2-nitrobenzenecarboximidamide; hydrochloride salt | 64633-88-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-nitrobenzenecarboximidamide; hydrochloride salt
• 英文别名: 2-Nitrobenzene-1-carboximidamide hydrochloride；2-nitrobenzenecarboximidamide;hydrochloride
• CAS: 64633-88-1
• 化学式: C₇H₇N₃O₂*ClH
• 分子量: 201.612
• InChiKey: AUXXZZHQJXFJTC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  95.7
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-nitrobenzenecarboximidamide; hydrochloride salt 在 palladium 10% on activated carbon 氢气 作用下， 以 甲醇 为溶剂， 反应 0.33h， 生成 2-aminobenzimidamide dihydrochloride
  参考文献：
  名称：

  WO2007/58583

  摘要：

  公开号：
• 作为产物：
  描述：

  2-硝基苯甲腈 在 lithium hexamethyldisilazane 、 盐酸 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 反应 2.17h， 生成 2-nitrobenzenecarboximidamide; hydrochloride salt
  参考文献：
  名称：

  WO2007/58583

  摘要：

  公开号：

文献信息

• TRIAZINE-BASED COMPOUND AND ULTRAVIOLET ABSORBER
  申请人：AMASAKI Ichiro

  公开号：US20120053343A1

  公开（公告）日：2012-03-01

  A compound represented by the following formula (1): wherein each of R 1b , R 1c , R 1d , R 1g , R 1h , R 1i , R 1k , R 1m , R 1n and R 1p independently represents a hydrogen atom or a monovalent substituent, the monovalent substituents may combine with each other to form a ring, provided that at least one of R 1c and R 1h represents a hydrogen atom or a substituent having a positive σp value of the Hammett's rule, each of R 1a , R 1e , R 1f and R 1j independently represents a hydrogen atom or a monovalent substituent excluding —NHY 1 and —OH, Y 1 represents —COR 1q or —SO 2 R 1r , and each of R 1q and R 1r independently represents a monovalent substituent.

  以下公式（1）所代表的化合物：其中R1b、R1c、R1d、R1g、R1h、R1i、R1k、R1m、R1n和R1p中的每一个独立地代表氢原子或一价取代基，这些一价取代基可以相互结合形成环，前提是R1c和R1h中至少有一个代表氢原子或具有Hammett规则的正σp值的取代基，R1a、R1e、R1f和R1j中的每一个独立地代表氢原子或一价取代基，但不包括—NHY1和—OH，Y1代表—COR1q或—SO2R1r，R1q和R1r中的每一个独立地代表一价取代基。
• Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests
  申请人：——

  公开号：US20040242645A1

  公开（公告）日：2004-12-02

  This invention pertains to compounds of Formula I, their N-oxides and suitable salts (Formula I) wherein A is O or S; G is a 5- or 6-membered heteroaromatic ring or a 5- or 6-membered nonaromatic heterocyclic ring optionally including one or two ring members selected from the group consisting of C(═O), SO or S(O) 2 , each ring optionally substituted with from one to four R 2 ; each J is independently a phenyl ring, a 5- or 6-membered heteroaromatic ring or an aromatic 8-, 9- or 10-membered fused carbobicyclic or heterobicyclic ring system, wherein each ring or ring system is optionally substituted with from one to four R 3 ; and R 1 , R 2 , R 3 , R 4 and n are as defined in the disclosure. Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of Formula I, an N-oxide thereof or a suitable salt of the compound (e.g., as a composition described herein). This invention also pertains to a composition for controlling an invertebrate pest comprising a biologically effective amount of a compound of Formula I, an N-oxide thereof or a suitable salt of the compound and at least one additional component selected from the group consisting of surfactants, solid diluents and liquid diluents. 1

  本发明涉及式I的化合物，其N-氧化物和适宜的盐（式I）其中A是O或S; G是5-或6-成员杂芳环或5-或6-成员非芳杂环，可选地包括一个或两个环成员，所选自C（═O），SO或S（O）2的群，每个环可选地取代1-4个R2; 每个J是独立的苯环，5-或6-成员杂芳环或芳香8-、9-或10-成员融合碳杂双环系统，其中每个环或环系统可选地取代1-4个R3; R1、R2、R3、R4和n如本公开说明中所定义。本发明还公开了一种控制无脊椎动物害虫的方法，包括将无脊椎动物害虫或其环境与式I的化合物，其N-氧化物或化合物的适宜盐的生物有效量接触（例如，作为本文所述的组合物）。本发明还涉及一种用于控制无脊椎动物害虫的组合物，其包括式I的化合物、其N-氧化物或化合物的适宜盐的生物有效量和至少一种来自表面活性剂、固体稀释剂和液体稀释剂的群体中选择的其他成分。
• Therapeutic agents
  申请人：Bristol-Myers Company

  公开号：US04082751A1

  公开（公告）日：1978-04-04

  A series of 2-(substituted)phenyl-5-(5-1H-tetrazolyl)pyrimidin-4(3H)-ones is provided for use as inhibitors of allergic reactions. The compounds show antiallergy activity by both oral and parenteral routes of administration.

  提供了一系列2-(取代)苯基-5-(5-1H-四唑基)嘧啶-4(3H)-酮，用于作为过敏反应的抑制剂。这些化合物通过口服和注射途径均表现出抗过敏活性。
• Novel 2-Amino-Heterocycles Useful in the Treatment of Abeta-Related Pathologies
  申请人：Albert Jeffrey

  公开号：US20080293709A1

  公开（公告）日：2008-11-27

  This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salts, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.

  本发明涉及具有下面结构式I的新化合物，以及它们的药学上可接受的盐、组合物和使用方法。这些新化合物提供了治疗或预防认知障碍、阿尔茨海默病、神经退行性疾病和痴呆症的方法。
• Herbicidal sulfonamides
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0083975A2

  公开（公告）日：1983-07-20

  Novel benzenesulfonamide derivatives of formula wherein Q is selected from various five and six membered heterocyclic groups which are optionally substituted ; R, is H, F, Cl, Br, CH3, CF3 or OCH3; R13 is H or CH3; W" is O or S; and A is a substituted heterocyclic moiety: and their agriculturally suitable salts, exhibit potent herbicidal activity. Some are also of interest as plant growth regulants. The novel compounds may be formulated for use in conventional manner. They may be made by a variety of methods, e.g. by reacting a sulfonamide of formula with a methyl carbamate of formula

  式中的新型苯磺酰胺衍生物 其中 Q 选自各种任选被取代的五元和六元杂环基团； R 是 H、F、Cl、Br、CH3、CF3 或 OCH3； R13 是 H 或 CH3； W "是O或S；以及 A 是取代的杂环分子： 以及它们在农业上适用的盐类具有很强的除草活性。有些还可作为植物生长调节剂。 新型化合物可按常规方法配制使用。它们可以通过多种方法制得，例如通过将式 与式