1-(4-(3-溴丙基)苯基)乙醇 | 134836-71-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1-(4-(3-溴丙基)苯基)乙醇
• 英文名称: 1-(4-(3-bromopropyl)phenyl)ethanol
• 英文别名: 1-[4-(3-bromopropyl)phenyl]ethanol
• CAS: 134836-71-8
• 化学式: C₁₁H₁₅BrO
• 分子量: 243.143
• InChiKey: YSJGBMHCQKSHLE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-(4-(3-溴丙基)苯基)乙醇 在 sodium azide 、 (二氯碘)-苯 作用下， 以 乙腈 为溶剂， 反应 10.0h， 以73%的产率得到1-[4-(3-溴丙基)苯基]乙酮
  参考文献：
  名称：

  直接由伯醇一锅法合成氨基甲酸酯叠氮化物和二氯碘代苯与叠氮化钠结合将仲醇氧化成酮

  摘要：

  已经开发了使用二氯化碘苯和叠氮化钠直接从伯醇直接有效合成氨基甲酰基叠氮化物的方法。此外，相同的试剂组合对于将仲醇氧化为相应的酮也是有效的。

  DOI：

  10.1002/adsc.200900428
• 作为产物：
  描述：

  1-[4-(3-溴丙基)苯基]乙酮 在 甲醇 、 sodium tetrahydroborate 作用下， 反应 2.0h， 以60%的产率得到1-(4-(3-溴丙基)苯基)乙醇
  参考文献：
  名称：

  Self-Limiting Robust Surface-Grafted Organic Nanofilms

  摘要：

  Robust surface-bound insulating polymer films with controlled thickness in <5 nm range are important for technological advances in diverse disciplines such as electrochemical sensors, molecular electronics, separations, and anticorrosive coatings. Creating these films by simple methods from readily available materials has been a significant challenge. Here we report a newly synthesized molecule combining styrene and thiol moieties, joined via a short linker, that binds to the gold surface, polymerizes, and cross-links polymer chains to form robust films with uniform and controlled thickness and complete surface coverage. Additional layers can be deposited. These films that bridge two- and three-dimensional materials show excellent stability and insulating properties.

  DOI：

  10.1021/cm903024h

文献信息

• One-Pot Synthesis of Carbamoyl Azides Directly from Primary Alcohols and Oxidation of Secondary Alcohols to Ketones Using Iodobenzene Dichloride in Combination with Sodium Azide
  作者：Xiao-Qiang Li、Wei-Kun Wang、Chi Zhang

  DOI：10.1002/adsc.200900428

  日期：2009.10

  An effective synthesis of carbamoyl azides directly from primary alcohols using iodobenzene dichloride in combination with sodium azide has been developed. Moreover, the same regent combination was also efficient for the oxidation of secondary alcohols to the corresponding ketones.

  已经开发了使用二氯化碘苯和叠氮化钠直接从伯醇直接有效合成氨基甲酰基叠氮化物的方法。此外，相同的试剂组合对于将仲醇氧化为相应的酮也是有效的。
• Nanothin polymer coatings containing thiol and methods of use thereof
  申请人：The University of Memphis Research Foundation

  公开号：US07829155B1

  公开（公告）日：2010-11-09

  The present invention provides a new monomer and methods of using the monomer to fabricate robust polymer surface coatings with controlled thicknesses between 1 and 5 nanometers. The coatings are composed of a new material containing polymerized monomers of 4-vinylbenzenepropanethiol. The polymer surface coating may be applied to metal and silicon. The method includes exposing a metal substrate to a solution of the monomer in hexanes in order to deposit a monolayer of the monomer onto the metal surface. The substrate is then irradiated with ultraviolet radiation in order to graft a thin polymer coating onto the surface. The procedure can be repeated in order to control the thickness of the coating between about 1 nm and 5 nm. Alternatively, thermally initiated polymerization or deposition of partially oligomerized monomers onto the surface provides nanothin coatings with identical performance. The coating provides complete surface coverage, is extremely robust, and exhibits excellent insulating and anti-corrosive properties.

  本发明提供了一种新的单体及其使用方法，用于制备厚度在1到5纳米之间的坚固聚合物表面涂层。这些涂层由含有4-乙烯基苯基丙硫醇聚合单体的新材料组成。聚合物表面涂层可应用于金属和硅。该方法包括将金属基底暴露于己烷中的单体溶液中，以便在金属表面上沉积单体的单分子层。然后，用紫外线辐射以便将薄聚合物涂层嫁接到表面上。该过程可以重复以控制涂层的厚度在约1 nm到5 nm之间。或者，通过热引发的聚合或部分寡聚单体沉积在表面上，提供具有相同性能的纳米薄涂层。该涂层提供完全的表面覆盖，极其坚固，并具有优异的绝缘和防腐性能。
• US7829155B1
  申请人：——

  公开号：US7829155B1

  公开（公告）日：2010-11-09
• One-Pot Synthesis of Symmetrical 1,3-Diarylureas or Substituted Benzamides Directly from Benzylic Primary Alcohols and Effective Oxidation of Secondary Alcohols to Ketones Using Phenyliodine Diacetate in Combination with Sodium Azide
  作者：Xiao-Qiang Li、Wei-Kun Wang、Yi-Xin Han、Chi Zhang

  DOI：10.1002/adsc.201000318

  日期：2010.10.4

  primary alcohols can be directly converted into symmetrical 1,3-diarylureas or substituted benzamides via an one-pot oxidative reaction using the combined reagent of phenyliodine diacetate and sodium azide. This new reaction constitutes a step-economical way to prepare symmetric 1,3-diarylureas or substituted benzamides depending upon the substituents on the phenyl rings of starting alcohols. The sodium

  使用二乙酸苯基碘和叠氮化钠的混合试剂，通过一锅氧化反应，可以将苄基伯醇直接转化为对称的1,3-二芳基脲或取代的苯甲酰胺。该新反应构成了一种经济的步骤，该方法可根据起始醇的苯环上的取代基制备对称的1,3-二芳基脲或取代的苯甲酰胺。原位生成的乙酸钠苯基碘碘二乙酸酯和叠氮化钠之间的配体交换过程中起着重要作用，在1,3-二芳基脲的形成中起着关键作用。另外，还发现，使用相同的苯碘二乙酸二苯酯和叠氮化钠的试剂体系，各种仲醇可以容易地以优异的产率被氧化成它们相应的酮。通常，在伯醇与有限量的苯乙酸二乙酸苯酯和叠氮化钠存在的伯醇存在下，仲醇优先被氧化成相应的酮。
• Self-Limiting Robust Surface-Grafted Organic Nanofilms
  作者：L. Todd Banner、Samuel Tekobo、Fernando Garay、Benjamin T. Clayton、Zachary P. Thomas、Ernö Lindner、Andrew G. Richter、Eugene Pinkhassik

  DOI：10.1021/cm903024h

  日期：2010.4.13

  Robust surface-bound insulating polymer films with controlled thickness in <5 nm range are important for technological advances in diverse disciplines such as electrochemical sensors, molecular electronics, separations, and anticorrosive coatings. Creating these films by simple methods from readily available materials has been a significant challenge. Here we report a newly synthesized molecule combining styrene and thiol moieties, joined via a short linker, that binds to the gold surface, polymerizes, and cross-links polymer chains to form robust films with uniform and controlled thickness and complete surface coverage. Additional layers can be deposited. These films that bridge two- and three-dimensional materials show excellent stability and insulating properties.