1-Boc-6-甲基-3-甲酰基吲哚 | 914348-95-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 中文名称: 1-Boc-6-甲基-3-甲酰基吲哚
• 英文名称: 1-Boc-6-Methyl-3-formylindole
• 英文别名: tert-butyl 3-formyl-6-methylindole-1-carboxylate
• CAS: 914348-95-1
• 化学式: C₁₅H₁₇NO₃
• 分子量: 259.3
• InChiKey: OMUFPIBMLHSVAQ-UHFFFAOYSA-N

物化性质

• 沸点：
  396.1±34.0 °C(Predicted)
• 密度：
  1.12±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  48.3
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 海关编码：
  2933990090

文献信息

• Mono- or di-substituted indole derivatives as dengue viral replication inhibitors
  申请人：Janssen Pharmaceuticals, Inc.

  公开号：US20170298017A1

  公开（公告）日：2017-10-19

  The present invention concerns mono- or di-substituted indole derivatives (I) which are useful to prevent or treat dengue viral infections and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.
• US9944598B2
  申请人：——

  公开号：US9944598B2

  公开（公告）日：2018-04-17