2-(2-乙基苯氧基)-N-甲基乙胺 | 57162-89-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 2-(2-乙基苯氧基)-N-甲基乙胺
• 英文名称: 2-(2-ethylphenoxy)-N-methylethanamine
• CAS: 57162-89-7
• 化学式: C₁₁H₁₇NO
• 分子量: 179.26
• InChiKey: VIKWYIGBGCPHGN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  21.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• COMPOUNDS THAT INTERACT WITH THE RAS SUPERFAMILY FOR THE TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE
  申请人：Shy Therapeutics LLC

  公开号：US20200061037A1

  公开（公告）日：2020-02-27

  Provided herein are methods and compositions for treating cancers, inflammatory diseases, rasopathies, and fibrotic disease involving aberrant Ras superfamily signaling through the binding of compounds to the GTP binding domain of Ras superfamily proteins including, in certain cases, K-Ras and mutants thereof, and a novel method for assaying such compositions.