戊二酸-尿素(1:1) | 21835-54-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 戊二酸-尿素(1:1)
• 英文名称: urea glutaric acid
• 英文别名: UGA；Einecs 244-607-0；pentanedioic acid;urea
• CAS: 21835-54-1
• 化学式: 2CH₄N₂O*C₅H₈O₄
• 分子量: 252.227
• InChiKey: FWNHWJYVALADEQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.65
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  144
• 氢给体数：
  4
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  戊二酸-尿素(1:1) 以 甲醇 为溶剂， 以of glutaric acid having a purity of 98.5% was obtained的产率得到戊二酸
  参考文献：
  名称：

  Method for obtaining glutaric acid, succinic acid, and adipic acid from

  摘要：

  从工业副产物中获取戊二酸、琥珀酸和己二酸的方法，该副产物包含戊二酸、琥珀酸和己二酸，包括以下步骤：(1)将含有1至2摩尔尿素的溶液与该酸混合物接触，以沉淀尿素-戊二酸加合物，使得当己二酸含量在0%至7%时，剩余在溶液中的戊二酸与琥珀酸的重量比为1.2或以下，当己二酸含量大于7%且小于等于30%时，重量比为1.4或以下；将沉淀的尿素-戊二酸加合物从溶液中分离出来；(2)向溶液中添加更多的尿素和/或浓缩步骤(1)中得到的溶液，以沉淀尿素-琥珀酸加合物；将沉淀的尿素-琥珀酸加合物从溶液中分离出来；(3)将分离出的尿素-二羧酸加合物分解成相应的二羧酸和尿素。使用这种方法，首次可以成功有效地将含有戊二酸、琥珀酸和己二酸的混合物分离成各自的组分。

  公开号：

  US04146730A1
• 作为产物：
  描述：

  戊二酸 、 尿素 以 水 为溶剂， 反应 720.0h， 生成 戊二酸-尿素(1:1)
  参考文献：
  名称：

  Synthesis and characterization analysis of unique organic crystal – Urea Glutaric acid, an optimistic candidate for optical device applications

  摘要：

  Urea Glutaric acid (UGA), an organic compound was grown and its diverse characterizations were studied. XRD results confirmed the structure as monoclinic with the space group of C2/c. FTIR results confirmed the basic functional groups present in crystal was noticed. The optical properties have been studied by absorbance measurements in the wave length region from 200 nm to 800 nm. NLO (third order) properties were studied by Z-Scan method declares UGA, a successful material in nonlinear optics. The fluorescence spectrum indicates an electronic excitation at 481 nm and its thermal studies was done to determine the stability of the grown material under decomposition. Laser damage threshold was calculated to predict its resistance for high power laser radiation. The hardness and dielectric properties of UGA was explained from Vicker's micro hardness and dielectric analysis. Hence, the results from various characterizations confirmed that UGA is an enticing aspirant over device fabrication in nonlinear optics.

  DOI：

  10.1016/j.physb.2019.411804

文献信息

• Drug composition and coating
  申请人：W. L. Gore & Associates, Inc.

  公开号：US10561766B2

  公开（公告）日：2020-02-18

  According to the invention there is provided inter alia a medical device for delivering a paclitaxel to a tissue, the device the device having a coating layer applied to a surface of the device, the coating layer comprising components i), ii) and iii), wherein component i) is a therapeutic agent which is paclitaxel; and component ii) is urea or a pharmaceutically acceptable salt thereof, or a urea derivative or a pharmaceutically acceptable salt thereof; and component iii) is succinic acid, glutaric acid or caffeine, or a pharmaceutically acceptable salt of any one thereof.

  根据本发明，特别提供了一种用于向组织输送紫杉醇的医疗设备，该设备的表面涂有涂层，涂层由 i)、ii)和 iii)组成，其中 成分 i) 是紫杉醇治疗剂；以及 成分 ii）是脲或其药学上可接受的盐，或脲衍生物或其药学上可接受的盐；以及 成分 iii）是琥珀酸、戊二酸或咖啡因，或其中任何一种的药学上可接受的盐。
• THERMAL DISSOLUTION CATALYSIS METHOD FOR PREPARING LIQUID FUEL FROM LIGNITE AND THE CATALYST AND THE SOLVENT SUITABLE FOR THE METHOD
  申请人：Wu Ke

  公开号：US20100258479A1

  公开（公告）日：2010-10-14

  The present invention relates to coal chemical processing, and particularly to a thermal dissolution catalysis method for preparing liquid fuel from lignite. The method comprises steps of: 1) crushing and drying lignite into coal powder; 2) stirring and mixing coal powder, a solvent and a catalyst sufficiently to form coal slurry, wherein there are 30-40% mass of coal powder, 60-70% mass of solvent, and 0.5-1% mass of catalyst relative to coal powder mass; 3) subjecting the coal slurry to thermal dissolution catalysis reaction to obtain thermal dissolution liquefied product, wherein the reaction is carried out for 30-60 minutes at a temperature 390-450° C. under a pressure 5.0-9.0 MPa; 4) separating the thermal dissolution liquefied product into gas, liquid and solid phases; and 5) upgrading the liquid product into liquid fuel. The present invention further discloses a catalyst and a solvent for use in the above method. The method according to the present invention requires moderate operation conditions and can enable organic matter in the lignite to convert at a relatively high level, the liquid fuel product, after being processed, can be used to prepare engine fuel meeting a national standard; the method requires a simple preparation apparatus, a small investment and a low cost and is a coal liquefying method meeting China's status quo.
• DRUG COMPOSITION AND COATING
  申请人：W. L. Gore & Associates, Inc.

  公开号：US20170072116A1

  公开（公告）日：2017-03-16

  According to the invention there is provided inter alia a medical device for delivering a paclitaxel to a tissue, the device the device having a coating layer applied to a surface of the device, the coating layer comprising components i), ii) and iii), wherein component i) is a therapeutic agent which is paclitaxel; and component ii) is urea or a pharmaceutically acceptable salt thereof, or a urea derivative or a pharmaceutically acceptable salt thereof; and component iii) is succinic acid, glutaric acid or caffeine, or a pharmaceutically acceptable salt of any one thereof.