1,2,3,4-戊烷四羧酸 | 41892-62-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 1,2,3,4-戊烷四羧酸
• 英文名称: Pentan-tetracarbonsaeure-(1,2,3,4)
• 英文别名: 1-methyl-1,2,3,4-butane-tetracarboxylic acid；Pentane-1,2,3,4-tetracarboxylic acid
• CAS: 41892-62-0
• 化学式: C₉H₁₂O₈
• 分子量: 248.189
• InChiKey: HVNWRBWNOPYOER-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  149
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  3-methyltetrahydrophthalic anhydride 以78%的产率得到1,2,3,4-戊烷四羧酸
  参考文献：
  名称：

  Process for preparing polycarboxylic acid

  摘要：

  本发明公开了一种制备多羧酸的方法，该方法包括将马来酸酐和二烯和/或相应酸的Diels-Alder反应产物在存在钨酸、钼酸和其杂多酸中的至少一种催化剂的情况下，通过过氧化氢进行氧化裂解。

  公开号：

  US04833272A1

文献信息

• MULTI-ARM POLYMERIC PRODRUG CONJUGATES OF TAXANE-BASED COMPOUNDS
  申请人：Nektar Therapeutics

  公开号：US20160235705A1

  公开（公告）日：2016-08-18

  Among other aspects, provided herein are multi-arm polymeric prodrug conjugates of taxane-based compounds and/or fluorinated forms thereof. Methods of preparing such conjugates as well as methods of administering the conjugates are also provided. Upon administration to a patient, release of the taxane-based compound is achieved.

  在其他方面，本文提供了紫杉醇类化合物和/或其氟化形式的多臂聚合物前药共轭物。还提供了制备这种共轭物的方法以及给药的方法。在给患者施用后，紫杉醇类化合物被释放。
• NOVEL TETRACARBOXYLIC DIANHYDRIDE, POLYIMIDE RESIN AND METHOD FOR PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITIONS, PATTERNING PROCESS, METHOD FOR FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC PARTS
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：US20190169211A1

  公开（公告）日：2019-06-06

  The present invention has been made in view of the circumstances herein. An object of the present invention is to provide: a tetracarboxylic dianhydride which can lead to a polyimide usable as a base resin of a photosensitive resin composition capable of forming a fine pattern and obtaining high resolution without impairing excellent characteristics such as mechanical strength and adhesiveness; a polyimide resin obtained by using the tetracarboxylic dianhydride; and a method for producing the polyimide resin. The tetracarboxylic dianhydride is shown by the following general formula (1).

  本发明是基于本文中的情况而作出的。本发明的目的是提供：一种四羧酸二酐，可导致聚酰亚胺，作为感光树脂组合物的基树脂，能够形成细微图案并获得高分辨率，同时不损害优异的特性，如机械强度和粘附性；通过使用该四羧酸二酐获得的聚酰亚胺树脂；以及生产该聚酰亚胺树脂的方法。该四羧酸二酐由以下通用式（1）所示。
• Production process for hydroxyalkyl (meth) acrylate
  申请人：Nippon Shokubai Co., Ltd.

  公开号：US20040030180A1

  公开（公告）日：2004-02-12

  There is disclosed a novel production process for a hydroxyalkyl (meth)acrylate in which: the diffusion of harmful substances due to disposal of catalysts can be reduced; and also the amount of the catalyst as used can be greatly saved in the entire production process. This production process comprises the step of carrying out a reaction between (meth)acrylic acid and an alkylene oxide in the presence of a catalyst in order to produce the hydroxyalkyl (meth)acrylate; with the production process being characterized by further comprising the step of recovering the catalyst as has been used for the reaction.

  揭示了一种新型的羟基烷基（甲基）丙烯酸酯的生产工艺，其中：可以减少由于催化剂废弃而导致有害物质的扩散；同时在整个生产过程中也可以大大节省所使用的催化剂量。该生产工艺包括在催化剂存在下进行丙烯酸和烷基氧化物之间的反应，以生产羟基烷基（甲基）丙烯酸酯；该生产工艺的特点是进一步包括回收已用于反应的催化剂的步骤。
• Method for preparing a ligand presenting assembly (LPA), an LPA and uses thereof
  申请人：Statens Serum Institut

  公开号：US20040086949A1

  公开（公告）日：2004-05-06

  The present invention relates to a method for preparing a ligand presenting assembly (LPA), an LPA, an immunological composition and a vaccine. The invention further relates to a method for generating antibodies, a kit for use in diagnosis and use of an LPA for preparing a pharmaceutical composition.

  本发明涉及一种制备配体呈现组装体（LPA）、LPA、免疫组合物和疫苗的方法。该发明还涉及一种产生抗体的方法，用于诊断的试剂盒以及使用LPA制备药物组合物的方法。
• NOVEL PEPTIDES DERIVED FROM NCAM (FGLs)
  申请人：Berezin Vladimir

  公开号：US20110098225A1

  公开（公告）日：2011-04-28

  The present invention relates to novel compounds comprising at most 13 contiguous amino acid residues derived from the fibronectin type 3,I1 module of neural cell adhesion molecule (NCAM), or a variant or fragment thereof, capable of interacting with an FGFR and thereby the compounds are capable of inducing differentiation, modulating proliferation, stimulate regeneration, neuronal plasticity and/or survival of cells. Further, the present invention relates to the use of said compounds for production of a medicament for treatment of conditions and diseases, wherein NCAM and/or FGFR play a prominent role.

  本发明涉及新颖化合物，包括最多13个连续氨基酸残基，这些残基来源于神经细胞粘附分子（NCAM）的纤维连接蛋白3,I1模块，或者其变体或片段，能够与FGFR相互作用，因此这些化合物能够诱导细胞分化，调节增殖，刺激再生，神经元可塑性和/或细胞存活。此外，本发明涉及上述化合物的用途，用于制备用于治疗条件和疾病的药物，其中NCAM和/或FGFR发挥重要作用。