2,2'-(3-硝基苯基亚氨基)-二乙醇 | 24812-82-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,2'-(3-硝基苯基亚氨基)-二乙醇
• 英文名称: 3-[N,N-Bis(2-hydroxyethyl)amino]nitrobenzene
• 英文别名: N,N-di(2-hydroxyethyl)-3-nitrobenzeneamine；N,N-bis-(2-hydroxyethyl)-3-nitroaniline；N,N-bis(2-hydroxyethyl)-3-nitroaniline；m-[N,N-bis(2-hydroxyethyl)amino]nitrobenzene；N,N-bis-(2-hydroxy-ethyl)-3-nitro-aniline；N,N-Bis-(2-hydroxy-aethyl)-3-nitro-anilin；Ethanol, 2,2'-[(3-nitrophenyl)imino]bis-；2-[N-(2-hydroxyethyl)-3-nitroanilino]ethanol
• CAS: 24812-82-6
• 化学式: C₁₀H₁₄N₂O₄
• mdl: MFCD00043605
• 分子量: 226.232
• InChiKey: CMFNTWPAEFXJIU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  89.5
• 氢给体数：
  2
• 氢受体数：
  5

安全信息

• 海关编码：
  2922199090

反应信息

• 作为反应物：
  描述：

  2,2'-(3-硝基苯基亚氨基)-二乙醇 在 吡啶 、 盐酸 、 tin(ll) chloride 、 三氯氧磷 作用下， 生成 Ethyl-N-m-(bis-2-chlorethylamino)-phenylcarbamat
  参考文献：
  名称：

  细胞毒性化合物。部分X.氨基甲酸酯衍生自NN -二- （2-氯乙基）米-和NN -双- （2-氯乙基） - p苯二胺

  摘要：

  通过使胺m -RNH 2或对-RNH 2 [R = C 6 H 4 ·N（CH 2 ·CH 2 Cl）2 ]与氯甲酸酯反应制备氨基甲酸酯。该产品，除去保护基团后，包括p -RNH·CO·O·C ^ 6 ħ 4 ·CO 2 H（ø - ，米- ，和p - ），米-RNH·CO·O·C ^ 6 ħ 4 ·CO 2 H（m -），O-（p-RNH·CO）-丝氨酸和O-（p -RNH·CO）-苏氨酸。对苯二甲酸酰胺，（p -RNH·CO）2 C ^ 6 ħ 4和（p -RNH·CO）C 6 H ^ 4 ·CO 2 Me和邻苯二甲酰亚胺，C 6 H ^ 4（CO）2 NR（米-和p - ），也有介绍。

  DOI：

  10.1039/j39700000472
• 作为产物：
  描述：

  间硝基苯胺 、 2-氯乙醇 在 calcium carbonate 、 potassium iodide 作用下， 生成 2,2'-(3-硝基苯基亚氨基)-二乙醇
  参考文献：
  名称：

  Synthesis, crystal structure and biological activity of novel diester cyclophanes

  摘要：

  A series of novel diester cyclophanes was synthesized by esterification of 1,2-benzenedicarbonyl chloride with eight different diols under high dilution conditions. The structures of the compounds were verified by elemental analysis, H-1 nuclear magnetic resonance (NMR), IR spectroscopy and high resolution mass spectrometry (HRMS). The crystal structures of two compounds were characterized by single crystal X-ray diffractometry (XRD). All the new cyclophanes were evaluated for biological activities and the results showed that some of these compounds have low antibacterial or antifungal activities.

  DOI：

  10.1590/s0103-50532012005000045

文献信息

• Laundry Care Composition Comprising Carboxylate Dye
  申请人：Milliken & Company

  公开号：US20150080561A1

  公开（公告）日：2015-03-19

  The present invention relates to laundry care compositions comprising carboxylate dyes. The laundry care compositions can be laundry detergent compositions, laundry additive compositions such as fabric enhancer compositions or bleach additive compositions. Preferably, the laundry care composition is a laundry detergent composition. The composition can be a solid, such as a powder, tablet or bar, or a liquid. The composition can be in the form of a unit dose, such as pouch. Suitable unit dose pouches include single compartment and multi-compartment pouches.

  本发明涉及包含羧酸盐染料的洗涤护理组合物。洗涤护理组合物可以是洗涤剂组合物，洗涤添加剂组合物，如织物增良剂组合物或漂白剂添加剂组合物。最好，洗涤护理组合物是洗涤剂组合物。该组合物可以是固体，如粉末、片剂或条形，也可以是液体。该组合物可以是单剂形式，如袋装。适用的单剂袋包括单隔室和多隔室袋。
• COSMETIC COMPOSITION
  申请人：Knappe Thorsten

  公开号：US20100028272A1

  公开（公告）日：2010-02-04

  A cosmetic agent, in particular a styling agent, containing, in a cosmetically acceptable carrier, a) at least one copolymer A made of at least one monomer A1 selected from acrylic acid, methacrylic acid, acrylic acid alkyl esters, and methacrylic acid alkyl esters, and at least one amphoteric monomer A2 selected from (meth)acryloylalkylbetaines of formula (A2-I) and (meth)acryloylalkylamine oxides of formula (A2-II), such that in formula (A2-I) and in formula (A2-II), R 1 denotes H or CH 3 , R 2 and R 3 , mutually independently in each case, denote optionally branched C 1-10 alkyl, and n denotes an integer from 1 to 20, and b) at least one film-forming and/or setting amphoteric polymer B different from copolymer A; and use of the agents for the temporary deformation of hairs.

  一种化妆品剂，特别是一种造型剂，包含在一种在化妆上可接受的载体中，a) 至少一种由至少一种从丙烯酸、甲基丙烯酸、丙烯酸烷基酯和甲基丙烯酸烷基酯中选择的单体A1制成的共聚物A，以及至少一种从式（A2-I）的（甲基）丙烯酰烷基甜菜碱和式（A2-II）的（甲基）丙烯酰烷基胺氧中选择的两性单体A2，使得在式（A2-I）和式（A2-II）中，R1代表H或CH3，R2和R3，在每种情况下相互独立地表示可选的支链C1-10烷基，n代表1到20之间的整数，以及b) 至少一种与共聚物A不同的成膜和/或固定两性聚合物B；以及使用这些剂对头发进行暂时变形。
• Benzimidazole derivatives
  申请人：Mitsui Chemicals, Inc.

  公开号：US05852011A1

  公开（公告）日：1998-12-22

  Disclosed are compounds represented by the following chemical formula (I) and pharmacologically acceptable salts thereof which are novel compounds useful as anticancer agents, antiviral agents or antimicrobial agents. ##STR1##

  以下是化学式（I）表示的化合物及其药理学上可接受的盐，它们是一种新型化合物，可作为抗癌剂、抗病毒剂或抗微生物剂使用。
• Phenylbenzimidazole derivatives
  申请人：Mitsui Chemicals, Inc.

  公开号：US05821258A1

  公开（公告）日：1998-10-13

  Described herein is an anticancer agent, an antiviral agent or an antimicrobial agent which contains, as an active ingredient for acting on DNA, a compound presented by the following formula (1) or its pharmacologically acceptable salt: ##STR1##

  本文描述了一种抗癌剂、抗病毒剂或抗微生物剂，其包含作用于DNA的活性成分，该活性成分由以下化学式（1）或其药理学上可接受的盐所表示：##STR1##
• SUBSTANCES FOR DYEING KERATINOUS FIBERS
  申请人：Gross Wibke

  公开号：US20100037909A1

  公开（公告）日：2010-02-18

  Disclosed are substances which contain unsaturated, non-aromatic dialdehydes of formula (Ia) and/or the tautomer (Ib) thereof, wherein R 1 , R 2 , and R 3 are defined as indicated in claim 1 , along with at least one CH-acidic compound of formulas (II) and/or (III), wherein R 6 , R 7 , R 8 , R 9 , R 10 , Y, X − , Het, and X 1 are defined as indicated in claim 1 , in a cosmetic carrier. Said substances color keratinous fibers, especially human hair, in an intensive, colorfast, natural brown shade.

  本发明涉及一种含有式(Ia)和/或其互变异构体(Ib)的不饱和非芳香二醛的物质，其中R1、R2和R3如权利要求1所示定义，以及至少一种式(II)和/或(III)的CH-酸性化合物，其中R6、R7、R8、R9、R10、Y、X−、Het和X1如权利要求1所示定义，在一种化妆品载体中。所述物质能够使角质纤维，尤其是人类头发，在一种浓郁、色牢、自然棕色的色调中着色。

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