2,2,3,3,4,4-六氟丁酸甲酯 | 356-32-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2,2,3,3,4,4-六氟丁酸甲酯
• 英文名称: methyl 2,2,3,3,4,4-hexafluorobutyrate
• 英文别名: 1-Monohydrogenperfluor-n-buttersaeuremethylester；Methyl 2,2,3,3,4,4-hexafluorobutanoate
• CAS: 356-32-1
• 化学式: C₅H₄F₆O₂
• mdl: MFCD00465645
• 分子量: 210.076
• InChiKey: GUDSBACGSFZSPH-UHFFFAOYSA-N

物化性质

• 沸点：
  113 °C
• 密度：
  1.422±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  8

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S37/39
• 危险类别码：
  R36/37/38
• 海关编码：
  2915900090

SDS

Name:	Methyl 2,2,3,3,4,4-hexafluorobutanoate, 97% Material Safety Data Sheet
Synonym:
CAS:	356-32-1

Section 1 - Chemical Product MSDS Name: Methyl 2,2,3,3,4,4-hexafluorobutanoate, 97% Material Safety Data Sheet
Synonym:

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SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
356-32-1	Methyl 2,2,3,3,4,4-hexafluorobutanoate	97%	unlisted

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Hazard Symbols: XI

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SECTION 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

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SECTION 4 - FIRST AID MEASURES
Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

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SECTION 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

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SECTION 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.

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SECTION 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

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SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 356-32-1: Personal Protective Equipment
Eyes:
Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: colorless
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 113 - 115 deg C @760mmHg
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C5H4F6O2
Molecular Weight: 210

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SECTION 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, acrid smoke and fumes, fluorine, hydrogen fluoride gas.
Hazardous Polymerization: Has not been reported

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SECTION 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 356-32-1 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Methyl 2,2,3,3,4,4-hexafluorobutanoate - Not listed by ACGIH, IARC, or NTP.

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SECTION 12 - ECOLOGICAL INFORMATION

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SECTION 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations.

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SECTION 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available.

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SECTION 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 356-32-1: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 356-32-1 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 356-32-1 is not listed on the TSCA inventory. It is for research and development use only.

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SECTION 16 - ADDITIONAL INFORMATION
MSDS Creation Date: 3/21/2003 Revision #0 Date: Original. The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为产物：
  描述：

  六氟戊二酸单甲酯 在 sodium methylate 作用下， 以 甲醇 、 乙腈 为溶剂， 生成 2,2,3,3,4,4-六氟丁酸甲酯
  参考文献：
  名称：

  Berenblit,V.V. et al., Journal of Organic Chemistry USSR (English Translation), 1974, vol. 10, p. 2525 - 2528

  摘要：

  DOI：

文献信息

• Electrocarboxylation of α,ω-dihaloperfluoroalkanes and of perfluoroalkylhalides in a near-critical and supercritical CO2-methanol medium
  作者：V.M. Mazin、E.I. Mysov、S.R. Sterlin、V.A. Grinberg

  DOI：10.1016/s0022-1139(97)00131-0

  日期：1998.2

  The electrocatalytical carboxylations of some perfluoroalkylhalides and alpha,omega-dihaloperfluoroalkanes on copper and stainless steel electrodes in near-and supercritical CO2-methanol mixtures have been investigated, The main products and intermediates were determined, It was shown that the differences in the composition of products in these two cases indicate quite different catalytic activities of copper and stainless steel electrodes with regard to the electroreduction reactions of the intermediates and quite different adsorptions of these intermediates on the surfaces of the electrodes. (C) 1998 Elsevier Science S.A. All rights reserved.
• Yuminov, Russian Journal of Organic Chemistry, 1998, vol. 34, # 12, p. 1715 - 1720
  作者：Yuminov

  DOI：——

  日期：——
• Berenblit,V.V. et al., Journal of Organic Chemistry USSR (English Translation), 1974, vol. 10, p. 2525 - 2528
  作者：Berenblit,V.V. et al.

  DOI：——

  日期：——