4-[Ethyl-(3-methoxycarbonyl-1-methyl-butyl)-amino]-2-methyl-pentanoic acid methyl ester

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-[Ethyl-(3-methoxycarbonyl-1-methyl-butyl)-amino]-2-methyl-pentanoic acid methyl ester
• 英文别名: Methyl 4-[ethyl-(5-methoxy-4-methyl-5-oxopentan-2-yl)amino]-2-methylpentanoate
• 化学式: C₁₆H₃₁NO₄
• 分子量: 301.426
• InChiKey: FCAQPLUCQDBGJO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  21
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  55.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  三乙胺 、 甲基丙烯酸甲酯 以14%的产率得到
  参考文献：
  名称：

  Das Suresh, Kumar J. S. Dileep, Thomas K. George, Shivaramayya K., George+, J. Org. Chem, 59 (1994) N 3, S 628-634

  摘要：

  DOI：

文献信息

• Photocatalyzed multiple additions of amines to .alpha.,.beta.-unsaturated esters and nitriles
  作者：Suresh Das、J. S. Dileep Kumar、K. George Thomas、K. Shivaramayya、M. V. George

  DOI：10.1021/jo00082a021

  日期：1994.2

  Photoelectron-transfer-catalyzed intermolecular carbon-carbon bond formation of primary, secondary, and tertiary amines with alpha,beta-unsaturated esters and nitriles using photosensitizers such as anthraquinone, acridone, and dicyanoanthracene has been investigated. The addition of alpha-aminoalkyl radicals, generated via photoelectron-transfer processes, to olefinic substrates and the subsequent 1,5-hydrogen abstraction reactions of the amine-olefin adduct radicals lead to a number of interesting multiple-olefin-added products. The adducts of the primary and secondary amines with alpha beta-unsaturated esters undergo further cyclizations to give spiro and cyclic lactams, respectively.
• Das Suresh, Kumar J. S. Dileep, Thomas K. George, Shivaramayya K., George+, J. Org. Chem, 59 (1994) N 3, S 628-634
  作者：Das Suresh, Kumar J. S. Dileep, Thomas K. George, Shivaramayya K., George+

  DOI：——

  日期：——