12-羟基硬脂酰胺 | 7059-49-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 12-羟基硬脂酰胺
• 英文名称: 12-Hydroxyoctadecanamide
• 英文别名: 12-hydroxyoctadecan-1-amide；12-Hydroxy-octadecansaeureamid；12-Hydroxystearamide
• CAS: 7059-49-6
• 化学式: C₁₈H₃₇NO₂
• 分子量: 299.497
• InChiKey: ALDZNWBBPCZXGH-UHFFFAOYSA-N

物化性质

• 沸点：
  459.9±18.0 °C(Predicted)
• 密度：
  0.923±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  21
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.944
• 拓扑面积：
  63.3
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  12-羟基硬脂酸 在 硫酸氢铵 、 disodium hydrogenphosphate 、 potassium dihydrogenphosphate 、 Bacillus cereus 、 iron(II) sulfate 、 calcium chloride 、 yeast extract 作用下， 反应 120.0h， 以24%的产率得到12-羟基硬脂酰胺
  参考文献：
  名称：

  蜡样芽胞杆菌50将12-羟基十八碳二烯酸生物转化为12-羟基十八碳二烯酰胺

  摘要：

  AbstractA new microbial isolate (Bacillus cereus 50) transformed 12‐hydroxyoctadecanoic acid to 12‐hydroxyoctadecanamide when grown aerobically in 1% yeast extract medium at 30°C, shaken at 250 rpm for 2 to 5 d. The compound was purified by thin‐layer chromatography and characterized by infrared, gas chromatography, mass spectrometry, and nuclear magnetic resonance. The yields of 12‐hydroxyoctadecanamide were 9.1 and 21.5% after 2 and 5 d, respectively.

  DOI：

  10.1007/s11746-997-0188-8

文献信息

• [EN] (R)-12-HYDROXYSTEARIC ACID HYDRAZIDES AS GELATORS AND SELF-STANDING GELS THEREOF<br/>[FR] HYDRAZIDES D'ACIDE (R)-12-HYDROXYSTÉARIQUE UTILISÉS COMME GÉLIFIANTS ET LEURS GELS AUTOPORTEURS
  申请人：UNIV GEORGETOWN

  公开号：WO2017117212A1

  公开（公告）日：2017-07-06

  (R)-12-hydroxystearic acid hydrazides as gelators and gels generated therefrom are provided. A series of (R)-12-hydroxystearic acid hydrazides produce gels that are self-standing and self-healing. The (R)-12-hydroxystearic acid hydrazides are capable of exhibiting gelling properties in a wide variety of solvents. The gels have demonstrated good potential for use in drug release.

  提供(R)-12-羟基硬脂酸腙作为凝胶剂及由此产生的凝胶。一系列(R)-12-羟基硬脂酸腙产生的凝胶具有自立和自修复性质。这些(R)-12-羟基硬脂酸腙能够在各种溶剂中展现凝胶特性。这些凝胶已经展示出在药物释放中的潜力。
• [EN] LOW MOLECULAR WEIGHT GELATORS FOR CRUDE OIL, PETROLEUM PRODUCT OR CHEMICAL SPILL CONTAINMENT<br/>[FR] GÉLIFIANTS DE FAIBLE POIDS MOLÉCULAIRE POUR CONFINER LES DÉVERSEMENTS ACCIDENTELS DE PÉTROLE BRUT, DE PRODUITS PÉTROLIERS OU AGENTS CHIMIQUES
  申请人：UNIV GEORGETOWN

  公开号：WO2012047251A1

  公开（公告）日：2012-04-12

  Low molecular weight gelators, methods of making such gelators, organogels comprising such gelators and systems and methods of using such gelators for the containment and/or remediation of a release and/or spill of a crude oil, a petroleum product and/or a chemical is described. In exemplary systems and methods, gels and/or emulsions formed from the combination and/or contact of such gelators and at least one of a crude oil, a petroleum product and a chemical from a release and/or spill into the environment can be used to recover these oils or chemicals while allowing the gelators to be recovered and reused to clean up or contain additional crude oil, petroleum products or chemicals.

  低分子量凝胶剂，制备此类凝胶剂的方法，包含此类凝胶剂的有机凝胶以及使用此类凝胶剂进行原油、石油产品和/或化学品泄漏和/或溢出的控制和/或治理的系统和方法已被描述。在示例系统和方法中，从此类凝胶剂的组合和/或接触与原油、石油产品和化学品之一泄漏和/或溢出到环境中形成的凝胶和/或乳化物可以用于回收这些油或化学品，同时允许回收和重复使用凝胶剂来清理或控制额外的原油、石油产品或化学品。
• Dye and ink jet printing ink
  申请人：KONICA MINOLTA HOLDINGS, INC.

  公开号：US20040106782A1

  公开（公告）日：2004-06-03

  A dye is disclosed, which is represented by the following formula: 1 wherein Z is an atomic group necessary to form a 6-membered nitrogen containing aromatic ring; R 11 is a hydrogen bonding group; R 12 , R 13 and R 14 are independently a hydrogen atom or a substituent; n11 and n13 are each an integer of 1 to 4; n12 is an integer of 1 to 3. There is also disclosed an ink for ink jet printing which contains the foregoing dye.

  揭示了一种染料，其表示为以下公式：1其中Z是形成一个含氮6元环芳香环所必需的原子基团；R11是一个氢键结合基团；R12、R13和R14分别是氢原子或取代基；n11和n13各自是1至4的整数；n12是1至3的整数。还披露了一种喷墨打印墨水，其中包含上述染料。
• [EN] LINEAR AND CYCLIC SILOXANES AND COSMETIC COMPOSITIONS MADE THEREOF<br/>[FR] SILOXANES LINÉAIRES ET CYCLIQUES ET COMPOSITIONS COSMÉTIQUES PRÉPARÉES À PARTIR DE CES DERNIERS
  申请人：DOW CORNING TORAY CO LTD

  公开号：WO2011068250A1

  公开（公告）日：2011-06-09

  The present invention relates to a novel organopolysiloxane having a specified structure and a cosmetic containing the aforementioned organopolysiloxane. The novel organopolysiloxane according to the present invention is volatile, possesses stability at low temperature, provides superior glossiness, and has a superior property with respect to miscibility with a UV- ray absorber, and which is useful as a replacement of octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, or methyltrimethicone. The cosmetic according to the present invention can provide superior feeling to the touch during use and a superior outer appearance. Furthermore, a degree of freedom in blending various components such as UV-ray absorbers into the cosmetic according to the present invention is increased.

  本发明涉及一种具有特定结构的新型有机硅聚合物和含有上述有机硅聚合物的化妆品。根据本发明的新型有机硅聚合物具有挥发性，在低温下具有稳定性，提供出色的光泽度，并具有与紫外线吸收剂混溶的优越性能，可用作八甲基环四硅氧烷、十甲基环五硅氧烷或甲基三甲基硅氧烷的替代品。根据本发明的化妆品在使用时可以提供出色的触感和优越的外观。此外，根据本发明的化妆品可以增加混合各种成分，如紫外线吸收剂的自由度。
• [EN] PERSONAL CARE COMPOSITIONS COMPRISING FATTY ACID AMIDE DERIVATIVES<br/>[FR] COMPOSITIONS DE SOIN PERSONNEL COMPRENANT DES DÉRIVÉS D'AMIDES D'ACIDE GRAS
  申请人：UNILEVER PLC

  公开号：WO2018019463A1

  公开（公告）日：2018-02-01

  In one embodiment, the present invention provides a personal care composition, comprising: (i) a compound of Formula (1) at a concentration from 0.0001 wt % to 20 wt % of the composition; wherein R is selected from the group consisting of C15-C23 conjugated dienes, C15-C23 hydroxylated mono unsaturated alkenes, and C15-C23 hydroxylated alkanes; wherein R1 is selected from the group consisting of H, C1-C4 alkyl, - CH2OH, -CH2(CH3)-OH,-[CH2]4-NH2, -CH2-CO2H, -[CH2]2-CO2H, (I), (II) and (III); wherein R3 is -CO2H; -CH2CO2H; -CH2CH2CO2H;; and (ii) a cosmetically acceptable carrier.

  在一个实施例中，本发明提供一种个人护理组合物，包括：(i) 按照浓度为0.0001重量%至20重量%的组合物的公式(1)的化合物；其中R从C15-C23共轭二烯烃、C15-C23羟基单不饱和烯烃和C15-C23羟基烷烃组成的群体中选择；其中R1从H、C1-C4烷基、- CH2OH、-CH2(CH3)-OH、-[CH2]4-NH2、-CH2-CO2H、-[CH2]2-CO2H、(I)、(II)和(III)组成的群体中选择；其中R3为-CO2H；-CH2CO2H；-CH2CH2CO2H；；和(ii) 一种化妆品可接受的载体。