| 1014625-61-6

• CAS: 1014625-61-6
• 化学式: C₂₂H₂₆Cl₂NPPd
• 分子量: 512.755
• InChiKey: BIROXELBAQRIGL-WUCHBLMUSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  以 氘代氯仿 、 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  Reactivity of (3-Iminophosphine)palladium(II) Complexes: Evidence of Hemilability

  摘要：

  Several palladium(II) 3-iminophosphine complexes were synthesized in moderate to high yield. With relevance to many palladium-catalyzed coupling reactions, these complexes incorporate a wide variety of ligands, including amines, alkyls, allyls, and triflates. The presence of both eta'- and eta(2)-coordination modes demonstrates the hemilability of the 3-iminophosphine ligand class, as determined by X-ray crystallography and NMR spectroscopy.

  DOI：

  10.1021/om900066t
• 作为试剂：
  描述：

  3-溴吡啶 、 甲基丁胺 在 、 sodium t-butanolate 作用下， 以 甲苯 为溶剂， 反应 22.0h， 生成 N-butyl-N-methyl-(pyridin-3-yl)amine
  参考文献：
  名称：

  Efficient catalytic aryl amination of bromoarenes using 3-iminophosphine palladium(II) chloride

  摘要：

  While pursuing the development of new hydroamination catalysts, a 3-iminophosphine palladium(II) chloride complex [(3IP)PdCl2] was synthesized that has subsequently proven to be an effective precatalyst for the aryl amination of bromoarenes. This (3IP)PdCl2 complex has been utilized in the catalytic aryl amination of both bromobenzene and bromopyridine derivatives, specifically yielding excellent activity in coupling reactions involving bromobenzene, 4-bromotoluene, and 2-bromopyridine. Using a standard set of catalytic conditions, many alkyl and aryl amines have been investigated as coupling partners in the aryl amination of bromoarenes. In general, secondary alkyl amines and ortho-substituted anilines proved to be the best substrates for this reaction, commonly giving quantitative conversion to products, while primary amines and other anilines gave only poor to moderate results. Catalytic screening data, product yields, and full characterization of isolated products are included. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2012.08.027