N-(4-methylphenyl)-2-ethylaniline | 1412903-19-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-methylphenyl)-2-ethylaniline
• 英文别名: 2-ethyl-N-(p-tolyl)aniline；2-ethyl-N-(4-methylphenyl)aniline
• CAS: 1412903-19-5
• 化学式: C₁₅H₁₇N
• 分子量: 211.307
• InChiKey: RVAKNIXDIDGAFN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-乙基苯胺 、 对溴甲苯 在 、 sodium t-butanolate 作用下， 以 甲苯 为溶剂， 反应 22.0h， 生成 N-(4-methylphenyl)-2-ethylaniline
  参考文献：
  名称：

  Efficient catalytic aryl amination of bromoarenes using 3-iminophosphine palladium(II) chloride

  摘要：

  While pursuing the development of new hydroamination catalysts, a 3-iminophosphine palladium(II) chloride complex [(3IP)PdCl2] was synthesized that has subsequently proven to be an effective precatalyst for the aryl amination of bromoarenes. This (3IP)PdCl2 complex has been utilized in the catalytic aryl amination of both bromobenzene and bromopyridine derivatives, specifically yielding excellent activity in coupling reactions involving bromobenzene, 4-bromotoluene, and 2-bromopyridine. Using a standard set of catalytic conditions, many alkyl and aryl amines have been investigated as coupling partners in the aryl amination of bromoarenes. In general, secondary alkyl amines and ortho-substituted anilines proved to be the best substrates for this reaction, commonly giving quantitative conversion to products, while primary amines and other anilines gave only poor to moderate results. Catalytic screening data, product yields, and full characterization of isolated products are included. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2012.08.027

文献信息

• Base-assisted, copper-catalyzed N-arylation of (benz)imidazoles and amines with diarylborinic acids
  作者：Changwei Guan、Yuanyuan Feng、Gang Zou、Jie Tang

  DOI：10.1016/j.tet.2017.10.043

  日期：2017.12

  cost-effective aryl source has been efficiently effected via Cu(OAc)2-catalyzed Chan-Lam coupling in assistance of tetramethylethylenediamine (TMEDA) in methanol and pyridine (Py) in dichloromethane, respectively, in air at room temperature. The diarylborinic acids could be well accommodated by the Chan-Lam coupling oxidative conditions containing a proper combination of bases and solvents. The steric

  借助Cu（OAc）2催化的Chan-Lam偶联，借助四甲基乙二胺（TMEDA）在甲醇和吡啶（Py）中的催化作用，已有效地实现了（苯）咪唑和胺与二芳基硼酸作为具有成本效益的芳基源的N-芳基化作用。室温下分别置于二氯甲烷中。包含适当的碱和溶剂组合的Chan-Lam偶联氧化条件可以很好地容纳二芳基硼酸。与电子因素相比，使用高阶芳基硼试剂时，空间位阻似乎对铜催化的N-芳基化的影响更大，尤其是对于低反应性苯胺和脂肪族胺而言。
• <i>o</i>-Iodoxybenzoic Acid Mediated<i>N</i>-Arylation of Aromatic Amines by Using Arylhydrazines as the Arylating Counterpart
  作者：Ravindra R. Jadhav、Sameerana N. Huddar、Krishnacharya G. Akamanchi

  DOI：10.1002/ejoc.201300917

  日期：2013.10

  the combination of arylhydrazines with o-iodoxybenzoic acid (IBX) for the generation of aryl free radicals. On the basis of this finding, a method was developed for the N-arylation of aromatic amines under mild conditions (base-free, –5 °C) by using arylhydrazines as the arylating counterpart and arylamines. The scope of this method was demonstrated by using a number of arylhydrazines and arylamines,

  通过自由基捕获实验，我们首次建立了芳基肼与邻碘苯甲酸 (IBX) 的组合以产生芳基自由基。在此发现的基础上，通过使用芳基肼作为芳基化对应物和芳基胺，开发了一种在温和条件（无碱，–5°C）下芳胺 N-芳基化的方法。通过使用多种芳基肼和芳基胺证明了该方法的适用范围，它们以良好的产率得到了 N-芳基化胺。
• TERPHENYL COMPOUND, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND METHOD FOR PRODUCING TERPHENYL COMPOUND
  申请人：KYOCERA Document Solutions Inc.

  公开号：US20200231535A1

  公开（公告）日：2020-07-23

  A compound is represented by general formula (1). In general formula (1), R 1 and R 2 each represent, independently of one another, a hydrogen atom, a methyl group, or an ethyl group, and a sum of the number of carbon atoms of the chemical group represented by R 1 and the number of carbon atoms of the chemical group represented by R 2 is 2. R 3 and R 4 each represent, independently of one another, a hydrogen atom, a methyl group, or an ethyl group, and a sum of the number of carbon atoms of the chemical group represented by R 3 and the number of carbon atoms of the chemical group represented by R 1 is 2. A photosensitive layer of an electrophotographic photosensitive member contains at least a charge generating material, a hole transport material, and a binder resin. The hole transport material includes a compound represented by general formula (1)

  化合物用一般式（1）表示。在一般式（1）中，R1和R2各自独立地表示氢原子、甲基基团或乙基基团，以及由R1表示的化学基团的碳原子数和由R2表示的化学基团的碳原子数之和为2。R3和R4各自独立地表示氢原子、甲基基团或乙基基团，以及由R3表示的化学基团的碳原子数和由R1表示的化学基团的碳原子数之和为2。电子照相感光成员的光敏层至少包含一个电荷发生材料，一个空穴传输材料和一个粘合树脂。空穴传输材料包括一个由一般式（1）表示的化合物。
• Terphenyl compound, electrophotographic photosensitive member, and method for producing terphenyl compound
  申请人：KYOCERA Document Solutions Inc.

  公开号：US11067909B2

  公开（公告）日：2021-07-20

  A compound is represented by general formula (1). In general formula (1), R1 and R2 each represent, independently of one another, a hydrogen atom, a methyl group, or an ethyl group, and a sum of the number of carbon atoms of the chemical group represented by R1 and the number of carbon atoms of the chemical group represented by R2 is 2. R3 and R4 each represent, independently of one another, a hydrogen atom, a methyl group, or an ethyl group, and a sum of the number of carbon atoms of the chemical group represented by R3 and the number of carbon atoms of the chemical group represented by R1 is 2. A photosensitive layer of an electrophotographic photosensitive member contains at least a charge generating material, a hole transport material, and a binder resin. The hole transport material includes a compound represented by general formula (1)

  一种化合物由通式（1）表示。在通式（1）中，R1 和 R2 各自独立地代表氢原子、甲基或乙基，且 R1 所代表的化学基团的碳原子数与 R2 所代表的化学基团的碳原子数之和为 2。R3 和 R4 各自独立地代表氢原子、甲基或乙基，且 R3 所代表的化学基团的碳原子数与 R1 所代表的化学基团的碳原子数之和为 2。 电子照相感光构件的感光层至少包含电荷生成材料、孔传输材料和粘合剂树脂。空穴传输材料包括通式 (1) 所代表的化合物
• High performance lubricant containing high molecular weight aromatic amine antioxidant and low boron content dispersant
  申请人：Goyal Arjun Kumar

  公开号：US20070232504A1

  公开（公告）日：2007-10-04

  A method for improving the seal integrity, oxidation resistance, thermal breakdown deposit protection of lubricating oil by combining a base stock and/or base oil with a high molecular weight aromatic amine and a low boron content dispersant.