N-(9-ethylcarbazol-3-yl)-2-(2-phenylethylamino)acetamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: N-(9-ethylcarbazol-3-yl)-2-(2-phenylethylamino)acetamide
• 化学式: C₂₄H₂₅N₃O
• 分子量: 371.5
• InChiKey: AOSDATIPKDHZNO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  46.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• EP1499277A4
  申请人：——

  公开号：EP1499277A4

  公开（公告）日：2005-08-31
• MODIFICATION OF FEEDING BEHAVIOR
  申请人：Imperial College Innovations Limited

  公开号：EP1499277A2

  公开（公告）日：2005-01-26
• ASSESSMENT OF NEURONS IN THE ARCUATE NUCLEUS TO SCREEN FOR AGENTS THAT MODIFY FEEDING BEHAVIOR
  申请人：Oregon Health and Science University

  公开号：EP1585956A2

  公开（公告）日：2005-10-19
• [EN] MODIFICATION OF FEEDING BEHAVIOR<br/>[FR] MODIFICATION DE COMPORTEMENT ALIMENTAIRE
  申请人：IMP COLLEGE INNOVATIONS LTD

  公开号：WO2003026591A2

  公开（公告）日：2003-04-03

  Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering a therapeutically effective amount of PYY or an agonist thereof to the subject, thereby decreasing the calorie intake of the subject.
• [EN] ASSESSMENT OF NEURONS IN THE ARCUATE NUCLEUS TO SCREEN FOR AGENTS THAT MODIFY FEEDING BEHAVIOR<br/>[FR] EVALUATIONS DES NEURONES DANS LE NOYAU ARQUE POUR LE CRIBLAGE D'AGENTS DE MODIFICATION DU COMPORTEMENT ALIMENTAIRE
  申请人：UNIV OREGON HEALTH & SCIENCE

  公开号：WO2003027637A2

  公开（公告）日：2003-04-03

  Screening methods of use in identifying agents that affect caloric intake, food intake, appetite, and energy expenditure are disclosed herein. These methods are used to identify agents of use in treating obesity, or that can be used to decrease the weight of a subject. These methods can also be used to identify agents of use in treating anorexia or cachexia and can be used to increase appetite and to increase the weight and lean body mass of a subject.