1-溴-5-氟-4-甲基-2-硝基苯 | 1345471-69-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1-溴-5-氟-4-甲基-2-硝基苯
• 中文别名: 2-氟-4-溴-5-硝基甲苯
• 英文名称: 1-bromo-5-fluoro-4-methyl-2-nitrobenzene
• CAS: 1345471-69-3
• 化学式: C₇H₅BrFNO₂
• 分子量: 234.025
• InChiKey: TVQLPBXVLOYFQS-UHFFFAOYSA-N

物化性质

• 沸点：
  253.6±35.0 °C(Predicted)
• 密度：
  1.696±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  45.8
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 海关编码：
  2904909090
• 危险性防范说明：
  P261,P280,P301+P312,P302+P352,P305+P351+P338
• 危险性描述：
  H302,H315,H319,H335
• 储存条件：
  室温

SDS

Material Safety Data Sheet

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Section 1. Identification of the substance
Product Name: 1-Bromo-5-fluoro-4-methyl-2-nitrobenzene
Synonyms: 4-Bromo-2-fluoro-5-nitrotoluene

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Section 2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

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Section 3. Composition/information on ingredients.
Ingredient name: 1-Bromo-5-fluoro-4-methyl-2-nitrobenzene
CAS number: 1345471-69-3

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Section 4. First aid measures
Skin contact: Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact: Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation: Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion: Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

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Section 5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

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Section 6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution: Wear approved mask/respirator
Hand precaution: Wear suitable gloves/gauntlets
Skin protection: Wear suitable protective clothing
Eye protection: Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

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Section 7. Handling and storage
Handling: This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels.
Storage:

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Section 8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

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Section 9. Physical and chemical properties
Appearance: Not specified
Boiling point: No data
No data
Melting point:
Flash point: No data
Density: No data
Molecular formula: C7H5BrFNO2
Molecular weight: 234.0

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Section 10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen fluoride, hydrogen bromide.

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Section 11. Toxicological information
No data.

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Section 12. Ecological information
No data.

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Section 13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

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Section 14. Transportation information
Non-harzardous for air and ground transportation.

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Section 15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  1-溴-5-氟-4-甲基-2-硝基苯 在 盐酸 、 bis-triphenylphosphine-palladium(II) chloride 、 铁粉 、 sodium carbonate 、 potassium carbonate 作用下， 以 1,4-二氧六环 、 甲醇 、 水 、 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 反应 23.5h， 生成 N'-[2-cyclopropyl-4-(2-fluorophenoxy)-5-methylphenyl]-N-ethyl-N-methylmethanimidamide
  参考文献：
  名称：

  [EN] PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES
  [FR] PHÉNOXYPHÉNYLAMIDINES ET LEUR UTILISATION EN TANT QUE FONGICIDES

  摘要：

  公开号：

  WO2018108992A3

文献信息

• [EN] HALOGEN-SUBSTITUTED PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES<br/>[FR] PHÉNOXYPHÉNYLAMIDINES À SUBSTITUTION HALOGÈNE ET UTILISATION DE CELLES-CI EN TANT QUE FONGICIDES
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2016202742A1

  公开（公告）日：2016-12-22

  The present invention relates to halogen-substituted phenoxyphenylamidines of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and also to an agrochemical formulation for this purpose, comprising the halogen-substituted phenoxyphenylamidines according to the invention. Furthermore, the invention relates to a method for controlling unwanted microorganisms by applying the compounds according to the invention to the microorganisms and/or their habitat.

  本发明涉及一般式（I）的卤代苯氧基苯基酰胺衍生物，其制备方法，根据本发明用于控制不受欢迎的微生物的酰胺化合物的使用，以及用于此目的的农药配方，包括根据本发明的卤代苯氧基苯基酰胺衍生物。此外，该发明涉及通过将根据本发明的化合物应用于微生物和/或其栖息地来控制不受欢迎的微生物的方法。
• Regioselective Process for Preparing Benzimidazole Thiophenes
  申请人：Hornberger Keith

  公开号：US20080249301A1

  公开（公告）日：2008-10-09

  The present invention provides a process for preparing benzimidazole thiophene compounds of formula (I). Intermediates used in the process are also claimed.

  本发明提供了一种制备式(I)的苯并咪唑噻吩化合物的方法。该方法使用的中间体也被要求。
• [EN] PHENOXYHALOGENPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES<br/>[FR] PHÉNOXYHALOGÉNOPHÉNYLAMIDINES ET LEUR UTILISATION COMME FONGICIDES
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2017005710A1

  公开（公告）日：2017-01-12

  The present invention relates phenoxyhalogenphenylamidmes of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and also to an agrochemical formulation for this purpose, comprising the phenoxyhalogenphenylamidmes according to the invention. Furthermore, the invention relates to a method for controlling unwanted microorganisms by applying the compounds according to the invention to the microorganisms and/or their habitat.

  本发明涉及通式（I）的苯氧卤代苯基脲类化合物，其制备方法，以及根据本发明使用该脲类化合物来控制不良微生物的方法，以及用于此目的的农药配方，包括本发明的苯氧卤代苯基脲类化合物。此外，本发明还涉及通过将本发明的化合物应用于微生物和/或其栖息地来控制不良微生物的方法。
• [EN] ACTIVE COMPOUND COMBINATIONS<br/>[FR] COMBINAISONS DE COMPOSÉS ACTIFS
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2018108977A1

  公开（公告）日：2018-06-21

  The invention relates to active compound combinations, in particular within a composition, which comprises (A) one or more phenylamidine compounds of formula (I) and one or more fungicidal compounds (B). Moreover, the invention relates to a method for controlling the phytopathogenic fungi of plants, to the use of an active compound combination according to the invention for the treatment of one or more seeds, to a method for protecting one or more seeds and to the corresponding treated seed.

  本发明涉及活性化合物组合物，特别是包含（A）一种或多种公式（I）的苯胺化合物和一种或多种杀真菌化合物（B）的组合物，以及一种控制植物病原真菌的方法，使用本发明的活性化合物组合物治疗一种或多种种子的用途，一种保护一种或多种种子的方法以及相应的处理过的种子。
• ACTIVE COMPOUND COMBINATIONS
  申请人：Bayer CropScience Aktiengesellschaft

  公开号：EP3335559A1

  公开（公告）日：2018-06-20

  The invention relates to active compound combinations, in particular within a composition, which comprises (A) one or more phenylamidine compounds of formula (I) and one or more fungicidal compounds (B). Moreover, the invention relates to a method for controlling the phytopathogenic fungi of plants, to the use of an active compound combination according to the invention for the treatment of one or more seeds, to a method for protecting one or more seeds and to the corresponding treated seed.

  本发明涉及活性化合物组合，特别是一种组合物，它包括(A)一种或多种式(I)的苯基脒化合物和一种或多种杀真菌化合物(B)。此外，本发明还涉及一种控制植物病原真菌的方法，涉及根据本发明的活性化合物组合用于处理一种或多种种子的用途，涉及保护一种或多种种子的方法以及相应处理过的种子。