2(1H)-嘧啶酮,4-氨基-1-(2,3-二脱氧-2-甲基-b-D-苏-五呋喃糖基)- | 84393-31-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 2(1H)-嘧啶酮,4-氨基-1-(2,3-二脱氧-2-甲基-b-D-苏-五呋喃糖基)-
• 英文名称: γ-carboxypropylamide of linoleic acid
• 英文别名: GABA-linoleamide；Gabalid；4-[[(9Z,12Z)-octadeca-9,12-dienoyl]amino]butanoic acid
• CAS: 84393-31-7
• 化学式: C₂₂H₃₉NO₃
• 分子量: 365.557
• InChiKey: YGFYZZQGVSUXJE-HZJYTTRNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  26
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 海关编码：
  2924199090

反应信息

• 作为产物：
  描述：

  (Z,Z)-9,12-十八烷二烯酸二聚物 、 4-氨基丁酸 在 N-羟基丁二酰亚胺 、 N,N'-二环己基碳二亚胺 、 碳酸氢钠 作用下， 以 1,4-二氧六环 、 水 为溶剂， 反应 7.0h， 生成 2(1H)-嘧啶酮,4-氨基-1-(2,3-二脱氧-2-甲基-b-D-苏-五呋喃糖基)-
  参考文献：
  名称：

  Organic compounds

  摘要：

  一种包含符合式(I)的化合物或其可食用盐的风味组合物，其中R1是含有6至20个碳原子的烷基残基，或者含有9至25个碳原子且具有1至6个双键的烯烃残基，R1与其连接的羰基一起是羧酸的残基，NR2R3中，R3为H或与R2和它们连接的N原子一起是一个5元环的残基，是一种氨基酸的残基，特别是一种蛋白质原性氨基酸、鸟氨酸、γ-氨基丁酸或β-丙氨酸，或者是一种1-氨基环烷基羧酸的残基。

  公开号：

  US10836712B2

文献信息

• Improvements in or Relating to Organic Compounds
  申请人：GIVAUDAN SA

  公开号：US20160214928A1

  公开（公告）日：2016-07-28

  A stock solution comprising a compound of formula (I) Wherein R 1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and NR 2 R 3 , in which R 3 is H or together with R 2 and the N-atom to which they are attached, a 5-membered ring, is a residue of an amino acid, in particular a proteinogenic amino acid, ornithine, gamma-aminobutyric acid or beta alanine, or a 1-amino cycloalkyl carboxylic acid.

  一个包含化合物式(I)的原液溶液，其中R1与其连接的羰基共同构成羧酸残基，并且NR2R3，其中R3是H或与R2及它们连接的N原子共同构成一个5元环，是氨基酸的残基，特别是一种蛋白质原生氨基酸、鸟氨酸、γ-氨基丁酸或β-丙氨酸，或者是一种1-氨基环烷基羧酸。
• N-Acyl-Amino Acid Derivatives for Improvement of the Flavour Profile Edible Compositions
  申请人：Givaudan S.A.

  公开号：US20150086694A1

  公开（公告）日：2015-03-26

  The use of a compound according to formula (I) or the edible salts thereof in an edible composition to mask or modulate an undesired taste or off-taste contained in the edible composition wherein R 1 is an alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R 1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and NR 2 R 3 , in which R 3 is H or together with R 2 and the N-atom to which they are attached, a 5-membered ring, is a residue of an amino acid, in particular a proteinogenic amino acid, ornithine, gamma-aminobutyric acid or beta alanine, or a 1-amino cycloalkyl carboxylic acid.

  根据公式（I）或其可食用盐在可食用组合物中的使用，以掩盖或调节可食用组合物中所含的不良味道或异味，其中R1是含6至20个碳原子的烷基残基，或含有1至6个双键的9至25个碳原子的烯烃残基，R1与其附着的羰基基团一起是羧酸的残基，而NR2R3中，R3为H或与R2和它们所附着的N原子一起，形成一个5元环，是氨基酸的残基，特别是蛋白质原氨基酸、鸟氨酸、γ-氨基丁酸或β-丙氨酸，或1-氨基环烷基羧酸的残基。
• N-acyl derivatives of gamma amino-butyric acid and beta alanine as food flavouring compounds
  申请人：Givaudan S.A.

  公开号：US10645955B2

  公开（公告）日：2020-05-12

  A flavour composition comprising a compound according to the formula (I) and edible salts thereof, wherein R1 is an alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and m is 0 or 1.

  一种香料组合物，包含符合式（I）的化合物 及其食用盐、 其中 R1 是含有 6 至 20 个碳原子的烷基残基，或含有 9 至 25 个碳原子并带有 1 至 6 个双键的烯基残基，R1 与所连接的羰基一起是羧酸残基，以及 m 为 0 或 1。
• N-acyl-amino acid derivatives for improvement of the flavor profile of edible compositions
  申请人：Givaudan S.A.

  公开号：US10856563B2

  公开（公告）日：2020-12-08

  The use of a compound according to formula (I) or the edible salts thereof in an edible composition to mask or modulate an undesired taste or off-taste contained in the edible composition wherein R1 is an alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and NR2R3, in which R3 is H or together with R2 and the N-atom to which they are attached, a 5-membered ring, is a residue of an amino acid, in particular a proteinogenic amino acid, ornithine, gamma-aminobutyric acid or beta alanine, or a 1-amino cycloalkyl carboxylic acid.

  在可食用组合物中使用式(I)化合物或其食用盐，以掩盖或调节可食用组合物中所含的不良味道或异味 其中 R1 是含有 6 至 20 个碳原子的烷基残基，或含有 9 至 25 个碳原子并带有 1 至 6 个双键的烯基残基，R1 与所连接的羰基一起是羧酸残基，以及 NR2R3、是氨基酸残基，特别是蛋白氨基酸、鸟氨酸、γ-氨基丁酸或 β-丙氨酸，或 1-氨基环烷基羧酸。
• In or relating to organic compounds
  申请人：Givaudan SA

  公开号：US11524933B2

  公开（公告）日：2022-12-13

  A flavour composition comprising a compound according to the formula (I) or edible salts thereof, wherein R 1 is alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R 1 together with the carbonyl to which it is attached is a residue carboxylic acid, and NR 2 R 3 , in which R 3 is H or together with R 2 and the N-atom to which they are attached, a 5-membered ring, is a residue of an amino acid, in particular proteinogenic amino acid, ornithine, gamma-aminobutyric acid or beta alanine, or a 1-amino cycloalkyl carboxylic acid.

  一种香料组合物，包含根据式 (I) 的化合物或其食用盐、 其中 R 1 是含有 6 至 20 个碳原子的烷基残基，或含有 9 至 25 个碳原子并带有 1 至 6 个双键的烯基残基，R 1 连同其所连接的羰基是羧酸残基，而 NR 2 R 3 ，其中 R 3 是 H 或与 R 2 是氨基酸残基，特别是蛋白氨基酸、鸟氨酸、γ-氨基丁酸或 β-丙氨酸，或 1-氨基环烷基羧酸。