2,3,4,6-四氯苯酚乙酸酯 | 5435-60-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 中文名称: 2,3,4,6-四氯苯酚乙酸酯
• 英文名称: 2,3,4,6-tetrachlorophenyl acetate
• 英文别名: acetic acid-(2,3,4,6-tetrachloro-phenyl ester)；Essigsaeure-(2,3,4,6-tetrachlor-phenylester)；2.3.4.6-Tetrachlor-1-acetoxy-benzol；(2.3.4.6-Tetrachlor-phenyl)-acetat；(2,3,4,6-tetrachlorophenyl) acetate
• CAS: 5435-60-9
• 化学式: C₈H₄Cl₄O₂
• 分子量: 273.931
• InChiKey: RHZFLXLMXCNOHX-UHFFFAOYSA-N

物化性质

• 保留指数：
  1617;1617;1617;1637;1611.1;1614.9

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2915390090

反应信息

• 作为产物：
  描述：

  溶剂黄146 、 2,3,4,6-四氯酚 在 氯磺酸 作用下， 反应 2.0h， 以78%的产率得到2,3,4,6-四氯苯酚乙酸酯
  参考文献：
  名称：

  Stepanenko, N. I.; Ryakhovskaya, A. I.; Romanenko, O. A., Journal of applied chemistry of the USSR, 1983, vol. 56, # 3, p. 660 - 661

  摘要：

  DOI：

文献信息

• METHOD FOR THE SYNTHESIS OF PENTA-PENDANT ENANTIOMER-PURE CHELATORS AND PROCESS FOR THERAPEUTICALLY ACTIVE BIOCONJUGATES PREPARATION BY A COVALENT BINDING THEREOF
  申请人：Benes Ivan

  公开号：US20090162290A1

  公开（公告）日：2009-06-25

  The present invention provides a method for synthesis and binding methods of pentapendant enantiomer-pure chelators of formula (VII) wherein R 1 , R 2 , R 3 , R 4 are groups forming an adequate enantiomer of the chelator; and X 1 -X 5 , Y 1 -Y 5 , Z 1 -Z 5 each individually forming pendant chelating groups.

  本发明提供了一种合成和结合方法，用于合成公式（VII）的五端基手性纯螯合剂，其中R1、R2、R3、R4是形成足够手性的螯合剂的基团；X1-X5、Y1-Y5、Z1-Z5各自形成悬垂螯合基团。
• Biltz; Giese, Chemische Berichte, 1904, vol. 37, p. 4013
  作者：Biltz、Giese

  DOI：——

  日期：——
• Zincke; Schaum, Chemische Berichte, 1894, vol. 27, p. 548
  作者：Zincke、Schaum

  DOI：——

  日期：——
• Pentachlorophenol: Uptake/elimination kinetics and metabolism in an aquatic plant,<i>Eichhornia Crassipes</i>
  作者：Sashwati Roy、Osmo Hänninen

  DOI：10.1002/etc.5620130511

  日期：1994.5

  AbstractEichhornia crassipes [(Mart) Solms], an aquatic plant widely used for the treatment of wastewaters, was used to study uptake/elimination kinetics and metabolism of pentachlorophenol (PCP). PCP is a well‐known industrial by‐product and a major pollutant of the aquatic environment. The initial phase of PCP uptake by the plant was rapid and reached a nearly steady state between 24 and 48 h of exposure to PCP. The major by‐products of PCP metabolism in Eichhornia crassipes were identified as ortho‐ and para‐ substituted chlorohydroxyphenols (chlorocatechols and ‐hydroquinones), ‐anisoles, and ‐veratroles. Partially dechlorinated products of PCP were also detected. A major portion of the absorbed PCP and metabolites was found in bound/conjugated form. The responses of the enzyme systems involved in the xenobiotic metabolism and antioxidative system were also studied following PCP exposure. A significant increase was observed in the activity of glutathione S‐transferase (GST), a major conjugating enzyme, and in the activities of superoxide dismutase and ascorbate peroxidase (Halliwell‐Asada pathway enzymes) of PCP exposed plants. Such responses of plant enzymes may be implemented as useful markers of aquatic pollution. The result related to the uptake and metabolism of PCP obtained from the present study suggests a crucial role of aquatic plants in determining the fate of environmental chemicals.
• KULBICH, T. S.;KOZLOVA, V. S., ZH. ANAL. XIMII, 45,(1990) N, S. 367-371
  作者：KULBICH, T. S.、KOZLOVA, V. S.

  DOI：——

  日期：——

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