2,2-二氯-N,N-二甲基-3-氧代丁酰胺 | 22543-26-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2,2-二氯-N,N-二甲基-3-氧代丁酰胺
• 英文名称: 2,2-dichloro-acetoacetic acid dimethylamide
• 英文别名: 2,2-Dichlor-acetessigsaeure-dimethylamid；2,2-Dichlor-N,N-dimethyl-acetoacetamid；2,2-dichloro-N,N-dimethyl-3-oxobutyramide；2,2-dichloro-N,N-dimethyl-3-oxobutanamide
• CAS: 22543-26-6
• 化学式: C₆H₉Cl₂NO₂
• 分子量: 198.049
• InChiKey: VZYZILNMQDUERW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2924199090

反应信息

• 作为反应物：
  描述：

  三异丙基亚磷酸酯 、 2,2-二氯-N,N-二甲基-3-氧代丁酰胺 生成 Phosphonsaeure-(2-chlor-1-methyl-2-dimethylcarbamoyl-vinylester)-diisopropylester
  参考文献：
  名称：

  Polychlorinated ketones. III. Formation by acid-catalyzed cleavage of vinyl phosphates and phosphonates

  摘要：

  DOI：

  10.1021/jo01263a072

文献信息

• Fluorine compound and fluorinating agent comprising the compound
  申请人：——

  公开号：US20040073065A1

  公开（公告）日：2004-04-15

  A fluorine compound represented by Formula (1) is provided. The above fluorine compound is effective for introducing a fluorine atom into a compound having an active group such as an oxygen-containing functional group, and it can be used for uses of surface treatment, cleaning and coating. Further, after the fluorination reaction, the above compound is recovered and can be reused as a starting material for producing the above fluorine compound, and it is useful for various fluorination processes. 1 (wherein X represents a nitrogen or phosphorus atom; R 0 , R 1 , and R 2 represent hydrogen, an alkyl group or aryl group which may have a substituent, and they each may be the same or different; and R 0 , R 1 , and R 2 may be combined with each other to form a ring).

  提供一种由式（1）表示的氟化合物。上述氟化合物对于将氟原子引入具有活性基团（如含氧功能基团）的化合物是有效的，可用于表面处理、清洁和涂覆等用途。此外，在氟化反应后，上述化合物可以回收并作为生产上述氟化合物的起始物质进行再利用，对于各种氟化过程是有用的。其中X代表氮或磷原子；R0、R1和R2代表氢、烷基或芳基，可能带有取代基，它们各自可以相同也可以不同；R0、R1和R2可以相互结合形成环。
• FLUORINE COMPOUND AND FLUORINATING AGENT COMPRISING THE COMPOUND
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：EP1422216A1

  公开（公告）日：2004-05-26

  A fluorine compound represented by Formula (1) is provided. The above fluorine compound is effective for introducing a fluorine atom into a compound having an active group such as an oxygen-containing functional group, and it can be used for uses of surface treatment, cleaning and coating. Further, after the fluorination reaction, the above compound is recovered and can be reused as a starting material for producing the above fluorine compound, and it is useful for various fluorination processes. (wherein X represents a nitrogen or phosphorus atom; R0, R1, and R2 represent hydrogen, an alkyl group or aryl group which may have a substituent, and they each may be the same or different; and R0, R1, and R2 may be combined with each other to form a ring).

  本发明提供了一种由式（1）表示的氟化合物。上述氟化合物能有效地将氟原子引入具有含氧官能团等活性基团的化合物中，可用于表面处理、清洁和涂层等用途。此外，氟化反应后，上述化合物被回收，可作为生产上述氟化合物的起始原料再次使用，可用于各种氟化工艺。 (其中，X 代表氮原子或磷原子；R0、R1 和 R2 代表氢、烷基或芳基，它们可以具有取代基，它们可以相同或不同；R0、R1 和 R2 可以相互结合形成一个环）。
• PROCESS FOR PRODUCING ALPHA, ALPHA- DIFLUOROAMINE
  申请人：National University Corporation Hokkaido University

  公开号：EP1813596A1

  公开（公告）日：2007-08-01

  A process for producing an α,α-difluoroamine which comprises using hydrogen fluoride and a Lewis base in specific amounts in the halogen-fluorine exchange reaction using an α,α-dihaloamine as the substrate. The process can be industrially applied, enables to obtain the object compound in a short time at a great yield and can be conducted easily with excellent productivity.

  一种生产α,α-二氟化胺的工艺，包括在以α,α-二卤胺为底物的卤-氟交换反应中使用一定量的氟化氢和路易斯碱。该工艺可应用于工业，能在短时间内以高产率获得目标化合物，而且操作简便，生产效率极高。
• DE1098939
  申请人：——

  公开号：——

  公开（公告）日：——
• Verfahren zur Herstellung von Alpha-Chlor-N-monoalkyl-acetoacetamiden
  申请人：Wacker-Chemie GmbH

  公开号：EP0005849B1

  公开（公告）日：1981-10-21