2,6-二苯基-1,7-二氢吡咯并[3,2-f]吲哚 | 112274-31-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 中文名称: 2,6-二苯基-1,7-二氢吡咯并[3,2-f]吲哚
• 英文名称: 2,6-diphenyl-1,7-dihydro-pyrrolo[3,2-f]indole
• 英文别名: 2,6-Diphenyl-1,7-dihydro-pyrrolo[3,2-f]indol；2,6-Diphenyl-1,7-dihydropyrrolo[3,2-f]indole
• CAS: 112274-31-4
• 化学式: C₂₂H₁₆N₂
• 分子量: 308.382
• InChiKey: RZVWSPYDBZZOCS-UHFFFAOYSA-N

物化性质

• 沸点：
  615.9±50.0 °C(Predicted)
• 密度：
  1.259±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  31.6
• 氢给体数：
  2
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-溴辛烷 、 2,6-二苯基-1,7-二氢吡咯并[3,2-f]吲哚 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 、 mineral oil 为溶剂， 反应 4.0h， 以31%的产率得到1,7-dioctyl-2,6-diphenyl-1,7-dihydropyrrolo[3,2-f]indole
  参考文献：
  名称：

  通过双向金催化高效合成二吡咯并苯和二吡咯并吡嗪：合成和光物理联合研究

  摘要：

  新型 N-杂环荧光团是有机电子器件的热门化合物。在这里，我们报告了使用双向金催化环化策略以高产率获得间/对-二吡咯并苯和对-二吡咯并吡嗪的简单合成方法。通过制备具有不同取代基、各种官能团和多种取代模式的二吡咯芳烃，展示了我们反应方案的多功能性。此外，我们表明二吡咯并芳烃可以通过 N-烷基化进行后改性以提高溶解度或溴化以产生用于进一步衍生的前体交叉耦合。对几乎前所未有的二吡咯并芳烃的光物理性质的研究发现了强蓝色发射体，例如二苯基间二吡咯并苯，其量子产率为 98%。此外，我们发现溶剂极性的变化或与路易斯酸（如硼烷）的相互作用可用于微调荧光团的光物理性质。

  DOI：

  10.1021/jacs.2c02394
• 作为产物：
  描述：

  1,5-二氯-2,4-二硝基苯 在 乙醇 、 硫酸 、 水 、 镍 、 乙酸乙酯 、 苯 作用下， 生成 2,6-二苯基-1,7-二氢吡咯并[3,2-f]吲哚
  参考文献：
  名称：

  E MERGENCY M EDICAL P LANNING FOR THE 2000 R EPUBLICAN N ATIONAL C ONVENTION

  摘要：

  Planning for emergency medical services (EMS) coverage for the 2000 Republican National Convention in Philadelphia was a complex process that involved the cooperation of municipal, state, and federal agencies as well as local hospitals. The medical needs of the delegates, members of the media, and support personnel at the convention venue had to be met. Contingency plans for the possibility of large, organized political protests and associated injuries had to be developed. Steps had to be taken to ensure the safety of emergency personnel who may have to respond to such incidents. Because of the heightened threat of terrorist attacks on civilian populations in recent years, specialized training and material to respond to such incidents were required. The important role that local hospitals may play in providing care to victims of a large, multicasualty incident, especially one involving weapons of mass destruction, was recognized. Therefore, steps were taken to increase the awareness of hospital staff to patient decontamination and isolation techniques as well as specific therapies for the chemical, biological, and radioactive agents that terrorists might use. Finally, despite the focus placed on the convention, the day-to-day emergency medical needs of the citizens of Philadelphia had to be met. Through careful planning, flexibility, and cooperation, it was possible to successfully address all of these issues.

  DOI：

  10.1080/10903120190939490

文献信息

• Giuliano; Leonardi, Ricerca Scientifica, 1957, vol. 27, p. 1843,1846
  作者：Giuliano、Leonardi

  DOI：——

  日期：——
• E MERGENCY M EDICAL P LANNING FOR THE 2000 R EPUBLICAN N ATIONAL C ONVENTION
  作者：C. Crawford Mechem、Steven Hare、Robert Hvisdas、David M. Berg、Ralph Halper、Leonard A. Cola

  DOI：10.1080/10903120190939490

  日期：2001.1

  Planning for emergency medical services (EMS) coverage for the 2000 Republican National Convention in Philadelphia was a complex process that involved the cooperation of municipal, state, and federal agencies as well as local hospitals. The medical needs of the delegates, members of the media, and support personnel at the convention venue had to be met. Contingency plans for the possibility of large, organized political protests and associated injuries had to be developed. Steps had to be taken to ensure the safety of emergency personnel who may have to respond to such incidents. Because of the heightened threat of terrorist attacks on civilian populations in recent years, specialized training and material to respond to such incidents were required. The important role that local hospitals may play in providing care to victims of a large, multicasualty incident, especially one involving weapons of mass destruction, was recognized. Therefore, steps were taken to increase the awareness of hospital staff to patient decontamination and isolation techniques as well as specific therapies for the chemical, biological, and radioactive agents that terrorists might use. Finally, despite the focus placed on the convention, the day-to-day emergency medical needs of the citizens of Philadelphia had to be met. Through careful planning, flexibility, and cooperation, it was possible to successfully address all of these issues.
• Efficient Synthesis of Dipyrrolobenzenes and Dipyrrolopyrazines <i>via</i> Bidirectional Gold Catalysis: a Combined Synthetic and Photophysical Study
  作者：Robin Heckershoff、Tobias Schnitzer、Tim Diederich、Lukas Eberle、Petra Krämer、Frank Rominger、Matthias Rudolph、A. Stephen K. Hashmi

  DOI：10.1021/jacs.2c02394

  日期：2022.5.11

  New N-heterocyclic fluorophores are sought-after compounds for organic electronic devices. Here, we report on a straightforward synthesis to access meta/para-dipyrrolobenzenes and para-dipyrrolopyrazines in high yields using a bidirectional gold-catalyzed cyclization strategy. The versatility of our reaction protocol was showcased by preparing dipyrroloarenes with different substituents, various functional

  新型 N-杂环荧光团是有机电子器件的热门化合物。在这里，我们报告了使用双向金催化环化策略以高产率获得间/对-二吡咯并苯和对-二吡咯并吡嗪的简单合成方法。通过制备具有不同取代基、各种官能团和多种取代模式的二吡咯芳烃，展示了我们反应方案的多功能性。此外，我们表明二吡咯并芳烃可以通过 N-烷基化进行后改性以提高溶解度或溴化以产生用于进一步衍生的前体交叉耦合。对几乎前所未有的二吡咯并芳烃的光物理性质的研究发现了强蓝色发射体，例如二苯基间二吡咯并苯，其量子产率为 98%。此外，我们发现溶剂极性的变化或与路易斯酸（如硼烷）的相互作用可用于微调荧光团的光物理性质。