1-(3-氨基苯基)-4,5-二氢-4-[[4-[[[5-羟基-6-(苯偶氮基)-7-磺酸根-2-萘基]氨基]羰基]苯基]偶氮]-5-羰基-1H-吡唑-3-羧酸二钠 | 5691-98-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 1-(3-氨基苯基)-4,5-二氢-4-[[4-[[[5-羟基-6-(苯偶氮基)-7-磺酸根-2-萘基]氨基]羰基]苯基]偶氮]-5-羰基-1H-吡唑-3-羧酸二钠
• 中文别名: 2,4,6,8-四甲基二十八烷酸
• 英文名称: 2,4,6,8-Tetramethyloctacosanoic acid
• CAS: 5691-98-5
• 化学式: C₃₂H₆₄O₂
• 分子量: 480.8
• InChiKey: QFTGBKLLECAONU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.9
• 重原子数：
  34
• 可旋转键数：
  26
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.97
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Extracts of Curcuma and Methods of Use Thereof
  申请人：Alberte Randall S.

  公开号：US20100098788A1

  公开（公告）日：2010-04-22

  The present invention relates in part to turmeric extracts that are useful for treating or preventing neurodegenerative disorders. Another aspect of the invention relates in part to turmeric extracts that are useful for treating or preventing inflammatory disorders. In some embodiments, the extracts comprise at least one compound selected from the group consisting of 25 to 500 μg bamosamine, 25 to 750 μg echinaxanthol, 100 to 3,000 μg bisdemethoxycurcumin, 50 to 500 μg daphniyunnine E and 500 to 75,000 μg curcumin per 100 mg of extract. Another aspect of the invention relates to pharmaceutical compositions comprising the aforementioned extracts. Another aspect of the invention relates to methods of treating or preventing neurodegenerative disorders comprising administering to a subject in need thereof an effective amount of the aforementioned extracts or compositions. Another aspect of the invention relates to methods of making the aforementioned extracts.
• COMPOSITIONS AND METHODS FOR THE DISRUPTION OF MYCOBACTERIUM BIOFILM
  申请人：Takayama Kuni

  公开号：US20130245116A1

  公开（公告）日：2013-09-19

  The present disclosure provides methods and compositions for the disruption of biofilms produced by Mycobacterium . Methods and compositions related to the prevention and treatment of Mycobacterium infections in which biofilm formation is implicated are also provided.