1,3-二[3-(二甲氨基)丙基]硫代脲 | 18884-15-6

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫脲类
• 中文名称: 1,3-二[3-(二甲氨基)丙基]硫代脲
• 英文名称: N¹,N³-bis(3-dimethylaminopropyl)-thiourea
• 英文别名: Urea, 1,3-bis(3-(dimethylamino)propyl)-2-thio-；1,3-bis[3-(dimethylamino)propyl]thiourea
• CAS: 18884-15-6
• 化学式: C₁₁H₂₆N₄S
• 分子量: 246.42
• InChiKey: YLMXNQPOOVZIHK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  16
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  62.6
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1,3-二[3-(二甲氨基)丙基]硫代脲 在 mercury(II) oxide 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以13.14 g的产率得到N¹,N³-bis(3-dimethylaminopropyl)-carbodiimide
  参考文献：
  名称：

  乙腈中杂烷基侧链胍的碱性

  摘要：

  使用紫外/可见分光光度法滴定法在乙腈 (MeCN) 中测定了七种新型胍衍生物的 pKa 值，其中六种具有能够形成分子内氢键的杂烷基取代基。获得的 pKa 值范围从 24.7 到 27.2。在研究的胍中，最基本的被发现是大约。比众所周知的超强碱 N1,N1,N3,N3-四甲基胍 (TMG) 碱性强 4 个 pKa 单位。将测得的 pKa 值变化趋势与实验（由扩展动力学方法确定）和理论 [B3LYP/6-311+G(2df,p)//B3LYP/6-31G(d)] 气体进行比较-相质子亲和力。结果表明，乙腈中带有二甲基氨基丙基取代基的碱的碱性排序遵循气相中遇到的趋势。然而，

  DOI：

  10.1002/ejoc.200800673
• 作为产物：
  描述：

  二硫化碳 、 N,N-二甲基-1,3-二氨基丙烷 以 乙醇 为溶剂， 反应 22.0h， 生成 1,3-二[3-(二甲氨基)丙基]硫代脲
  参考文献：
  名称：

  Synthesis and properties of novel guanidine bases. N,N′,N″-Tris(3-dimethylaminopropyl)-guanidine

  摘要：

  The synthesis of novel N,N',N''-tris(3-dimethylaminopropyl)-guanidine 1 is described and X-ray structure of its hexafluorophosphate salt measured (1H center dot PF6). The hydrogen bonding in protonated 1 and in 1H center dot PF6 is also discussed. (c) 2005 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetlet.2005.10.035

文献信息

• [EN] N, N', N''-TRIS-(3-DIMETHYLAMINOPROPYL)-GUANIDINE. THE PROCEDURE OF PREPARATION FROM CARBODIIMIDE AND APPLICATION IN REACTIONS OF TRANSESTERIFICATION OF OIL<br/>[FR] N, N', N''-TRIS-(3-DIMETHYLAMINOPROPYL)-GUANIDINE. PROCEDE DE PREPARATION ET APPLICATION DANS LA TRANSESTERIFICATION D'HUILES VEGETALES
  申请人：RUDER BOSKOVIC INST

  公开号：WO2005100306A1

  公开（公告）日：2005-10-27

  The present invention provides procedures for preparation of N, N', N''-tris-(3-dimethylaminopropyl)-guanidine by addition of 3-dimethylaminopropylamine to N1, N3-bis-(3-dimethylaminopropyl)-carbodiimide. The latter compound was prepared in two steps starting from commercially available 3-dimethylaminpropyl amine and carbon disulfide followed by desulfurization of the formed thiourea with yellow mercury(II)-oxide. The so obtained guanidine derivative was successfully applied as catalyst in the transesterification of sunflower, soybean and rapeseed oil.

  本发明提供了一种通过将3-二甲基氨基丙胺加入N1, N3-双(3-二甲基氨基丙基)-碳酰亚胺制备N, N', N''-三-(3-二甲基氨基丙基)-胍的方法。后一种化合物是通过从商业可获得的3-二甲基氨基丙胺和二硫化碳开始的两步法制备的，随后用二氧化汞(II)对生成的硫氨基脲进行脱硫。所得的胍衍生物成功地应用于向日葵、大豆和油菜籽油的酯交换反应中作为催化剂。
• METHOD FOR PRODUCING ARYL, HETEROARYL, OR ALKENYL-SUBSTITUTED UNSATURATED HYDROCARBON
  申请人：Nishizawa Toshiaki

  公开号：US20120142975A1

  公开（公告）日：2012-06-07

  The present invention relates to a method for producing aryl-, heteroaryl- or alkenyl-substituted unsaturated hydrocarbons, containing: reacting aryl halides, heteroaryl halides or alkenyl halides with alkynes or alkenes in the presence of a palladium catalyst to obtain a crude product, and subsequently distillatively purifying the crude product in the presence of a compound having at least one NC═S group.

  本发明涉及一种生产含芳基、杂芳基或烯基取代的不饱和烃的方法，包括：在钯催化剂存在下，将芳基卤化物、杂芳基卤化物或烯基卤化物与炔烃或烯烃反应，以获得粗产品，随后在至少含有一个NC═S基团的化合物存在下，对粗产品进行蒸馏纯化。
• BONDING METHOD, BONDABILITY IMPROVING AGENT, SURFACE MODIFICATION METHOD, SURFACE MODIFYING AGENT, AND NOVEL COMPOUND
  申请人：MORI Kunio

  公开号：US20160152641A1

  公开（公告）日：2016-06-02

  To provide a technique by which an —OH group can be effectively formed on a material surface for the purpose of making the material suitable for bonding (for example, for molecular bonding) that utilizes a chemical reaction (chemical binding). [Solution] A bonding method for bonding a substrate A and a substrate B, which comprises: a step for applying an agent that contains the compound (α) described below on the surface of the substrate A; a step for arranging the substrate B so as to face the compound (α) that is present on the surface of the substrate A; and a step for integrally bonding the substrate A and the substrate B by applying a force onto the substrate A and/or the substrate B. The compound (α) is a compound that has an OH group or an OH-forming group, an azide group and a triazine ring in each molecule, and the substrate A is configured using a polymer.

  提供一种技术，通过该技术可以在材料表面有效形成一个—OH基团，以使材料适合于结合（例如，用于分子结合），利用化学反应（化学结合）。【解决方案】一种用于将基板A和基板B结合的结合方法，包括：在基板A表面涂覆含有下述化合物（α）的试剂的步骤；将基板B配置成与存在于基板A表面上的化合物（α）面对面的步骤；通过对基板A和/或基板B施加力将基板A和基板B整体结合的步骤。化合物（α）是一种在每个分子中具有一个—OH基团或—OH形成基团、一个叠氮基团和一个三嗪环的化合物，基板A是由聚合物构成的。
• ONIUM SALT AND COMPOSITION COMPRISING THE SAME
  申请人：ASAHI KASEI E-MATERIALS CORPORATION

  公开号：US20160229801A1

  公开（公告）日：2016-08-11

  The onium salt of the present invention contains predetermined compound A represented by the general formula (1). The composition of the present invention contains the onium salt of the present invention, and an onium salt containing predetermined compound B represented by the general formula (2). The onium salt and the composition of the present invention exert well-balanced excellent physical properties in terms of cold curing properties, storage stability, thermal shock resistance after curing, and moisture resistance.

  本发明的季铵盐包含由通式（1）表示的预定化合物A。本发明的组合物包含本发明的季铵盐，以及由通式（2）表示的含有预定化合物B的季铵盐。本发明的季铵盐和组合物在冷固化性能、储存稳定性、固化后的耐热冲击性和耐湿性方面表现出良好的平衡优异物理性能。
• POLYMER SHEET FOR INNER LINER, POLYMER LAMINATE FOR INNER LINER, AND PNEUMATIC TIRE
  申请人：SUGIMOTO Mutsuki

  公开号：US20120024447A1

  公开（公告）日：2012-02-02

  A pneumatic tire is provided which includes a polymer sheet for an inner liner composed of a polymer composition including: a polymer component containing more than or equal to 5% by mass and less than or equal to 40% by mass of a styrene-isobutylene-styrene triblock copolymer and more than or equal to 60% by mass and less than or equal to 95% by mass of a rubber component of at least one kind selected from the group consisting of natural rubber, isoprene rubber, and butyl rubber; and more than or equal to 0.1 part by mass and less than or equal to 5 parts by mass of sulfur with respect to 100 parts by mass of the polymer component. The pneumatic tire has sufficient tackiness before vulcanization and vulcanization adhesiveness between the inner liner and a member adjacent thereto, and exhibits excellent air permeation resistance.

  提供了一种气动轮胎，其包括用于内衬的聚合物片，其由聚合物组合物组成，包括：聚合物成分，其含有等于或大于5重量％且小于或等于40重量％的苯乙烯-异丁烯-苯乙烯三嵌段共聚物，以及等于或大于60重量％且小于或等于95重量％的至少一种从天然橡胶，异戊二烯橡胶和丁基橡胶中选择的橡胶成分；以及相对于聚合物成分的100重量部分，等于或大于0.1重量部分且小于或等于5重量部分的硫。该气动轮胎在硫化之前具有足够的粘性和内衬与相邻部件之间的硫化粘附性，并表现出优异的防气渗透性。