1,2-环戊烷二羰基二氯化物 | 501666-10-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 中文名称: 1,2-环戊烷二羰基二氯化物
• 英文名称: Cyclopentane-1,2-dicarbonyl dichloride
• 英文别名: cyclopentane-1,2-dicarbonyl chloride
• CAS: 501666-10-0
• 化学式: C₇H₈Cl₂O₂
• 分子量: 195.045
• InChiKey: RWRQCVAIGFYBHR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,2-环戊烷二羰基二氯化物 以 二氯甲烷 、 丙酮 为溶剂， 反应 15.0h， 生成
  参考文献：
  名称：

  Gyermek, Laszlo; Lee, Chingmuh; Cho, Young-Moon, Medicinal Chemistry Research, 2002, vol. 11, # 2, p. 116 - 136

  摘要：

  DOI：

文献信息

• Dihydroxy compound mixtures and polymers thereof
  申请人：GENERAL ELECTRIC COMPANY

  公开号：EP0736561A2

  公开（公告）日：1996-10-09

  Dihydroxy compounds with outstanding thermal stability contain a specified amount of o,p-bisphenol and polymers of dihydroxy compounds having terminal groups derived from o,p-bisphenol and show outstanding retention stability during molding. A dihydroxy compound mixture is obtained by adding (A) o,p-bisphenol having a specified structure to (B) a dihydroxy compound having a purity of 99.95% by weight or above as measured by high-performance liquid chromatography using a unit equipped with an ultraviolet absorption detector in which the o,p-bisphenol (A) is contained in the amount of 5 x 10-5 to 3 x 10-2 moles with respect to a total of 1 mole of the dihydroxy compound. Polymers have units derived from dihydroxy compounds and terminal groups derived from (A) o,p-bisphenol.

  具有出色热稳定性的二羟基化合物含有一定量的邻，对二酚，以及二羟基化合物的聚合物，其末端基团来自邻，对二酚，并在成型过程中显示出出色的保持稳定性。 二羟基化合物混合物是将(A)具有特定结构的邻，对双酚加入到(B)二羟基化合物中得到的，二羟基化合物的纯度为 99.95%（重量）或以上，该纯度是通过配备紫外线吸收检测器的高效液相色谱法测量的，其中邻，对双酚(A)的含量为 5 x 10-5 至 3 x 10-2 摩尔，二羟基化合物的总量为 1 摩尔。 聚合物的单元来自二羟基化合物，末端基团来自（A）邻，对二酚。
• PROCESS FOR PRODUCING AROMATIC POLYCARBONATE
  申请人：TEIJIN LIMITED

  公开号：EP0982340A1

  公开（公告）日：2000-03-01

  An aromatic polycarbonate and an active-hydrogen compound are subjected to the transesterification reaction in the presence of a transesterification catalyst under a reduced pressure condition followed by reaction with a salicylic acid ester derivative expressed by the following chemical formula (1), wherein X is methyl or ethyl, and Y is a carbonyl group or a divalent functional group expressed by the following formula (2), (where Z is an alkylene group having a carbon number of 1 to 30, an arylene group having a carbon number of 6 to 30 or an aralkylene group having a carbon number of 7 to 30)}. An aromatic polycarbonate having a high molecular weight can be produced by this process.

  芳香族聚碳酸酯和活性氢化合物在减压条件下，在酯交换催化剂存在下进行酯交换反应，然后与下式(1)表示的水杨酸酯衍生物反应、 其中 X 是甲基或乙基，Y 是羰基或下式（2）表示的二价官能团、 (其中 Z 是碳原子数为 1 至 30 的亚烷基、碳原子数为 6 至 30 的芳烷基或碳原子数为 7 至 30 的芳烷基）}。 通过该工艺可生产出具有高分子量的芳香族聚碳酸酯。
• Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction
  申请人：Emory University

  公开号：US10632120B2

  公开（公告）日：2020-04-28

  The disclosure provides methods of use of certain compounds that are useful for treating certain symptoms of endocrine disturbances, and in particular those associated with hot flashes.

  本公开提供了某些化合物的使用方法，这些化合物可用于治疗内分泌紊乱的某些症状，尤其是与潮热相关的症状。
• US6300459B1
  申请人：——

  公开号：US6300459B1

  公开（公告）日：2001-10-09
• [EN] NOVEL HETEROCYCLIC AMINO CARBONYL DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS<br/>[FR] NOUVEAUX DERIVES D'AMINO CARBONYLE HETEROCYCLIQUE UTILES COMME INHIBITEURS DE LA SYNTHASE DE MONOXYDE D'AZOTE
  申请人：SEARLE & CO

  公开号：WO2000063195A1

  公开（公告）日：2000-10-26

  The current invention discloses novel heterocyclic amino carbonyl derivatives useful as nitric oxide synthase inhibitors