15-甲基十七烷酸 | 29709-08-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 15-甲基十七烷酸
• 英文名称: 15-methylheptadecanoic acid
• 英文别名: 15-Methyl-heptadecansaeure；DL-15-Methyl-heptadecansaeure
• CAS: 29709-08-8
• 化学式: C₁₈H₃₆O₂
• 分子量: 284.483
• InChiKey: MAFSBQRWNXDTRK-UHFFFAOYSA-N

物化性质

• 沸点：
  369.53°C (estimate)
• 密度：
  0.8833 (rough estimate)
• 稳定性/保质期：
  存在于烟叶和烟气中。

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  20
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S36
• 危险类别码：
  R36/37/38
• 海关编码：
  2915900090

制备方法与用途

合成制备方法如下：

1. 从乙醇中得到结晶。
2. 在烟草中，其分类代码为FC15、OR44和26。

反应信息

• 作为反应物：
  描述：

  15-甲基十七烷酸 在 盐酸 、 4-二甲氨基吡啶 、 N,N'-二环己基碳二亚胺 作用下， 以 四氯化碳 为溶剂， 反应 0.17h， 生成 15-Methyl-heptadecanoic acid 2,3-dihydroxy-propyl ester
  参考文献：
  名称：

  Synthesis of 1-Monoglycerides Having C11-20 Branched Chain Fatty Acids and Their Hemolysis Effects.

  摘要：

  DOI：

  10.7164/antibiotics.52.345
• 作为产物：
  描述：

  undecanoic acid chloride monomethyl ester 在 一水合肼 、 diethylene glycol monosodium salt 、 二乙二醇 作用下， 生成 15-甲基十七烷酸
  参考文献：
  名称：

  Branched-Chain Fatty Acids. XX. Synthesis of Compounds useful for Relating Melting Point to Structure

  摘要：

  DOI：

  10.1021/jo50002a002

文献信息

• Oil-based cosmetic preparation
  申请人：Gotou Naoki

  公开号：US20060051307A1

  公开（公告）日：2006-03-09

  An oil-based cosmetic preparation contains (a) an oily gelling agent, (b) an oil-based ingredient, and (c) at least one selected from the group consisting of ester compounds represented by formula (I) which are reaction products of ditrimethylolpropane with fatty acid, polycondensates of ditrimethylolpropane with polycarboxylic acid, polycondensates of the ester compound of formula (I) with polycarboxylic acid, polycondensates of fatty acid with the polycondensate of ditrimethylolpropane with polycarboxylic acid, and polycondensates of ditrimethylolpropane, fatty acid and polycarboxylic acid, with the component (c) having a hydroxyl value (OHV) in the range of 10 to 150. The oil-based cosmetic preparation has excellent feeling realized by the use, provides a make-up coverage with satisfactory luster and moisturizing feel, and exhibits excellent shape retention properties.

  一种油基化妆品制剂包含(a)一种油性凝胶剂，(b)一种油性成分，以及(c)至少从由式(I)表示的酯化合物组成的群体中选择的一种，该酯化合物是二三甲基丙烷与脂肪酸的反应产物，二三甲基丙烷与多羧酸的聚缩物，式(I)的酯化合物与多羧酸的聚缩物，脂肪酸与二三甲基丙烷与多羧酸的聚缩物的酯化合物的聚缩物，以及二三甲基丙烷、脂肪酸和多羧酸的聚缩物，其中组分(c)具有羟值（OHV）在10至150之间。该油基化妆品制剂具有优异的感觉，提供具有令人满意的光泽和保湿感的化妆覆盖，并表现出优异的保形性能。
• Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use
  申请人：Sankyo Company Limited

  公开号：EP0536936A1

  公开（公告）日：1993-04-14

  Compounds of formula (I): [in which: R¹, R² and R³ are the same or different and each represents a hydrogen atom, an optionally substituted alkanoyl group or an alkenylcarbonyl group, provided that at least one of R¹, R² and R³ represents an unsubstituted alkanoyl group having from 5 to 24 carbon atoms, said substituted alkanoyl group or said alkenylcarbonyl group; and one of R⁴ and R⁵ represents a hydrogen atom and the other represents a cyano group]; have valuable anti-tumour activity.

  式子（I）的化合物：[其中：R¹、R²和R³相同或不同，每个代表氢原子、可选取代的脂肪酰基团或烯基羰基团，前提是至少有一个R¹、R²和R³代表有5到24个碳原子的未取代脂肪酰基团，或者是所述取代的脂肪酰基团或所述烯基羰基团；R⁴和R⁵中的一个代表氢原子，另一个代表氰基]，具有有价值的抗肿瘤活性。
• METHOD FOR PRODUCING CROSS-COUPLING COMPOUND
  申请人：Fujimori Taketoshi

  公开号：US20100048929A1

  公开（公告）日：2010-02-25

  To provide a method for performing a cross-coupling reaction of a Grignard compound with an alkyl halide simply, efficiently and in high yield, a method for obtaining a ω-bromo long chaincarboxylic acid simply and efficiently using an easily obtainable raw material and a method for producing a useful branched fatty acid simply and efficiently. [R 1 : an alkyl group having 1 to 15 carbon atoms, R 2 : an alkyl group having 1 to 30 carbon atoms with a carboxyl group and X and X′: a halogen atom] [n: an integer of 9 to 17] [n: an integer of 9 to 17, R 1a : a branched alkyl group having 3 to 8 carbon atoms and X: a halogen atom]

  提供一种简单、高效、高产率的格氏试剂与卤代烷进行交叉偶联反应的方法，以简单、高效的方式利用易得原料获得ω-溴长链羧酸的方法，以及以简单、高效的方式生产有用的支链脂肪酸的方法。[R1：具有1至15个碳原子的烷基，R2：具有1至30个碳原子的烷基，带有羧基，X和X'：卤素原子][n：9至17的整数][n：9至17的整数，R1a：具有3至8个碳原子的支链烷基，X：卤素原子]
• Fuel compositions
  申请人：The Lubrizol Corporation

  公开号：EP0388991A1

  公开（公告）日：1990-09-26

  Fuel compositions for internal combustion engines, and more particularly, fuel compositions for use in fuel-injected internal combustion engines are described. The fuel compositions comprise a major amount of a liquid hydrocarbon fuel and a minor, property-improving amount of a hydrocarbon-soluble dispersant prepared generally by the post-treatment of a nitrogen-containing composition with mono- and polycarboxylic acids which may be aliphatic or aromatic carboxylic acids although aromatic polycarboxylic acids are preferred. The nitrogen-containing compositions which are post-treated in accordance with the present invention are obtained by reacting an acylating agent with alkylene polyamines or alkanol amines. When fuel conpositions of the present invention are utilized in internal combustion engines, and in particular, fuel-injected internal combustion engines, the amount of solid deposits of the various parts of the internal combustion engines are reduced. In particular, the use of such fuels prevents or reduces intake system deposits and injector nozzle deposits. Accordingly, methods for reducing or preventing the buiid-up of deposits in internal combustion engines also are described.

  本文描述了用于内燃机的燃料组合物，特别是用于燃油喷射内燃机的燃料组合物。这些燃料组合物包括主要量的液态碳氢化合物燃料和少量的可改善性能的碳氢化合物可溶性分散剂，后者一般是通过用单羧酸和多羧酸对含氮组合物进行后处理而制备的，单羧酸和多羧酸可以是脂肪族或芳香族羧酸，但芳香族多羧酸更可取。根据本发明进行后处理的含氮组合物是通过酰化剂与亚烷基多胺或烷醇胺反应获得的。将本发明的燃料组合物用于内燃机，特别是喷射式内燃机时，可减少内燃机各部件的固体沉积物。特别是，使用这种燃料可以防止或减少进气系统沉积物和喷油器喷嘴沉积物。因此，还介绍了减少或防止内燃机沉积物形成的方法。
• Emulsifiers and explosive emulsions containing same
  申请人：The Lubrizol Corporation

  公开号：EP0408838A1

  公开（公告）日：1991-01-23

  Emulsifiers are disclosed which comprise the reaction product of component (I) with component (II). Component (I) comprises the reaction product of certain carboxylic acids or anhydrides, or ester or amide derivatives thereof, with ammonia, at least one amine, at least one alkali and/or at least one alkaline-earth metal Component (II) comprises certain phosphorus-containing acids; or metal salts of said phosphorus-containing acids, the metals being selected from the group consisting of magnesium, calcium, strontium, chromium, manganese, iron, molybdenum, cobalt, nickel, copper, silver, zinc, cadmium, aluminum, tin, lead, and mixtures of two or more thereof. These emulsifiers are useful in water-in-oil explosive emulsions.

  已公开的乳化剂包括组分(I)与组分(II)的反应产物。组分（I）包括某些羧酸或酸酐，或其酯或酰胺衍生物与氨、至少一种胺、至少一种碱和/或至少一种碱土金属的反应产物；或所述含磷酸的金属盐，这些金属选自镁、钙、锶、铬、锰、铁、钼、钴、镍、铜、银、锌、镉、铝、锡、铅和其中两种或两种以上金属的混合物组成的组。这些乳化剂可用于油包水型爆炸乳剂。