The present invention relates generally to proteasome inhibiting β-lactam compounds useful for the treatment of cancer and neurodegenerative disorders. The invention also provides pharmaceutical compositions and extended release formulations of said compounds, and medical uses of said compounds and/or pharmaceutical compositions to treat cancer and neurodegenerative disorders.
本发明通常涉及抑制
蛋白酶体的β-内酰胺化合物,用于治疗癌症和神经退行性疾病。该发明还提供了所述化合物的药物组合物和延长释放配方,以及利用所述化合物和/或药物组合物治疗癌症和神经退行性疾病的医疗用途。