2,6-二甲基-N-乙酰对硝基苯胺 | 114166-18-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,6-二甲基-N-乙酰对硝基苯胺
• 英文名称: 2,6-dimethyl-4-nitroacetanilide
• 英文别名: acetic acid-(2,6-dimethyl-4-nitro-anilide)；Essigsaeure-(2,6-dimethyl-4-nitro-anilid)；N-(2,6-dimethyl-4-nitro-phenyl)-acetamide；4-Nitro-2,6-dimethyl-N-acetyl-anilin；N-(2,6-dimethyl-4-nitrophenyl)acetamide
• CAS: 114166-18-6
• 化学式: C₁₀H₁₂N₂O₃
• 分子量: 208.217
• InChiKey: FVLFCHIARZIKGV-UHFFFAOYSA-N

物化性质

• 沸点：
  147 °C(Press: 0.003 Torr)
• 密度：
  1.247±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  74.9
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,6-二甲基-N-乙酰对硝基苯胺 在 锌 silica- 、 甲醇乙酸乙酯 、 碳酸氢钠 、 正庚烷 、 title compound 作用下， 以 四氢呋喃 、 溶剂黄146 为溶剂， 反应 0.67h， 以to furnish 1.20 g (28% yield) of the title compound as a pale red solid的产率得到N-(4-amino-2,6-dimethyl-phenyl)-acetamide
  参考文献：
  名称：

  Substituted aniline derivatives

  摘要：

  本发明涉及通式I的苯胺衍生物或其盐以及它们的用途。

  公开号：

  US20060155121A1
• 作为产物：
  描述：

  苯磺酸-(2,6-二甲基-4-硝基-苯胺) 在 硫酸 作用下， 生成 2,6-二甲基-N-乙酰对硝基苯胺
  参考文献：
  名称：

  Wepster, Recueil des Travaux Chimiques des Pays-Bas, 1954, vol. 73, p. 809,815

  摘要：

  DOI：

文献信息

• [EN] SUBSTITUTED ANILINE DERIVATIVES<br/>[FR] DERIVES D'ANILINE SUBSTITUES
  申请人：LUNDBECK & CO AS H

  公开号：WO2006029623A1

  公开（公告）日：2006-03-23

  The present invention relates to aniline derivatives of the general formula (I) or salts thereof and their use, related to their KCNQ potassium ion channel opening activity.

  本发明涉及一般式(I)的苯胺衍生物或其盐及其用途，与其KCNQ钾离子通道开放活性有关。
• SUBSTITUTED ANILINE DERIVATIVES
  申请人：Tornoe Christian Wenzel

  公开号：US20100063044A1

  公开（公告）日：2010-03-11

  The present invention relates to aniline derivatives of formula I: wherein R 1 , R 2 , R 3 , R 4 , Z and q are as defined herein; or salts thereof and their use.

  本发明涉及式I的苯胺衍生物：其中R1，R2，R3，R4，Z和q如本文所定义; 或其盐及其用途。
• OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE
  申请人：Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

  公开号：EP3326715A1

  公开（公告）日：2018-05-30

  The present invention provides oxalic amide ligands and uses thereof in copper-catalyzed coupling reaction of aryl halides. Specifically, the present invention provides a use of a compound represented by formula I, wherein definitions of each group are described in the specification. The compound represented by formula I can be used as a ligand in copper-catalyzed coupling reaction of aryl halides for the formation of C-N, C-O and C-S bonds.

  本发明提供了草酸酰胺配体及其在铜催化的芳基卤化物偶联反应中的用途。具体而言，本发明提供了一种由式 I 代表的化合物的用途，其中各基团的定义在说明书中有所描述。式 I 所代表的化合物可用作铜催化的芳基卤化物偶联反应中的配体，用于形成 C-N、C-O 和 C-S 键。
• Vanadium oxide compositions and systems and methods for creating them
  申请人：Dimien Inc.

  公开号：US10889505B2

  公开（公告）日：2021-01-12

  A system for creating targeted vanadium oxide (VO2) nanoparticle compositions comprising a stock reaction mixture that is a fluid combination of at least one vanadium source combined with at least one dopant source. Each dopant source contains at least one target dopant element. The ratio of the number of vanadium atoms in the vanadium source to the number of target dopant element atoms in the dopant source is less than or equal to 10:1. A solvent that is compatible with said stock reaction mixture is selected. A pressure regulator increases the pressure of the solvent and the stock reaction mixture to between 0 and 5,000 psi. A heating element increases the temperature of the solvent to between 50 and 500° C. A mixing unit receives and mixes a continuous flow of stock reaction mixture with solvent to heat the stock reaction mixture and initiate formation of the targeted vanadium oxide (VO2) nanoparticle composition.

  一种用于制造靶向氧化钒（VO2）纳米粒子组合物的系统，包括一种储备反应混合物，该混合物是至少一种钒源与至少一种掺杂源的流体组合。每个掺杂源含有至少一种目标掺杂元素。钒源中的钒原子数与掺杂源中的目标掺杂元素原子数之比小于或等于 10:1。选择与所述反应混合物相容的溶剂。压力调节器将溶剂和反应混合物的压力提高到 0 至 5,000 psi。加热元件将溶剂的温度升高到 50 至 500 摄氏度。混合装置接收并混合连续流动的浆料反应混合物和溶剂，以加热浆料反应混合物并开始形成目标氧化钒 (VO2) 纳米粒子组合物。
• Vanadium Oxide Compositions and Systems and Methods For Creating Them
  申请人：Dimien LLC

  公开号：US20170369330A1

  公开（公告）日：2017-12-28

  A system for creating targeted vanadium oxide (VO 2 ) nanoparticle compositions comprising a stock reaction mixture that is a fluid combination of at least one vanadium source combined with at least one dopant source. Each dopant source contains at least one target dopant element. The ratio of the number of vanadium atoms in the vanadium source to the number of target dopant element atoms in the dopant source is less than or equal to 10:1. A solvent that is compatible with said stock reaction mixture is selected. A pressure regulator increases the pressure of the solvent and the stock reaction mixture to between 0 and 5,000 psi. A heating element increases the temperature of the solvent to between 50 and 500° C. A mixing unit receives and mixes a continuous flow of stock reaction mixture with solvent to heat the stock reaction mixture and initiate formation of the targeted vanadium oxide (VO 2 ) nanoparticle composition.