(5E)-5-(5-hydroxyindol-3-ylidene)-3-(1H-indol-3-yl)pyrrol-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: (5E)-5-(5-hydroxyindol-3-ylidene)-3-(1H-indol-3-yl)pyrrol-2-one
• 化学式: C₂₀H₁₃N₃O₂
• 分子量: 327.3
• InChiKey: SDIQNSRIYWLPNK-MNDPQUGUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  25
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  77.5
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• SYSTEM AND METHOD OF INDUCIBLY CLUSTERING METABOLIC ENZYMES FOR THE PRODUCTION OF CHEMICALS USING CELL FACTORIES
  申请人：The Trustees of Princeton University

  公开号：US20210062165A1

  公开（公告）日：2021-03-04

  Provided herein is a system and method of optogenetically inducibly clustering metabolic enzymes for the production of chemicals using cell factories. More particularly, the described inducible protein clustering approach clusters metabolic enzymes by, e.g., a change in illumination conditions (either a switch from dark to light or from light to dark). Performing this clustering leads to an increase in the production of metabolites by the clustered enzymes. In some embodiments, a light-sensitive domain may be replaced with any inducible domain.