入组合物中。
• Germicidal compositions comprising phthalaldehyde
  申请人：ETHICON, INC.

  公开号：EP1547620A2

  公开（公告）日：2005-06-29

  Disclosed herein are germicidal compositions, kits, methods for preparing the germicidal compositions, and methods of using the compositions for disinfection or sterilization. In one aspect, a solid composition may include a solid having water solubility greater than phthalaldehyde, and a germicide diluted in the solid. In another aspect, a kit for preparing a germicide solution may include a germicide, an enhancer for the germicide, and at least two compartments to contain the germicide and the enhancer. In yet another aspect, an apparatus may be used to prepare a germicidal solution. The apparatus may include a first port to receive a first composition including a germicidally effective compound, a second port to receive a second composition including an enhancer for the germicidally effective compound, a source of water, and germicidal solution preparation logic to control preparation of the germicidal solution from the first and the second compositions and the water.

  本文公开了杀菌组合物、试剂盒、制备杀菌组合物的方法以及使用组合物进行消毒或灭菌的方法。一方面，固体组合物可包括水溶性大于酞醛的固体和稀释在固体中的杀菌剂。另一方面，制备杀菌剂溶液的试剂盒可包括杀菌剂、杀菌剂增强剂以及至少两个用于容纳杀菌剂和增强剂的隔间。另一个方面，一种设备可用于制备杀菌溶液。该装置可包括用于接收包括杀菌有效化合物的第一组合物的第一端口、用于接收包括杀菌有效化合物增强剂的第二组合物的第二端口、水源，以及用于控制从第一和第二组合物及水制备杀菌溶液的杀菌溶液制备逻辑。
• Kit and apparatus for preparing germicidal compositions comprising phthalaldehyde
  申请人：ETHICON, INC.

  公开号：EP1623725A2

  公开（公告）日：2006-02-08

  Disclosed herein are germicidal compositions, kits, methods for preparing the germicidal compositions, and methods of using the compositions for disinfection or sterilization. In one aspect, a solid composition may include a solid having water solubility greater than phthalaldehyde, and a germicide diluted in the solid. In another aspect, a kit for preparing a germicide solution may include a germicide, an enhancer for the germicide, and at least two compartments to contain the germicide and the enhancer. In yet another aspect, an apparatus may be used to prepare a germicidal solution. The apparatus may include a first port to receive a first composition including a germicidally effective compound, a second port to receive a second composition including an enhancer for the germicidally effective compound, a source of water, and germicidal solution preparation logic to control preparation of the germicidal solution from the first and the second compositions and the water.

  本文公开了杀菌组合物、试剂盒、制备杀菌组合物的方法以及使用组合物进行消毒或灭菌的方法。一方面，固体组合物可包括水溶性大于酞醛的固体和稀释在固体中的杀菌剂。另一方面，制备杀菌剂溶液的试剂盒可包括杀菌剂、杀菌剂增强剂以及至少两个用于容纳杀菌剂和增强剂的隔间。另一个方面，一种设备可用于制备杀菌溶液。该装置可包括用于接收包括杀菌有效化合物的第一组合物的第一端口、用于接收包括杀菌有效化合物增强剂的第二组合物的第二端口、水源，以及用于控制从第一和第二组合物及水制备杀菌溶液的杀菌溶液制备逻辑。
• Carbonated germicide with pressure control
  申请人：ETHICON, INC.

  公开号：EP1661587A1

  公开（公告）日：2006-05-31

  Disclosed herein are methods of sealing germicidal bicarbonate solutions in containers. In one aspect, a method may include introducing water, bicarbonate, and a germicide that is more stable at a pH of 7 than at a pH of 8 into a container, replacing at least a portion of a gas in the container with carbon dioxide, and sealing the container after said introducing the water, the bicarbonate, and the germicide, into the container, and after said replacing the gas. Sealed containers having the germicidal bicarbonate solutions are also disclosed.

  本文公开了在容器中密封碳酸氢盐杀菌溶液的方法。在一个方面，该方法可包括将水、碳酸氢盐和在 pH 值为 7 时比 pH 值为 8 时更稳定的杀菌剂引入容器，用二氧化碳取代容器中的至少一部分气体，以及在将水、碳酸氢盐和杀菌剂引入容器并取代气体后密封容器。还公开了装有碳酸氢盐杀菌溶液的密封容器。
• Distribution and preparation of germicidal compositions
  申请人：Wu S. Su-Syin

  公开号：US20050136118A1

  公开（公告）日：2005-06-23

  Disclosed herein are germicidal compositions, kits, methods for preparing the germicidal compositions, and methods of using the compositions for disinfection or sterilization. In one aspect, a solid composition may include a solid having water solubility greater than phthalaldehyde, and a germicide diluted in the solid. In another aspect, a kit for preparing a germicide solution may include a germicide, an enhancer for the germicide, and at least two compartments to contain the germicide and the enhancer. In yet another aspect, an apparatus may be used to prepare a germicidal solution. The apparatus may include a first port to receive a first composition including a germicidally effective compound, a second port to receive a second composition including an enhancer for the germicidally effective compound, a source of water, and germicidal solution preparation logic to control preparation of the germicidal solution from the first and the second compositions and the water.

  本文公开了杀菌组合物、试剂盒、制备杀菌组合物的方法以及使用组合物进行消毒或灭菌的方法。一方面，固体组合物可包括水溶性大于酞醛的固体和稀释在固体中的杀菌剂。另一方面，制备杀菌剂溶液的试剂盒可包括杀菌剂、杀菌剂增强剂以及至少两个用于容纳杀菌剂和增强剂的隔间。另一个方面，一种设备可用于制备杀菌溶液。该装置可包括用于接收包括杀菌有效化合物的第一组合物的第一端口、用于接收包括杀菌有效化合物增强剂的第二组合物的第二端口、水源，以及用于控制从第一和第二组合物及水制备杀菌溶液的杀菌溶液制备逻辑。