1-庚烷磺酰胺 | 57603-96-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 中文名称: 1-庚烷磺酰胺
• 英文名称: heptane-1-sulfonamide
• 英文别名: Heptan-sulfonsaeure-(1)-amid；Heptylsulfonsaeure-amid；Heptan-1-sulfonamid；1-Heptanesulfonamide
• CAS: 57603-96-0
• 化学式: C₇H₁₇NO₂S
• 分子量: 179.283
• InChiKey: XXRLNWSPPBSGMY-UHFFFAOYSA-N

物化性质

• 沸点：
  287.9±23.0 °C(Predicted)
• 密度：
  1.062±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  68.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-庚烷磺酰胺 、 异氰酸正丁酯 在 三乙胺 作用下， 生成 N-butyl-N'-(heptane-1-sulfonyl)-urea
  参考文献：
  名称：

  Hoekfelt,B.; Joensson,A., Journal of medicinal and pharmaceutical chemistry, 1962, vol. 5, p. 231 - 239

  摘要：

  DOI：
• 作为产物：
  描述：

  1-庚烷磺酰氯 在 氨 作用下， 生成 1-庚烷磺酰胺
  参考文献：
  名称：

  Johnson; Sprague, Journal of the American Chemical Society, 1936, vol. 58, p. 1351

  摘要：

  DOI：

文献信息

• AZO COMPOUND, INK CONTAINING AZO COMPOUND, AND DISPLAY AND ELECTRONIC PAPER CONTAINING THE INK
  申请人：MITSUBISHI CHEMICAL CORPORATION

  公开号：US20150191601A1

  公开（公告）日：2015-07-09

  An azo compound excellent in solubility in solvent and having a high absorbance coefficient is disclosed, as well as an ink containing the azo compound. Such an ink contains a solvent having a relative permittivity at 22° C. and at a measurement frequency of 1 kHz of 3 or less and having a solubility in water at 25° C. of 20 mg/L or less, and an azo compound.

  本发明公开了一种在溶剂中溶解性优良且具有较高吸光系数的偶氮化合物，以及含有该偶氮化合物的墨水。这种墨水包含一种在22°C时相对介电常数为3或以下且在1 kHz测量频率下的溶剂，其在25°C时在水中的溶解度为20毫克/升或更低，以及一种偶氮化合物。
• AMIDINOANILINE DERIVATIVE
  申请人：AJINOMOTO CO., INC.

  公开号：US20130023563A1

  公开（公告）日：2013-01-24

  Provided are a novel amidine derivative having an activated blood coagulation factor X inhibitory activity, a production method thereof, a production intermediate therefor, and a pharmaceutical composition containing the amidine derivative. An amidinoaniline derivative represented by the following formula (1-1) or a pharmaceutically acceptable salt thereof: , and a pharmaceutical composition containing the amidinoaniline derivative or a pharmaceutically acceptable salt thereof.

  提供了一种具有活化血凝血因子X抑制活性的新型胍衍生物，其制备方法，制备中间体以及含有该胍衍生物的药物组合物。所述胍胺苯衍生物如下式（1-1）所代表或其药用可接受的盐：<在式（1-1）中，每个符号如描述中定义>，以及含有该胍胺苯衍生物或其药用可接受的盐的药物组合物。
• OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST
  申请人：Shibasaki Masakatsu

  公开号：US20100298559A1

  公开（公告）日：2010-11-25

  There is provided a novel optically active dinickel complex and/or a production method of an optically active amine by an asymmetric Mannich reaction using the dinickel complex as a catalyst. An optically active dinickel complex of Formula (I) or Formula (I′): [where R 0 , R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , and R 7 are each independently a hydrogen atom, a halogen atom, a C 1-10 alkyl group or a C 1-10 alkoxy group, etc., R 2 and R 3 together form, together with a benzene ring bonded to them, a naphthalene ring, etc. A novel production method of an optically active amine by an asymmetric Mannich reaction using the dinickel complex as a catalyst.

  提供了一种新型光学活性二镍配合物和/或使用该二镍配合物作为催化剂进行不对称Mannich反应制备光学活性胺的生产方法。公式（I）或公式（I′）的光学活性二镍配合物：[其中R0、R1、R2、R3、R4、R5、R6和R7分别独立地是氢原子、卤素原子、C1-10烷基或C1-10烷氧基等，R2和R3连同与它们结合的苯环形成萘环等。使用该二镍配合物作为催化剂，通过不对称Mannich反应制备光学活性胺的新型生产方法。
• STILBENE-BASED COMPOUND OR SALT THEREOF, AND POLARIZING FILM, POLARIZING PLATE, AND DISPLAY DEVICE
  申请人：NIPPON KAYAKU KABUSHIKI KAISHA

  公开号：US20200157353A1

  公开（公告）日：2020-05-21

  The present disclosure is a stilbene-based compound or a salt thereof represented by a following formula (1), wherein a group X represents a nitro group or an amino group optionally having a substituent; a group Y represents an amide group optionally having a substituent or a naphthotriazole group optionally having a substituent; and p and q each independently represent an integer of 0 to 2.

  本公开涉及一种基于stilbene的化合物或其盐，其表示如下式（1），其中X代表一个硝基或一个氨基，可选地具有取代基；Y代表一个酰胺基，可选地具有取代基，或一个萘三唑基，可选地具有取代基；p和q各自独立地代表0到2的整数。
• Sulfonic acids, their derivatives and pharmaceutical compositions containing them
  申请人：Dompé S.P.A.

  公开号：EP1457485A1

  公开（公告）日：2004-09-15

  Selected sulfonic acids, their derivatives and pharmaceutical compositions containing such compounds are useful in inhibiting the chemotactic activation of neutrophils (PMN leukocytes) induced by the interaction of Interleukin-8 (IL-8) with CXCR1 and CXCR2 membrane receptors. The compounds are used for the prevention and treatment of pathologies deriving from said activation. Notably, the selected sulfonic acids and their derivativas are devoid of cyclo-oxygenase inhibition activity and are particularly useful in the treatment of neutrofil-dependent pathologies such as psoriasis, ulcerative colitis, melanoma, chronic obstructive pulmonary disease (COPD), bullous pemphigoid, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and in the prevention and treatment of damages caused by ischemia and reperfusion.

  选择性磺酸、它们的衍生物和含有这些化合物的药物组合物在抑制由白细胞介素-8（IL-8）与CXCR1和CXCR2膜受体相互作用引起的中性粒细胞（PMN白细胞）趋化活化方面是有用的。这些化合物用于预防和治疗由该活化引起的病理状况。值得注意的是，所选的磺酸及其衍生物不具有环氧化酶抑制活性，特别适用于治疗中性粒细胞依赖性病理状况，如银屑病、溃疡性结肠炎、黑色素瘤、慢性阻塞性肺疾病（COPD）、大疱性类天疱疮、类风湿性关节炎、特发性纤维化、肾小球肾炎以及预防和治疗缺血再灌注引起的损伤。