2,2,4,4,5,5-六溴联苯醚 | 68631-49-2

• 物质功能分类: 分析化学 - 标准品 - 有机污染物标样
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,2,4,4,5,5-六溴联苯醚
• 英文名称: 2,2',4,4',5,5'-hexabromobiphenyl ether
• 英文别名: BDE-153；2,2',4,4',5,5'-hexabrominated diphenyl ether；2,2',4,4',5,5'-tetrabromodiphenyl ether；2,2',4,4',5,5'-Hexabromodiphenyl ether；2,2',4,4',5,5'-hexabromo diphenylether；2,4,5,2',4',5'-hexabromodiphenyl ether；1,2,4-tribromo-5-(2,4,5-tribromophenoxy)benzene
• CAS: 68631-49-2
• 化学式: C₁₂H₄Br₆O
• 分子量: 643.587
• InChiKey: RZXIRSKYBISPGF-UHFFFAOYSA-N

物化性质

• 沸点：
  453 °C
• 密度：
  2.502±0.06 g/cm3(Predicted)
• 闪点：
  -12 °C
• 溶解度：
  可溶于氯仿（少量）、乙酸乙酯（少量）
• 物理描述：
  Solid
• 熔点：
  157.6°C
• 碰撞截面：
  182.9 Ų [M-Br+O]-

计算性质

• 辛醇/水分配系数(LogP)：
  7.6
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 危险品标志：
  Xn,F,N
• 安全说明：
  S16,S29,S33,S60,S61,S62,S9
• 危险类别码：
  R11,R38,R50/53,R65,R67
• WGK Germany：
  2
• 危险品运输编号：
  UN 1262 3/PG 2

反应信息

• 作为产物：
  描述：

  2,4,5-三溴-苯酚 在 silica-alumina 作用下， 反应 0.5h， 以79%的产率得到2,2,4,4,5,5-六溴联苯醚
  参考文献：
  名称：

  一种多溴联苯醚单体的固相合成方法与应用

  摘要：

  本发明公开了一种多溴联苯醚单体的固相合成方法与应用，其解决了现有技术中对于多溴联苯醚的合成方法反应时间长、试剂腐蚀性大、后处理繁琐以及需要特制设备的问题，具有采用在研磨条件下固体超强酸催化合成多溴联苯醚的方法，避免使用强碱强酸性液体试剂，安全性高且清洁环保；合成时间为10‑30分钟，较“碘鎓盐‑偶联两步反应法”的反应时间大大缩短的效果。其技术方案为：包括如下步骤：溴代苯酚在固体超强酸的催化下发生脱水偶联反应，即得多溴联苯醚单体。

  公开号：

  CN106957218B

文献信息

• 一种多溴联苯醚单体的微波合成方法
  申请人：山东省分析测试中心

  公开号：CN104860799B

  公开（公告）日：2016-10-12

  本发明公开了一种多溴联苯醚单体的微波合成方法，溴代苯在蒙脱土的催化下与溴代苯酚反应，反应产物经提纯分离后，即得多溴联苯醚。其设备简单，化学反应彻底且安全无污染。避免使用强碱强酸性试剂，安全性高且清洁环保；本发明为一步反应，合成时间为20～60分钟，较“碘鎓盐‑偶联两步反应法”反应反应时间大大缩短；微波功率在130～300瓦，其能耗较低。
• Highly unsaturated fatty acid or highly unsaturated fatty acid ethyl ester with reduced environmental pollutants, and method for producing same
  申请人：NIPPON SUISAN KAISHA, LTD.

  公开号：US10399922B2

  公开（公告）日：2019-09-03

  A highly unsaturated fatty acid or a highly unsaturated fatty acid ethyl ester that has been produced using as a feedstock oil a fat or oil that contains highly unsaturated fatty acids as constituent fatty acids and which has been reduced in the contents of environmental pollutants, wherein among the dioxins contained, polychlorinated dibenzoparadioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are contained in amounts of less than 0.05 pg-TEQ/g and coplanar PCBs (Co-PCBs) in amounts of less than 0.03 pg-TEQ/g. Also disclosed is a method for producing the highly unsaturated fatty acid or highly unsaturated fatty acid ethyl ester by the steps of removing free fatty acids and environmental pollutants by thin-film distillation from a feedstock oil, ethyl esterifying the resulting fat or oil, and refining the same by rectification and column chromatography.

  一种高度不饱和脂肪酸或高度不饱和脂肪酸乙酯，它是以含有高度不饱和脂肪酸作为组成脂肪酸的脂肪或油作为原料油生产的，其环境污染物含量已经降低，其中所含的二恶英中，多氯二苯并对二恶英（PCDD）和多氯二苯并呋喃（PCDF）的含量低于 0.05 pg-TEQ/g，共面多氯联苯（Co-PCB）的含量低于 0.03 pg-TEQ/g。05 pg-TEQ/g，共面多氯联苯（Co-PCBs）含量低于 0.03 pg-TEQ/g。本发明还公开了一种生产高度不饱和脂肪酸或高度不饱和脂肪酸乙酯的方法，其步骤是通过薄膜蒸馏法从原料油中去除游离脂肪酸和环境污染物，对所得脂肪或油进行乙酯化，并通过精馏和柱层析法对其进行精制。
• Oern, Ulrika; Eriksson, Lars; Jakobsson, Eva, Acta Chemica Scandinavica, 1996, vol. 50, p. 802 - 807
  作者：Oern, Ulrika、Eriksson, Lars、Jakobsson, Eva、Bergman, Ake

  DOI：——

  日期：——
• Residues of Polybrominated Diphenyl Ethers in Honeys from Different Geographic Regions
  作者：Jun Wang、Michael M. Kliks、Soojin Jun、Qing X. Li

  DOI：10.1021/jf904490g

  日期：2010.3.24

  Polybrominated diphenyl ethers (PBDEs) are a class of widely used flame-retardants. Fifty honey samples labeled as being from different countries and regions were analyzed for 27 PBDE congeners. The concentrations of the 26 PBDEs, excluding BDE-209, ranged from 300 to 10,550 pg/g while the concentrations of BDE-209 ranged from nondetected to 9,260 pg/g. The honey samples labeled as originating in developed countries generally displayed higher concentrations of the total 27 PBDEs than those labeled as being from developing countries. Concentrations of 26 PBDEs ranged from 2,720 to 10,550 pg/g in honeys originating in developed countries and ranged from 1,030 to 3,470 pg/g in those from developing countries. BDE-209 was a dominant PBDE congener in all honey samples, on average accounting for 16% and 65% of the total 27 P8DEs in honeys from developed and developing countries, respectively. Honeys originating in developing countries, however, showed much higher BDE-209 levels and higher ratios of BDE-209 relative to the other PBDE congeners. In addition, some highly brominated PBDE congeners such as BDE196, -197, -206, and -207 showed elevated concentrations in honeys from developing countries. The findings were in agreement with the long, heavy historical uses of PBDE products in developed countries and the current, heavy uses of BDE-209 in developing countries. When BDE-209 was fortified in honey and incubated in the dark for four weeks at 25 or 60 degrees C, BDE-153, -183, -206, and -207 were detected as debromination products of BDE-209. Less brominated congeners in honeys may primarily come from the environment. Debromination of BDE-209 is also a source of less brominated congeners in honeys. The detection of PBDEs in honeys suggests that human exposure to PBDEs occurs as a result of honey consumption.
• MEMBRANE-BASED PROCESSES FOR REDUCING AT LEAST ONE IMPURITY AND MAKING A CONCENTRATE COMPRISING AT LEAST ONE NATURAL COMPONENT FROM A NON-MARINE FATTY ACID OIL MIXTURE, AND COMPOSITIONS RESULTING THEREOF
  申请人：Evonik Membrane Extraction Technology Limited

  公开号：EP2776544A1

  公开（公告）日：2014-09-17