13,14-二氢-15-酮前列腺素a2 | 74872-89-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 13,14-二氢-15-酮前列腺素a2
• 英文名称: 15-Keto-13,14-dihydroprostaglandin A2
• 英文别名: (Z)-7-[(1R,5S)-2-oxo-5-(3-oxooctyl)cyclopent-3-en-1-yl]hept-5-enoic acid
• CAS: 74872-89-2
• 化学式: C₂₀H₃₀O₄
• 分子量: 334.4
• InChiKey: FMKLAIBZMCURLI-BFVRRIQPSA-N

物化性质

• 沸点：
  510.5±33.0 °C(Predicted)
• 密度：
  1.043±0.06 g/cm3(Predicted)
• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  24
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  71.4
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Detection and Quantitation Method for Proteomics of Post-Translational Modifications
  申请人：Sichuan University

  公开号：US20200033361A1

  公开（公告）日：2020-01-30

  The present disclosure relates to the technical field of comparative proteomics, in particular to a detection and quantitation method for proteomics of post-translational modifications. With this method, the protein samples to be studied and internal standards are labeled with isobaric tandem mass tags, and tandem mass spectrometry analysis is carried out for the labeled peptide mixture, wherein the internal standard is a peptide mixture rich in post-translational modifications to be detected. Through this method, the signal of peptides containing the post-translational modifications to be detected can be amplified under the situation that mass spectrometer sensitivity is unchanged, and enrichment of the post-translational modification peptides is not needed. The probability of detecting the peptides containing the post-translational modifications to be detected by mass spectrometer and being selected for subsequent MS/MS analysis is increased.