1-[2-(3-甲氧基苯基)-1-环己烯基]-N,N-二甲基甲胺 | 73825-64-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 1-[2-(3-甲氧基苯基)-1-环己烯基]-N,N-二甲基甲胺
• 英文名称: 1-(3-methoxyphenyl)-2-dimethyl-aminomethylcyclohex-1-ene
• 英文别名: 1,2-Dehydro Tramadol；1-[2-(3-methoxyphenyl)cyclohexen-1-yl]-N,N-dimethylmethanamine
• CAS: 73825-64-6
• 化学式: C₁₆H₂₃NO
• 分子量: 245.365
• InChiKey: FBIKAGZLTPYSQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Process for the purification of (RR-SS)-2-dimethyl-aminomethyl-1-(3-methoxyphenyl)cyclohexanol and its salts
  申请人：Chemagis Ltd.

  公开号：EP0778262B1

  公开（公告）日：2001-01-24
• Tramadol Hydrochloride Solution
  申请人：Athena Bioscience, LLC

  公开号：US20210137835A1

  公开（公告）日：2021-05-13

  Disclosed herein is an analgesic solution for the treatment of pain comprising a pain-relieving effective amount of tramadol or a pharmaceutically acceptable salt thereof, a method of treating pain by administering said analgesic solution to a subject in need thereof, a kit that includes containers of the analgesic solution, and a dosing regimen for the analgesic solution.
• TRAMADOL HYDROCHLORIDE SOLUTION
  申请人：Athena Bioscience, LLC

  公开号：US20210299045A1

  公开（公告）日：2021-09-30

  Disclosed herein is an analgesic solution for the treatment of pain comprising a pain-relieving effective amount of tramadol or a pharmaceutically acceptable salt thereof, a method of treating pain by administering said analgesic solution to a subject in need thereof, a kit that includes containers of the analgesic solution, and a dosing regimen for the analgesic solution.
• US5672755A
  申请人：——

  公开号：US5672755A

  公开（公告）日：1997-09-30