12,13-二羟基十八烷酸 | 585-20-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 12,13-二羟基十八烷酸
• 英文名称: 12,13-dihydroxyoctadecanoic acid
• CAS: 585-20-6
• 化学式: C₁₈H₃₆O₄
• 分子量: 316.481
• InChiKey: PEUSBAXOWSDDBR-UHFFFAOYSA-N

物化性质

• 沸点：
  484.2±15.0 °C(Predicted)
• 密度：
  1.001±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  22
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  77.8
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  顺式十二烷酸 在 甲酸 、 双氧水 作用下， 反应 2.0h， 生成 12,13-二羟基十八烷酸
  参考文献：
  名称：

  144.长链酸的合成。第三部分 炔酸的合成

  摘要：

  DOI：

  10.1039/jr9630000775

文献信息

• Bis-Platinum Complexes With Antitumor Activity
  申请人：Bernareggi Alberto

  公开号：US20100292322A1

  公开（公告）日：2010-11-18

  A compound of general formula (I): in which: R is selected from the group consisting of (C 1 -C 25 )alkyl, (C 2 -C 25 )alkenyl, aryl, (C 7 -C 10 )aralkyl; n and m are each independently an integer of two to eight; p is one or two; A is selected from the group consisting of —B—, —B—(CH 2 ) r —B—, —B—(CH 2 ) r —B—(CH 2 ) z —B—, wherein r and z are an integer from 2 to 8 , B is a —NR 1 — or —N(R 2 ) 2 + 1 /pQ −p group, in which R1 is selected from hydrogen, (C 1 -C 4 )alkyl, (C 1 -C 4 )acyl, tert-butoxycarbonyl, and R 2 is selected from hydrogen and (C 1 -C 4 )alkyl; Q −p is an anion selected from chloride, bromide, iodide, nitrate, sulphate, hydrogen sulphate, perchlorate, R 3 COO − wherein R 3 has the same meanings as R, independently from one another and R 4 —O—SO 3 − wherein R 4 is (C 2 -C 14 )alkyl with the proviso that, when Q −p is selected from chloride, bromide, iodide, nitrate, sulphate, hydrogen sulphate, perchlorate, R is not (C 1 -C 4 )alkyl.

  一个通式（I）的化合物：其中：R选自（C1-C25）烷基，（C2-C25）烯烃，芳基，（C7-C10）芳基烷基的群组；n和m分别独立地为2到8的整数；p为1或2；A选自—B—，—B—（CH2）r—B—，—B—（CH2）r—B—（CH2）z—B—的群组，其中r和z为2到8的整数，B为—NR1—或—N(R2)2+1/pQ−p群，其中R1选自氢，（C1-C4）烷基，（C1-C4）酰基，叔丁氧羰基，R2选自氢和（C1-C4）烷基；Q−p选自氯化物，溴化物，碘化物，硝酸盐，硫酸盐，氢硫酸盐，高氯酸盐，R3COO−其中R3与R具有相同的含义，独立地为R4—O—SO3−其中R4为（C2-C14）烷基，但当Q−p选自氯化物，溴化物，碘化物，硝酸盐，硫酸盐，氢硫酸盐，高氯酸盐时，R不是（C1-C4）烷基。
• Refrigerator oil composition
  申请人：IDEMITSU KOSAN COMPANY LIMITED

  公开号：EP0802254A1

  公开（公告）日：1997-10-22

  Disclosed is a refrigerator oil composition comprising at least one base oil selected from mineral oils and synthetic oils, and at least one hydroxy-fatty acid derivative selected from (A) hydroxy-fatty acids or their condensates, (B) metal salts or amine salts of hydroxy-fatty acids or their condensates, and (C) esters of hydroxy-fatty acids. The composition has an excellent lubricating property, while specifically improving the lubricity between aluminium materials and steel materials. This is effective for preventing such materials from being seized and worn, and is suitable as a lubricating oil in refrigerators using hydrogen-containing Flon refrigerants, such as R134a, that do not cause environmental pollution.

  本发明公开了一种冷冻机油组合物，该组合物包含至少一种选自矿物油和合成油的基础油，以及至少一种选自 (A) 羟基脂肪酸或其缩合物、(B) 羟基脂肪酸或其缩合物的金属盐或胺盐，以及 (C) 羟基脂肪酸酯的羟基脂肪酸衍生物。该组合物具有极佳的润滑性能，尤其能改善铝材料和钢材料之间的润滑性。这可有效防止此类材料卡死和磨损，适用于使用不会造成环境污染的含氢氟隆制冷剂（如 R134a）的冰箱的润滑油。
• BIS-PLATINUM COMPLEXES WITH ANTITUMOR ACTIVITY
  申请人：Sede Secondaria Della Cell Therapeutics, Inc.

  公开号：EP1968991A1

  公开（公告）日：2008-09-17
• TREATMENT OF RINGWORM
  申请人：Vernolix Limited

  公开号：EP2306997A1

  公开（公告）日：2011-04-13
• ADDITIVE COMPOSITIONS FOR DRILLING FLUIDS AND METHODS FOR THEIR USE
  申请人：The Lubrizol Corporation

  公开号：EP3283596A1

  公开（公告）日：2018-02-21