2,5-哌嗪二羧酸 | 89601-10-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 2,5-哌嗪二羧酸
• 中文别名: 2,5二羧基L哌嗪
• 英文名称: 2,5-piperazinedicarboxylic acid
• 英文别名: Piperazin-2,5-dicarbonsaeure；2,5-Dicarboxypiperazine；piperazine-2,5-dicarboxylic acid；piperazine-1,4-diium-2,5-dicarboxylate
• CAS: 89601-10-5
• 化学式: C₆H₁₀N₂O₄
• mdl: MFCD01076328
• 分子量: 174.156
• InChiKey: FBYDNPVPBDAFFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -6.2
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.666
• 拓扑面积：
  98.7
• 氢给体数：
  4
• 氢受体数：
  6

安全信息

• 海关编码：
  2933599090

反应信息

• 作为产物：
  描述：

  吡嗪-2,5-二羧酸二甲酯 在 氢氧化钾 作用下， 生成 2,5-哌嗪二羧酸
  参考文献：
  名称：

  Effects of Body Weight Uniformity and Pre-Peak Feeding Programs on Broiler Breeder Hen Performance

  摘要：

  This study examined the effects of body weight (BW) uniformity on broiler breeder hen performance as well as the effects of post-lighting feeding programs on the uniformity and performance of nonuniform groups. Eight hundred Cobb-500 strain breeder females were housed in floor pens at 20 weeks of age. The HT treatment, which consisted of pullets that each weighed between 4.1 and 4.5 lb at housing, had high (H) uniformity and received typical (T) feed Increases. Three other treatments contained 25 light (3.4 to 3.8 lb) and 25 heavy (4.8 to 5.2 lb) birds in each pen. These treatments had low (L) uniformity and were subject to either T (LT) or fast (F) (LF) increases in pre-peak feed allotments or skip-a-day (S) feeding (LS) until 25 weeks of age. Results indicated that H initial uniformity was associated with increased egg production, and F feed allotment increases stimulated early egg production. The onset of lay was delayed in birds on the LS treatment, causing a decline in cumulative egg production and an increase in mean egg weight; but weekly egg production levels had recovered by 30 weeks. Modifications to pre-peak feeding programs may be an effective method to improve uniformity of nonuniform Becks.

  DOI：

  10.1093/japr/10.1.24
• 作为试剂：
  描述：

  、 、 2,5-吡嗪二羧酸 、 2,5-二甲基吡嗪 、 、 盐酸 、 、 trans-Piperazine-2,5-dicarboxylate 、 氨 、 the 1:1 H-bonded complex of pyridine and water 在 钯 2,5-哌嗪二羧酸 、 (2R,5S)-2,5-哌嗪二甲酸 、 甲醇盐酸 作用下， 以to produce the compound cis- or trans- piperazine 2,5-dicarboxamide的产率得到trans-piperazine-2,5-dicarboxamide
  参考文献：
  名称：

  Stereoisomeric tricyclic bis(dioxopiperazines) and pharmaceutical

  摘要：

  提供公式为##STR1##的立体异构三环双二酮哌嗪化合物，其中R为H或##STR2##的合成方法。这些化合物作为抗肿瘤或抗转移药物具有有效性。

  公开号：

  US04871736A1

文献信息

• COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS
  申请人：Chodorowski-Kimmes Sandrine

  公开号：US20100239509A1

  公开（公告）日：2010-09-23

  The present patent application relates to a cosmetic or dermatological composition comprising, in a cosmetically or dermatologically acceptable medium, a polymer comprising: (a) a polymer backbone that may be obtained by reaction: of a polyol comprising 3 to 6 hydroxyl groups; of a monocarboxylic acid containing 6 to 32 carbon atoms; of a polycarboxylic acid comprising at least two carboxylic groups COOH, and/or of a cyclic anhydride such as a polycarboxylic acid and/or of a lactone comprising at least one carboxylic group COOH; and (b) at least one junction group linked to the said polymer backbone and capable of establishing H bonds with one or more partner junction groups, each pairing of a junction group involving at least three H (hydrogen) bonds. The patent application also concerns a cosmetic treatment process using the said composition.

  本专利申请涉及一种化妆品或皮肤科学组合物，包括在化妆品或皮肤科学上可接受的介质中，包含以下聚合物的组合物：(a) 由以下反应得到的聚合物骨架：含有3至6个羟基的多元醇；含有6至32个碳原子的一元羧酸；至少含有两个羧基COOH的多元羧酸，和/或类似多元羧酸的环酐和/或至少含有一个羧基COOH的内酯；以及(b) 至少一个连接到所述聚合物骨架的连接基团，并能够与一个或多个配对连接基团建立H键，每个连接基团的配对涉及至少三个H（氢）键。该专利申请还涉及使用所述组合物的化妆品处理过程。
• COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION
  申请人：GIUSTINIANI Pascal

  公开号：US20090028807A1

  公开（公告）日：2009-01-29

  The present application relates to a cosmetic or pharmaceutical, in particular lipstick, composition comprising a polycondensate The application also relates to a method of cosmetic treatment using the composition, the polycondensate thus defined and a method of preparing the polycondensate.

  本申请涉及一种化妆品或药用品，特别是口红，包括聚缩酸酯的组合物。该申请还涉及一种使用该组合物进行化妆处理的方法，所述聚缩酸酯的定义以及一种制备聚缩酸酯的方法。
• COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT
  申请人：Malle Gerard

  公开号：US20100272660A1

  公开（公告）日：2010-10-28

  The present application relates to a cosmetic or pharmaceutical composition comprising a polycondensate capable of being obtained by the reaction of the following monomers alone: of 10 to 30% by weight, relative to the total weight of the polycondensate, of one or more polyols comprising 3 to 6 hydroxyl groups; of 30 to 80% by weight, relative to the total weight of the polycondensate, of one or more linear, branched and/or cyclic, saturated or unsaturated, non-aromatic monocarboxylic acids comprising 6 to 32 carbon atoms; of 1 to 40% by weight, relative to the total weight of the polycondensate, of one or more polycarboxylic acids and/or cyclic anhydrides of such a polycarboxylic acid and/or lactones comprising at least one COOH group; and optionally of 0.1 to 15% by weight, relative to the total weight of the polycondensate, of one or more silicones having a hydroxyl and/or carboxyl functional group. The application also relates to a method of cosmetic treatment using the said composition, and the polycondensate thus defined.

  本申请涉及一种化妆品或药用组合物，包括由以下单体反应而得的聚缩酸酯：相对于聚缩酸酯的总重量，占10至30%的一种或多种含有3至6个羟基的多元醇；占30至80%的一种或多种线性、支链和/或环状、饱和或不饱和、非芳香族的单羧酸，含有6至32个碳原子；占聚缩酸酯总重量的1至40%的一种或多种多羧酸和/或多羧酸的环状酐和/或含有至少一个COOH基团的内酯；以及可选地占聚缩酸酯总重量的0.1至15%的一种或多种硅氧烷，具有羟基和/或羧基官能团。该申请还涉及使用所述组合物进行化妆处理的方法，以及如此定义的聚缩酸酯。
• 置換ピペラジン化合物及び酸性ガス用の吸収剤、吸収液
  申请人：株式会社ＩＨＩ

  公开号：JP2018140981A

  公开（公告）日：2018-09-13

  【課題】 吸収液に調製して使用した際の組成変動を抑制可能な置換ピペリジン化合物、それを有効成分とする吸収剤、及び、それを用いて調製される、二酸化炭素等の酸性ガス処理用の吸収液を提供する。【解決手段】 置換ピペラジン化合物は、下記の一般式で表される。この置換ピペラジン化合物を有効成分とする吸収剤及び水を用いて、二酸化炭素等の酸性ガスを吸収処理する吸収液が調製される。【化１】【選択図】 図１

  这段文字描述了一种置换哌嗪化合物，可以抑制吸收液在制备和使用过程中的成分变化，以及一种以该化合物为有效成分的吸收剂和用于处理酸性气体如二氧化碳的吸收液。该置换哌嗪化合物由下列一般式表示，并且可以与水一起用于制备吸收液来吸收酸性气体。化学式和图表如下：【化１】【選択図】 図１
• Catalytic process for producing polyhydric alcohols
  申请人：UNION CARBIDE CORPORATION

  公开号：EP0006634A1

  公开（公告）日：1980-01-09

  This invention relates to the manufacture of polyhydric alcohol(s) by the reaction of synthesis gas in the presence of a rhodium carbonyl complex catalyst and a phosphine oxide compound.

  本发明涉及在羰基铑络合物催化剂和氧化膦化合物存在下，通过合成气反应制取多元醇。