2,4-二[(4-羟基苯基)甲基]苯酚 | 34826-64-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 中文名称: 2,4-二[(4-羟基苯基)甲基]苯酚
• 英文名称: 2,4-bis(4-hydroxybenzyl)phenol
• 英文别名: 2,4-Bis-(4-hydroxy-benzyl)-phenol；1-Hydroxy-2,4-bis-(4-hydroxybenzyl)benzene；2,4-bis[(4-hydroxyphenyl)methyl]phenol
• CAS: 34826-64-7
• 化学式: C₂₀H₁₈O₃
• 分子量: 306.361
• InChiKey: YQOVRUAPWCGSLC-UHFFFAOYSA-N

物化性质

• 熔点：
  142-145 °C(Solv: acetic acid, 35% (64-19-7); water (7732-18-5))
• 沸点：
  540.8±45.0 °C(Predicted)
• 密度：
  1.258±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  3

安全信息

• 海关编码：
  2907299090

反应信息

• 作为产物：
  描述：

  2,6-dibromo-4-bromomethyl-phenol 在 sodium hydroxide 、 aluminum nickel 、 硫酸 作用下， 生成 2,4-二[(4-羟基苯基)甲基]苯酚
  参考文献：
  名称：

  Finn et al., Journal of Applied Chemistry, 1954, vol. 4, p. 497,502

  摘要：

  DOI：

文献信息

• Accessing <i>para</i>-Alkylphenols via Iridium-Catalyzed Site-Specific Deoxygenation of Alcohols
  作者：Jing Wang、Tingting Wang、Hongguang Du、Ning Chen、Jiaxi Xu、Zhanhui Yang

  DOI：10.1021/acs.joc.3c01294

  日期：2023.9.1

  An iridium-catalyzed and phenol-directed deoxygenation of benzylic alcohols comes as an alternative access to 4-alkylphenols, featuring low catalyst loading (S/C up to 20,000, TOF up to 12,400 h–1), high functionality compatibility, and excellent site-selectivity. The applications in late-stage modification of steroids and gram-scale total synthesis of a Gastrodia elata extract are highlighted. Mechanistically

  铱催化和苯酚引导的苄醇脱氧是制备 4-烷基苯酚的替代方案，具有催化剂负载量低（S / C高达 20,000，TOF 高达 12,400 h –1）、高功能兼容性和优异的现场性等特点-选择性。重点介绍了天麻提取物在类固醇后期修饰和克级全合成中的应用。从机理上讲，醌甲基化物的中间作用控制了位点选择性，氢化铱的形成作为限速步骤。
• Purified Chemicals and Resins from Phenol and Formaldehyde
  作者：H. L. Bender、A. G. Farnham、J. W. Guyer、F. N. Apel、T. B. Gibb

  DOI：10.1021/ie50511a037

  日期：1952.7
• COATING FOR CONTROLLED RELEASE
  申请人：Dow Global Technologies LLC

  公开号：US20180179438A1

  公开（公告）日：2018-06-28

  Embodiments relate to a proppant particle or a solid article that includes a proppant particle/solid article and one or more coatings on an outer surface of the proppant particle/solid article including one or more well treatment agents and one or more controlled release polymer resins. Each well treatment agent is at least one selected from the group of a scale inhibitor, a wax inhibitor, a pour point depressant, asphaltene inhibitor, an asphaltene dispersant, a corrosion inhibitor, a biocide, a viscosity modifier, and a de emulsifier. Each controlled release polymer resin is at least one selected from the group of a polyurethane based resin, an epoxy resin, a phenolic resin, and a furan resin.
• COATING FOR CAPTURING SULFIDES
  申请人：Dow Global Technologies LLC

  公开号：US20180201825A1

  公开（公告）日：2018-07-19

  A coated proppant includes a solid core proppant particle, and a sulfide recovery coating that includes a sulfide capturing agent embedded within a polymer resin matrix. The sulfide capturing agent is a metal oxide.
• MODIFIED ARYLHYDROXY COMPOUNDS FOR THE PRODUCTION OF POLYURETHANE OR POLYISOCYANURATE
  申请人：Hexion GmbH

  公开号：US20220135731A1

  公开（公告）日：2022-05-05

  Esterified arylhydroxy compounds for the production of polyurethane or polyisocyanurate. In order to provide aromatic polyols for the production of polyurethanes or polyisocyanurates which are process-technically suitable in terms of their viscosity and at the same time give the end product good physical properties and a good reaction to fire, esterified arylhydroxy compounds are proposed as polyols.