2,5-二甲基-4-己烯-1-醇 | 42918-52-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2,5-二甲基-4-己烯-1-醇
• 英文名称: 2,5-dimethyl-4-hexen-1-ol
• 英文别名: dimethyl-2,5 hexen-4 ol-1；2,5-dimethyl-hex-4-en-1-ol；2,5-Dimethylhex-4-en-1-ol
• CAS: 42918-52-5
• 化学式: C₈H₁₆O
• 分子量: 128.214
• InChiKey: SDINZYGQOJFYLE-UHFFFAOYSA-N

物化性质

• 沸点：
  314-316 °C(Press: 4.00 Torr)
• 密度：
  0.844±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2,5-二甲基-4-己烯-1-醇 以72%的产率得到
  参考文献：
  名称：

  FUJITA, TSUTOMU;WATANABE, SHOJI;SUGA, KYOICHI;MIURA, TOSHIRO;SUGAHARA, KO+, J. CHEM. TECHNOL. AND BIOTECHNOL., 1982, 32, N 3, 476-484

  摘要：

  DOI：
• 作为产物：
  描述：

  magnesium,2-methylbut-2-ene,chloride 、 2-bromo-propan-1-ol; chloromagnesium(1+) salt 在 copper(I) bromide 作用下， 以 四氢呋喃 为溶剂， 生成 2,5-二甲基-4-己烯-1-醇
  参考文献：
  名称：

  Substitution directe de l'halogene d'halohydrines 1-2 par des organomagnesiens et lithiens en presence de sel cuivreux.

  摘要：

  DOI：

  10.1016/s0040-4039(01)95037-3

文献信息

• Stereoselective Synthesis of Pyrano[3,2-<i>c</i>]benzopyrans via Intramolecular Cycloaddition of <i>o</i>-Quinonemethides Generated from Salicylaldehydes and Unsaturated Alcohols under Very Mild Conditions
  作者：Hidekazu Miyazaki、Kiyoshi Honda、Masatoshi Asami、Seiichi Inoue

  DOI：10.1021/jo991132h

  日期：1999.12.1

  Intramolecular [4 + 2] cycloaddition reaction of 6-(4-alkenyloxymethylene)-2,4-cyclohexadien-1-ones generated from the reaction between substituted salicylaldehydes and unsaturated alcohols under mild conditions was investigated. In general, the reaction furnished tricyclic compounds containing the pyranobenzopyran skeleton with trans-fused B/C ring in very good yields (Tables 1 and 2). Furthermore, geometry of the olefinic bond of the starting material is retained during the reaction.
• NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT
  申请人：TEIJIN LIMITED

  公开号：EP1201235B1

  公开（公告）日：2005-10-12
• Bourgain-Commercon, Monique; Normant, Jean F., Bulletin de la Societe Chimique de France, 1980, vol. 2, # 5-6, p. 289 - 294
  作者：Bourgain-Commercon, Monique、Normant, Jean F.

  DOI：——

  日期：——
• Nickel-catalyzed regioselective allylation of allylic alcohols
  作者：Akira Yanagisawa、Nobuyoshi Nomura、Shigeki Habaue、Hisashi Yamamoto

  DOI：10.1016/s0040-4039(01)93908-5

  日期：1989.1
• A new strategy of tandem transetherification–intramolecular hetero Diels–Alder reaction with (E,Z)-mixture of ethyl 2-nitro-3-ethoxyacrylate and δ,ε-unsaturated alcohols leading to functionalized trans-fused bicyclic nitronates
  作者：Eiji Wada、Masahiko Yoshinaga

  DOI：10.1016/j.tetlet.2004.01.026

  日期：2004.3

  Tandem reaction of (E,Z)-ethyl 2-nitro-3-ethoxyacrylate (E:Z=25:75) with delta,epsilon-unsaturated alcohols leading to functionalized trans-fused bicyclic nitronates as single stereoisomers in high yields has been developed under thermal condition and in the presence of a catalytic amount of a Lewis acid catalyst such as Yb(OTf)(3). This process involves the configuration control of transetherified intermediates under a rapid, reversible transetherification reaction pathway for affording stereoselective trans-fused cyclic nitronates as single stereoisomers in intramolecular hetero Diels-Alder reaction. (C) 2001 Elsevier Ltd. All rights reserved.