N-[4-morpholin-4-yl-6-(2-phenylethoxy)-1,3,5-triazin-2-yl]-9H-carbazol-3-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: N-[4-morpholin-4-yl-6-(2-phenylethoxy)-1,3,5-triazin-2-yl]-9H-carbazol-3-amine
• 化学式: C₂₇H₂₆N₆O₂
• 分子量: 466.5
• InChiKey: LZKNLLCFBJVQER-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  35
• 可旋转键数：
  7
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  88.2
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• Method for treating B cell regulated autoimmune disorders
  申请人：Foley Kevin

  公开号：US20070032493A1

  公开（公告）日：2007-02-08

  The invention relates to a method for treating B-cell regulated autoimmune disorders using compounds that modulate the activity of c-Rel.
• PROCESS FOR PREPARING MESYLATE SALTS OF IL-12 INHIBITORY COMPOUNDS
  申请人：Kostik Elena

  公开号：US20090163708A1

  公开（公告）日：2009-06-25

  This invention relates to a method of preparing mesylate salts of compounds that inhibit IL-12, IL-23 and/or IL-27 production.
• TOPICAL FORMULATIONS FOR THE TREATMENT OF PSORIASIS
  申请人：Babu Suresh R.

  公开号：US20110098267A1

  公开（公告）日：2011-04-28

  The invention relates to a topical composition and a method for treating psoriasis. The topical composition comprises one or more compound that inhibits the production of IL-12 and IL-23.
• METHOD FOR TREATING B CELL REGULATED AUTOIMMUNE DISORDERS
  申请人：Foley Kevin

  公开号：US20120021434A1

  公开（公告）日：2012-01-26

  The invention relates to a method for treating B-cell regulated autoimmune disorders using compounds that modulate the activity of c-Rel.