1,1-二乙氧基-1-苯基丙烷 | 10242-40-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1,1-二乙氧基-1-苯基丙烷
• 英文名称: 1,1-diethoxy-1-phenylpropane
• 英文别名: propiophenone diethylacetal；propiophenone-diethylacetal；Propiophenon-diaethylacetal；(1,1-diethoxy-propyl)-benzene；1,1-diethoxypropylbenzene
• CAS: 10242-40-7
• 化学式: C₁₃H₂₀O₂
• 分子量: 208.301
• InChiKey: ZNSMNHBLTQDASR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,1-二乙氧基-1-苯基丙烷 生成 达泊西汀杂质12
  参考文献：
  名称：

  Shiho, Nippon Kagaku Kaishi/Journal of the Chemical Society of Japan, 1947, vol. 68, p. 22

  摘要：

  DOI：
• 作为产物：
  描述：

  原甲酸三乙酯 、 苯丙酮 在 sodium methylate 作用下， 以 ethanol (EtOH) 、 乙醇 为溶剂， 以71%的产率得到1,1-二乙氧基-1-苯基丙烷
  参考文献：
  名称：

  Antibiotic Quinolones and derivatives

  摘要：

  公式I的化合物或其药用可接受的盐或水合物，其中X、Y、Z和R1至R7如本文所定义，是幽门螺杆菌的抑制剂，因此可用于治疗和预防消化性溃疡、胃炎、消化不良和胃癌。

  公开号：

  EP0811613A1

文献信息

• A convenient and practical method for the synthesis ofN-thiophosphoryl aldimines and ketimines
  作者：Xinyuan Xu、Chungui Wang、Zhenghong Zhou、Zebing Zeng、Xinpeng Ma、Guofeng Zhao、Chuchi Tang

  DOI：10.1002/hc.20412

  日期：2008.4

  A convenient and practical method for the preparation of N-thiophosphoryl imines was developed through the thermal condensation of acetals with different thiophosphoramides at 120–160°C. © 2008 Wiley Periodicals, Inc. Heteroatom Chem 19:238–244, 2008; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20412

  通过缩醛与不同硫代磷酰胺在 120-160°C 下的热缩合，开发了一种方便实用的制备 N-硫代磷酰亚胺的方法。© 2008 Wiley Periodicals, Inc. 杂原子化学 19:238–244, 2008; 在线发表于 Wiley InterScience (www.interscience.wiley.com)。DOI 10.1002/hc.20412
• Regioselective Addition of Alcohols to Internal 1-Aryl-1-alkynes Catalyzed by a Triangular Heterobimetallic Ir₂Pd Sulfido Cluster
  作者：Dai Masui、Youichi Ishii、Masanobu Hidai

  DOI：10.1246/cl.1998.717

  日期：1998.8

  The triangular heterobimetallic sulfido cluster[(Cp*Ir)2(μ3-S)2PdCl2] prepared from [PdCl2(cod)] and [Cp*IrCl(μ-SH)2IrCp*Cl] was found to catalyze the addition of alcohols to alkynes to give the corresponding ketals. In particular, internal 1-aryl-1-alkynes were transformed into the corresponding 2,2-dialkoxy-1-arylalkanes with high regioselectivity. The analogous Ir2PtS2 cluster proved to be much less selective.

  研究发现，由[PdCl2(cod)]和[Cp*IrCl(μ-SH)2IrCp*Cl]制备的三角形杂多金属硫化物簇[(Cp*Ir)2(μ3-S)2PdCl2]能催化醇与炔的加成反应，生成相应的酮。特别是，内部 1-芳基-1-炔以高区域选择性转化为相应的 2,2-二烷氧基-1-芳基烷。事实证明，类似的 Ir2PtS2 簇的选择性要低得多。
• Antibiotic quinolones and derivatives
  申请人：Pfizer Inc

  公开号：US06080757A1

  公开（公告）日：2000-06-27

  A compound of the formula I ##STR1## or a pharmaceutically acceptable salt or hydrate thereof, wherein X, Y, Z and R.sup.1 to R.sup.7 are as defined herein, are inhibitors of H. pylori and therefore of use in the treatment and prevention of peptic ulcers, gastritis, dyspepsia, and gastric cancer.

  该化合物的分子式为I ##STR1## 或其药用可接受的盐或水合物，其中X、Y、Z和R.sup.1到R.sup.7如本文所定义，是幽门螺杆菌的抑制剂，因此可用于治疗和预防消化性溃疡、胃炎、消化不良和胃癌。
• Balloon for medical tube and medical tube equipped with the same
  申请人：——

  公开号：US20010016727A1

  公开（公告）日：2001-08-23

  A cylindrical balloon for medical tubes, which is susceptible to bending operations, comprises a low stretchable section formed, by a partial cross-linking treatment, on the balloon along the circumferential direction thereof. A medical tube equipped with a balloon comprises a shaft tube for being inserted into a living body, a cylindrical balloon liquid-tightly connected to the shaft tube at the periphery on the tip thereof, a first lumen which is formed within the shaft tube and which communicates with the interior of the balloon, and at least one second lumen which is formed within the shaft tube and which is opened at the tip of the shaft tube; or comprises a shaft tube which is inserted into a living body, a cylindrical balloon, one end of which is liquid-tightly connected to the shaft tube at the tip thereof, a long tool for medical treatments or for diagnoses, whose tip portion is liquid-tightly connected to the other end of the balloon directly or indirectly, and a lumen which is formed within the shaft tube and communicates with the interior of the balloon so that a liquid can pass through the balloon and which accommodates the long tool for medical treatments or for diagnoses, wherein the cylindrical balloon is the same as that defined above.

  一种用于医疗管的圆柱形球囊，可进行弯曲操作，包括通过部分交联处理在球囊上沿其圆周方向形成的低伸展部分。装有球囊的医疗管包括一个用于插入活体的轴管、一个在其顶端外围与轴管液密连接的圆柱形球囊、一个在轴管内形成并与球囊内部相通的第一管腔，以及至少一个在轴管内形成并在轴管顶端开口的第二管腔；或包括一个插入活体内的轴管、一个圆柱形球囊（其一端在顶端与轴管液体紧固连接）、一个用于医疗或诊断的长工具（其顶端部分与球囊另一端直接或间接液体紧固连接），以及一个在轴管内形成并与球囊内部相通以便液体能通过球囊并容纳用于医疗或诊断的长工具的管腔，其中圆柱形球囊与上述定义的相同。
• Recording method for printing using two liquids on recording medium
  申请人：SEIKO EPSON CORPORATION

  公开号：US20030069329A1

  公开（公告）日：2003-04-10

  There is provided a recording method that can realize images which possess excellent fixation on recording media, excellent rubbing/scratch resistance and good quality. In the recording method, an ink composition comprising at least a colorant, resin emulsion particles, a water-soluble organic solvent, and water and a reaction solution containing a reactant capable of forming coagulate upon contact with the ink composition are deposited onto a recording medium to perform printing. This recording method comprises the steps of: depositing the reaction solution onto the recording medium; depositing the ink composition onto the recording medium to record an image; and washing the recording medium, on which the reaction solution and the ink composition have been deposited to perform printing, with a polar so olar solvent.

  本发明提供了一种记录方法，可实现在记录介质上具有出色的固定性、出色的耐摩擦/耐划伤性和良好质量的图像。在该记录方法中，将至少由着色剂、树脂乳液颗粒、水溶性有机溶剂和水组成的油墨组合物，以及含有与油墨组合物接触后能形成凝结物的反应物的反应溶液沉积到记录介质上进行印刷。这种记录方法包括以下步骤：将反应溶液沉积到记录介质上；将油墨组合物沉积到记录介质上以记录图像；以及用极性溶剂清洗沉积了反应溶液和油墨组合物以进行印刷的记录介质。