(Z)-2-吡啶基苯基酮肟 | 14178-30-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: (Z)-2-吡啶基苯基酮肟
• 英文名称: (Z)-2-pyridylphenyl ketoxime
• 英文别名: syn-phenyl-2-pyridylketoxime；(Z)-2-Benzoylpyridine oxime；phenyl-[2]pyridyl ketone-(Z)-oxime；Phenyl-[2]pyridyl-keton-(Z)-oxim；(Z)-phenyl-2-pyridinyl-methanone, oxime；phenyl 2-pyridyl ketone oxime；Phenyl(pyridin-2-yl)methanone oxime；(NZ)-N-[phenyl(pyridin-2-yl)methylidene]hydroxylamine
• CAS: 14178-30-4
• 化学式: C₁₂H₁₀N₂O
• 分子量: 198.224
• InChiKey: RSJDEVMJZLLAHS-OWBHPGMISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  45.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (Z)-2-吡啶基苯基酮肟 在 氯化亚砜 、 氯仿 作用下， 生成 N-phenyl-pyridine-2-carboximidoyl chloride
  参考文献：
  名称：

  苯基2-吡啶基酮（2-苯甲酰基吡啶）的肟的贝克曼重排。

  摘要：

  DOI：

  10.1021/ja01191a046
• 作为产物：
  描述：

  2-苄基吡啶 在 potassium permanganate 、 盐酸羟胺 、 sodium carbonate 作用下， 生成 (Z)-2-吡啶基苯基酮肟
  参考文献：
  名称：

  Tschitschibabin, Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1901, vol. 33, p. 701,702

  摘要：

  DOI：

文献信息

• Photoprotection compositions comprising chelating agents
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0313305A2

  公开（公告）日：1989-04-26

  The present invention involves photoprotective compositions which are useful for topical application to prevent damage to skin caused by acute or chronic exposure to ultraviolet light comprising chelating agents. Also involved are compositions comprising chelating agents together with anti-inflammatory agents, sunscreening agents, and/or radical scavenging agents. Methods for using such compositions to prevent damage to skin caused by acute or chronic exposure to ultraviolet light are also involved.

  本发明涉及光保护组合物，该组合物可用于局部使用，以防止皮肤因急性或慢性紫外线照射而受损，其中包含螯合剂。本发明还涉及包含螯合剂和消炎剂、防晒剂和/或自由基清除剂的组合物。还涉及使用此类组合物防止皮肤因急性或慢性紫外线照射而受损的方法。
• Porphyric insecticides
  申请人：The Board of Trustees for the University of Illinois

  公开号：EP0326835A1

  公开（公告）日：1989-08-09

  Insecticidal compositions comprising one or more compounds' selected from the group consisting of delta-aminolevulinic acid, inducers of delta aminolevulinic acid, and enhancers of delta-aminolevulinic acid conversion to photodynamic tetrapyrroles; and methods of making and using same.

  包含一种或多种选自δ-氨基乙酰丙酸、δ-氨基乙酰丙酸诱导剂和δ-氨基乙酰丙酸转化为光动力四吡咯的增强剂的化合物的杀虫组合物；以及其制造和使用方法。
• BENZOXAZINONE DERIVATIVE
  申请人：JAPAN TOBACCO INC.

  公开号：EP0569598A1

  公开（公告）日：1993-11-18

  A benzoxazinone derivative represented by general formula (I) or a pharmaceutically acceptable acid addition salt thereof, and an anti-inflammatory, a neutrophil infiltration inhibitor and a serine protease inhibitor each containing the derivative as an active ingredient, wherein R, R¹, R² and R³ may be the same or different from one another and each represents hydrogen or lower alkyl; A represents optionally halogenated phenyl, heterocycle or adamantyl; B represents hydrogen or optionally halogenated phenyl or heterocycle; U represents =CH-, =C= or =N-; V represents - O-, -CH₂-, =N-, -NH-, -CH= or a single bond; X represents -O-, =CH-, -CH₂- or a single bond; Y represents - CH₂-, -NH-, -O- or a single bond; Z represents -CO- or -CH₂-; and l represents an integer of 0 to 3. This compound has excellent activities of inhibiting serine protease, neutrotaxis, and infiltration of neutrophils into carragheenin-induced pneumocephalus.

  通式(I)代表的苯并恶嗪酮衍生物或其药学上可接受的酸加成盐，以及含有该衍生物作为活性成分的消炎药、中性粒细胞浸润抑制剂和丝氨酸蛋白酶抑制剂，其中R、R¹、R²和R³可以相同或彼此不同，各自代表氢或低级烷基；A 代表可选的卤代苯基、杂环或金刚烷基； B 代表氢或可选的卤代苯基或杂环； U 代表 =CH-、=C= 或 =N-；V 代表-O-、-CH₂-、=N-、-NH-、-CH= 或单键； X 代表-O-、=CH-、-CH₂- 或单键； Y 代表-CH₂-、-NH-、-O- 或单键； Z 代表-CO- 或-CH₂-； l 代表 0 至 3 的整数。该化合物在抑制丝氨酸蛋白酶、中性粒细胞减少和中性粒细胞浸润卡拉盖宁诱导的肺炎方面具有优异的活性。
• Method of producing crosslinkable silyl group-containing polyoxyalkylene polymers
  申请人：Kaneka Corporation

  公开号：EP1146062A1

  公开（公告）日：2001-10-17

  A method of producing a polyoxyalkylene polymer having at least one crosslinkable silyl group and at least one hydroxyl group in each molecule    which comprises treating a polyoxyalkylene polymer having at least one unsaturated group and at least one alcoholic hydroxyl group in each molecule and an impurity double metal cyanide complex as mixed therein with a metal-coordinating compound and adding a compound having a hydrogen-silicon bond and a crosslinkable silyl group in each molecule and a hydrosilylation catalyst to thereby carry out the hydrosilylation reaction.

  一种生产聚氧亚烷基聚合物的方法，其每个分子中至少有一个可交联的硅烷基和至少一个羟基 其中包括用金属配位化合物处理每个分子中至少有一个不饱和基团和至少一个醇羟基的聚氧亚烷基聚合物和其中混有的杂质双金属氰化物络合物 并在每个分子中加入具有氢硅键和可交联硅烷基的化合物以及氢硅烷化催化剂，从而进行氢硅烷化反应。
• Leave-in hair cosmetic compositions for enhancing volume
  申请人：——

  公开号：US20020034486A1

  公开（公告）日：2002-03-21

  Leave-in hair cosmetic compositions for enhancing hair volume comprise non-spherical microparticles exhibiting a mean particle size of less than about 100 &mgr;m in its longest dimension, a water-soluble or water-swellable polymer, and an aqueous carrier such that the combination of the polymer and the microparticles results in a film-forming network. Also disclosed are methods for enhancing hair volume, and more particularly for enhancing hair volume with leave-in aqueous cosmetic compositions which contain non-spherical microparticles of less than 100 &mgr;m in its longest dimension, a water-soluble or water-swellable polymer and an aqueous carrier. The disclosed compositions provide improved hair volume, body, bounce, fullness, springiness, and texture in addition to providing good hair conditioning and styling benefits. Fluid-encapsulated, flexible microspheres which exhibit a mean particle size of less than about 300 &mgr;m in diameter may also be included in the compositions.

  用于增加发量的免洗护发化妆品组合物包含平均粒径最长尺寸小于约 100 微米的非球形微颗粒、水溶性或水溶性聚合物以及水性载体，聚合物与微颗粒的结合可形成成膜网络。本发明还公开了增加发量的方法，尤其是使用免洗水性化妆品组合物增加发量的方法，该组合物含有最长尺寸小于 100 微米的非球形微颗粒、水溶性或水膨胀性聚合物和水性载体。所公开的组合物除了具有良好的护发和造型功效外，还能改善发量、发体、弹力、丰满度、弹性和质感。组合物中还可加入平均粒径小于约 300 微米的流体封装柔性微球。