16-甲基十七烷酸叔丁酯 | 31478-84-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 16-甲基十七烷酸叔丁酯
• 中文别名: 异硬脂酸异丙酯；异十八烷酸1-甲基乙基酯
• 英文名称: Isopropyl isostearate
• 英文别名: propan-2-yl 16-methylheptadecanoate
• CAS: 31478-84-9；68171-33-5
• 化学式: C₂₁H₄₂O₂
• 分子量: 326.6
• InChiKey: NEOZOXKVMDBOSG-UHFFFAOYSA-N

物化性质

• 沸点：
  360.7±10.0 °C(Predicted)
• 密度：
  0.860±0.06 g/cm3(Predicted)
• LogP：
  9.135 (est)
• 物理描述：
  Liquid

计算性质

• 辛醇/水分配系数(LogP)：
  9
• 重原子数：
  23
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.952
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  16-甲基十七烷酸叔丁酯 、 氢气 在 Chromium(Cr) Copper crude product 作用下， 80.0~275.0 ℃ 、10.66 kPa 条件下， 反应 7.0h， 以thereby obtaining 3300 g of a colourless transparent isostearyl alcohol as a distillate at 80° to 167° C./0.6 mmHg的产率得到异硬脂醇
  参考文献：
  名称：

  .alpha.-Mono (methyl-branched alkyl) glyceryl ether and a skin care

  摘要：

  本发明公开了一种以公式##STR1##表示的.alpha.单(甲基支链烷基)甘油醚，其中m为2到14的整数，n为3到11的整数，m+n的总和为11到17，以及含有该甘油醚作为乳化剂的皮肤护理组合物。

  公开号：

  US04634719A1

文献信息

• Novel polyol ether compounds, process preparing the compounds, and
  申请人：KAO Corporation

  公开号：US04576967A1

  公开（公告）日：1986-03-18

  Triglycerine monoalkyl ethers of the general formula (I), which are novel polyol ether compounds, ##STR1## in which R represents a saturated or unsaturated, linear or branched fatty hydrocarbon group having from 8 to 24 carbon atoms. The ethers (I) of the present invention are prepared from firstly subjecting 1,3-bis-o-(2,3-o-isopropylideneglyceryl)glycerine (II) and an etherifying agent (IV) to Williamson's ether synthesis reaction, and the resulting 1,3-bis-o-(2,3-o-isopropylideneglyceryl)-2-o-alkylglycerine (III) is subsequently subjected to hydrolysis. The ethers according to the invention are chemically stable because no linkages susceptible to decomposition, e.g. ester bond, are contained in the molecular structure of the ethers. Moreover, the ethers give a reduced degree of stimulus to the skin and have the surface activity, so that they are useful as an emulsifier, oil (emolient), humectant, thickener and particularly as a component of cosmetics.

  本发明提供了一种新型的多元醇醚化合物，即一般式(I)的甘油单烷基醚，其中R代表具有8至24个碳原子的饱和或不饱和的线性或支链脂肪烃基。本发明的醚(I)是通过首先将1,3-双-o-(2,3-o-异丙基亚甘基)甘油(II)和醚化剂(IV)进行Williamson醚合成反应制备的，随后将得到的1,3-双-o-(2,3-o-异丙基亚甘基)-2-o-烷基甘油(III)进行水解。本发明的醚具有化学稳定性，因为醚的分子结构中不含易分解的化学键，例如酯键。此外，本发明的醚对皮肤的刺激程度降低，并具有表面活性，因此它们可用作乳化剂、油类(润肤剂)、保湿剂、增稠剂，特别是化妆品成分。
• Polyol ether compound, preparation process thereof, and cosmetic
  申请人：Kao Corporation

  公开号：US04543258A1

  公开（公告）日：1985-09-24

  Disclosed is a polyol ether compound represented by the general formula (I): ##STR1## in which R represents a saturated or unsaturated, straight-chain or branched aliphatic hydrocarbon group having 8 to 24 carbon atoms, and R' represents a saturated or unsaturated, straight-chain or branched hydrocarbon group having 1 to 24 carbon atoms. A preparation process of the compound (I) is also disclosed. Compounds according to the invention show excellent emulsification stability and are suitable to be a cosmetic composition.

  本发明揭示了一种由通式（I）表示的聚醚多元醇化合物：##STR1##其中，R代表具有8到24个碳原子的饱和或不饱和的直链或支链脂肪族碳氢基团，而R'代表具有1到24个碳原子的饱和或不饱和的直链或支链碳氢基团。本发明还揭示了化合物（I）的制备过程。根据本发明的化合物表现出优异的乳化稳定性，适合用作化妆品组合物。
• Alpha-mono(methyl-branched alkyl) glyceryl ether and a skin care cosmetic composition containing the same
  申请人：Kao Corporation

  公开号：EP0025302A1

  公开（公告）日：1981-03-18

  α-mono(methyl-branched alkyl) glyceryl ethers represented by the formula where m is an integer of 2 to 14, n is an integer of 3 to 11, and the total of m + n is 1 1 to 17, are disclosed along with skin care compositions containing the same as emulsifiers.

  α-单(甲基支链烷基)甘油醚由式 其中 m 为 2 至 14 的整数，n 为 3 至 11 的整数，m+n 的总和为 1 1 至 17。
• A water-in-oil type cosmetic composition and an emulsifier composition
  申请人：Kao Corporation

  公开号：EP0025654A2

  公开（公告）日：1981-03-25

  A water-in-oil type cosmetic composition comprising a cosmetic oil base material, water and a specific emulsifier are disclosed. The specific emulsifier comprising the following three components: (1) 94 to 43% by weight of a-mono (methyl-branched alkyl) glyceryl ether represented by the formula (I): where, R is a methyl-branched saturated hydrocarbon group having 14 to 20 carbon atoms; (2) 0.4 to 9.8% by weight of a multi-valent metal salt of a saturated or unsaturated aliphatic acid having 10 to 22 carbon atoms; and (3) 8 to 54% by weight of at least one inorganic or organic salt having a solubility in water of at least 0.2 g per 100 g of water at 20°C.

  本发明公开了一种油包水型化妆品组合物，它由化妆品油基材料、水和特定乳化剂组成。特定乳化剂由以下三种成分组成： (1) 94%至 43%（按重量计）由式（I）代表的 a-单（甲基支链烷基）甘油醚： 其中，R 是具有 14 至 20 个碳原子的甲基支链饱和烃基； (2) 0.4%至 9.8%（按重量计）具有 10 至 22 个碳原子的饱和或不饱和脂肪族 酸的多价金属盐；和 (3) 至少一种无机盐或有机盐，其重量百分比为 8%至 54%，在 20°C 时每 100 克水中的溶解度至少为 0.2 克。
• Cosmetic compositions as well as use of a cosmetic composition and method using same for removing waterproof make-up
  申请人：SCA Tissue France

  公开号：EP2921159A1

  公开（公告）日：2015-09-23

  The present invention relates to a use of a cosmetic composition for removing make-up, in particular waterproof make-up, wherein the cosmetic composition is in the form of a water-in-oil emulsion. The cosmetic composition, which is coated onto or impregnated into an applicator for cosmetic purpose, such as a pad, comprises an oil component having a polarity of at least 20 mN/m, water, and an emulsifier component comprising a lipophilic non-ionic emulsifier. According to another aspect, the invention relates to a method for removing make-up, especially waterproof make-up, comprising applying the above cosmetic composition to the skin. Further, the present invention is concerned with a specific cosmetic composition comprising water, an emulsifier component comprising a lipophilic non-ionic emulsifier, and an oil component which is a mixture of C12-C16 alkane and a cyclic silicone, in particular a cyclopentasiloxane and/or cyclohexasiloxane, and also to an applicator for cosmetic purpose impregnated or coated with such cosmetic composition. The present invention allows a highly efficient removal of waterproof make-up while reducing or avoiding the formation of an oily or greasy film with heavy texture on the skin upon use.

  本发明涉及一种用于卸妆，特别是卸防水妆的化妆品组合物，其中该化妆品组合物为油包水乳液形式。该化妆品组合物涂在或浸渍在用于化妆品的涂抹器（如化妆棉）上，包括极性至少为 20 mN/m 的油成分、水和乳化剂成分，乳化剂成分包括亲脂性非离子乳化剂。根据另一个方面，本发明涉及一种卸妆方法，尤其是卸防水妆的方法，包括将上述化妆品组合物涂在皮肤上。此外，本发明还涉及一种特定的化妆品组合物，该组合物包括水、由亲油性非离子乳化剂组成的乳化剂成分、以及由 C12-C16 烷烃和环状硅氧烷（尤其是环五硅氧烷和/或环己硅氧烷）组成的混合物油成分；本发明还涉及一种浸渍或涂覆有上述化妆品组合物的化妆品用涂抹器。本发明可以高效地卸除防水化妆品，同时减少或避免在使用时在皮肤上形成质地厚重的油性或油脂膜。

表征谱图