6-[2-(Cyclopenten-1-yl)pyrazolo[1,5-a]pyridin-3-yl]-2-propan-2-ylpyridazin-3-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡唑并吡啶类
• 英文名称: 6-[2-(Cyclopenten-1-yl)pyrazolo[1,5-a]pyridin-3-yl]-2-propan-2-ylpyridazin-3-one
• 化学式: C₁₉H₂₀N₄O
• 分子量: 320.4
• InChiKey: CYATZSJUPJXHSO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  50
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] PYRIDAZINONE COMPOUND AS ADENOSINE ANTAGONISTS<br/>[FR] COMPOSES DE PYRIDAZINONE UTILES COMME ANTAGONISTES DE L'ADENOSINE
  申请人：FUJISAWA PHARMACEUTICAL CO

  公开号：WO2003004494A1

  公开（公告）日：2003-01-16

  A compound of the following formula (I): wherein R?1, R2, R3 and R4¿ are each independently hydrogen or a suitable substituent, in which R?1 and R2¿ together or R?2 and R3¿ together may form -(CH¿2?)n- (wherein n is an integer of 1 to 12) which is optionally interrupted by heteroatom(s) and optionally having suitable substituent(s); andW is , or ,or a salt thereof.The compound of the above formula (I) and a salt thereof are adenosine antagonists and are useful as medicaments.