3-(2-aminoethyl)-1H-indol-5-ol;2-(1H-imidazol-5-yl)ethanamine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 3-(2-aminoethyl)-1H-indol-5-ol;2-(1H-imidazol-5-yl)ethanamine
• 化学式: C15H21N5O
• 分子量: 287.36
• InChiKey: PLXWLWVPEBTRIZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.29
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  117
• 氢给体数：
  5
• 氢受体数：
  4

文献信息

• Artificial synapse chip
  申请人：——

  公开号：US20040224002A1

  公开（公告）日：2004-11-11

  Devices and methods are provided for administering a fluid to a neuronal site. The device comprises a reservoir, an aperture in fluid connection to the reservoir, and electrical means for moving to the fluid to or through the aperture. The electrical means may take the form of electroosmotic force, piezoelectric movement of a diaphragm or electrolysis of a solution. The electrical means may be external to the host, implanted in the host or may be photodiodes activated by light, particularly where the neuronal site is associated with the retina.

  提供了将流体注入神经元部位的装置和方法。该装置包括一个储液器、一个与储液器流体连通的孔，以及用于将流体移至或通过孔的电动装置。电动装置可采用电渗透力、膜片压电运动或溶液电解的形式。电子装置可以是宿主外部的，也可以是植入宿主体内的，还可以是由光激活的光电二极管，特别是在神经元部位与视网膜相关的情况下。
• Optically controlled microfluidic chip
  申请人：Palanker V. Daniel

  公开号：US20060116741A1

  公开（公告）日：2006-06-01

  An optically controlled microfluidic chip is provided for administering a fluid to a neuronal site. The chip is made of at least one unit or pixel, each of which constitutively emits fluid in the dark, and reduces emission of fluid in response to light. The individual pixels are capable of being individually controlled, thereby translating a spatial pattern of incident light into a spatial pattern of neuronal stimulation. Each pixel contains a housing, an aperture in the housing, and a reservoir containing fluid that is connected to the aperture. The aperture is designed to allow continuous emission of fluid from the reservoir through the aperture when the pixel is in the dark. Each pixel also includes an optical control, which reduces the emission of fluid from the reservoir through the aperture in response to light.

  提供了一种光学控制微流控芯片，用于向神经元部位注入液体。该芯片由至少一个单元或像素组成，每个单元或像素在黑暗中连续发射液体，在光照下减少液体发射。单个像素可单独控制，从而将入射光的空间模式转化为刺激神经元的空间模式。每个像素包含一个外壳、外壳上的一个孔和一个与孔相连的装有液体的储液器。开孔的设计目的是当像素处于黑暗状态时，贮液器中的液体能够通过开孔持续发射。每个像素还包括一个光学控制装置，该装置可在光照下减少贮液器中的流体通过光孔排出。
• IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN, INFLAMMATION AND SPASM
  申请人：OMEROS MEDICAL SYSTEMS, INC

  公开号：EP0799051A2

  公开（公告）日：1997-10-08
• METHODS AND SYSTEMS FOR USING VISUAL IMAGERY AND UTILITARIAN ARTICLES TO PROMOTE OR DEMONSTRATE EMOTIONAL AND/OR PHYSICAL RESPONSES
  申请人：Hawkes, Gary J.

  公开号：EP1454278A1

  公开（公告）日：2004-09-08
• ARTIFICIAL SYNAPSE CHIP
  申请人：The Board of Trustees of the Leland Stanford Junior University

  公开号：EP1694309A2

  公开（公告）日：2006-08-30